Results 141 to 150 of about 155,160 (352)

Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa   +2 more
wiley   +1 more source

Total Pancreatectomy with Islet Auto-transplantation in Chronic Pancreatitis is the Call of our Time.

open access: yesAlbanian Journal of Trauma and Emergency Surgery
Introduction: Total pancreatectomy with islet auto-transplantation is a realistic therapeutic choice and an advanced surgical operation for individuals with chronic pancreatitis.
Nerida Dhigoi   +5 more
doaj   +1 more source

Pseudocyst in the Pancreatic Tail Associated with Chronic Pancreatitis Successfully Treated by Transpapillary Cyst Drainage [PDF]

open access: gold, 2008
Itaru Naitoh   +12 more
openalex   +1 more source

Global Leadership Initiative on Malnutrition as a predictor of mortality and prolonged hospitalization in emergency department patients: A prospective cohort study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Early diagnosis of malnutrition is essential for rapid decision‐making regarding nutrition care to improve patient outcomes. We aimed to evaluate the prevalence of malnutrition using the Global Leadership Initiative on Malnutrition (GLIM) criteria and to assess the association of GLIM with 1‐year mortality and length of hospital ...
Renata Wolf   +4 more
wiley   +1 more source

Addressing the distressing: Pancreatic enzyme replacement therapy mitigates abdominal symptoms and weight loss during chemotherapy for advanced pancreatic cancer: A prospective study

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Pancreatic enzyme insufficiency (PEI) contributes to symptom burden and malnutrition in advanced pancreatic cancer (aPC). We aimed to evaluate the impact of pancreatic enzyme replacement therapy (PERT) on symptom burden and weight during chemotherapy.
Pamela N. Klassen   +6 more
wiley   +1 more source

Increased awareness enhances physician recognition of the role of smoking in chronic pancreatitis

open access: green, 2019
Thiruvengadam Muniraj   +22 more
openalex   +2 more sources

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