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Chronic pancreatitis: A path to pancreatic cancer
Cancer Letters, 2014Chronic pancreatitis predisposes to pancreatic cancer development and both diseases share a common etiology. A central role has been proposed for the digestive enzyme-secreting acinar cell that can undergo ductal metaplasia in the inflammatory environment of pancreatitis.
Pinho, Andreia V +2 more
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Surgical Clinics of North America, 1981
Chronic pancreatitis is marked by recurrent bouts of pain, complications of pancreatitis, and progressive exocrine and endocrine dysfunction. Objective complications are generally well managed, although they do not alter the natural or progressive course of the disease. Treatment of palpable pseudocysts is varied, and the multiple surgical alternatives
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Chronic pancreatitis is marked by recurrent bouts of pain, complications of pancreatitis, and progressive exocrine and endocrine dysfunction. Objective complications are generally well managed, although they do not alter the natural or progressive course of the disease. Treatment of palpable pseudocysts is varied, and the multiple surgical alternatives
openaire +2 more sources
Pancreatic enzymes for chronic pancreatitis
Cochrane Database of Systematic Reviews, 2009The efficacy of pancreatic enzymes in reducing pain and improving steatorrhoea is debatable and the evidence base for their utility needs to be determined.To evaluate the efficacy of pancreatic enzymes in patients with chronic pancreatitis. The specific objectives were to compare the following: 1) pancreatic enzyme versus placebo; 2) different ...
Nusrat, Shafiq +7 more
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Chronic Pancreatitis and Pancreatic Cancer
New England Journal of Medicine, 1993Pancreatic cancer is the 5th leading cause of death from cancer and the 11th most common cancer in the United States1; each year 24,000 people die of pancreatic cancer in this country. The incidence of pancreatic cancer increased dramatically several decades ago, but it has remained fairly stable over the past 15 years (9.1 per 100,000).
E B, Gold, J L, Cameron
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Hospital Medicine, 2000
Chronic pancreatitis causes destruction of the pancreatic gland which leads to diabetes and malabsorption. Its principal cause is alcohol abuse, and intractable pain is the main clinical feature. The incidence of pancreatic carcinoma is increased among patients with chronic pancreatitis.
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Chronic pancreatitis causes destruction of the pancreatic gland which leads to diabetes and malabsorption. Its principal cause is alcohol abuse, and intractable pain is the main clinical feature. The incidence of pancreatic carcinoma is increased among patients with chronic pancreatitis.
openaire +2 more sources