Results 61 to 70 of about 155,160 (352)

Dissipatively Fueled Unidirectionally Communicating DNA Circuits That Control Biocatalysis

Angewandte Chemie, EarlyView.
Unidirectionally communicating, out‐of‐equilibrium DNA circuits are used to control enzyme activity. Transient DNAzyme activation generates fuel for temporal trypsin activation. Cyclic fuel‐driven hybridization and exonuclease‐mediated reset enable precise control over lifetimes, which is analyzed using combined experimental and computational ...
Philippe Jung, Daniel Felder, Gurudas Chakraborty, Tim Seifert, Matthias Wessling, Lifei Zheng, Andreas Herrmann   +6 more
wiley   +2 more sources

Synergistic effects of PAR2 and TrkA exacerbate visceral hypersensitivity induced by chronic pancreatitis in rats

IBRO Neuroscience Reports
Background: Abdominal pain is the most severe symptom of chronic pancreatitis. However, till date, there are only a few studies on the mechanism of pain in chronic pancreatitis.
Zhiyun Liu, Jiao Zhu, Qianbo Chen, Kunming Tao, Kai Wei, Xiaodan Wu, Haibo Qiu, Zhijie Lu   +7 more
doaj   +1 more source

Do changes in health reveal the possibility of undiagnosed pancreatic cancer? Development of a risk-prediction model based on healthcare claims data. [PDF]

, 2019
Background and objectiveEarly detection methods for pancreatic cancer are lacking. We aimed to develop a prediction model for pancreatic cancer based on changes in health captured by healthcare claims data.MethodsWe conducted a case-control study on 29 ...
Baecker, Aileen, Hendifar, Andrew E, Jeon, Christie Y, Kim, Sungjin, Nuckols, Teryl K, Pandol, Stephen J, Pisegna, Joseph R, Risch, Harvey A, Wu, Bechien U   +8 more
core   +2 more sources

Bifidobacterium Breve Yang08 Alleviates Atopic Dermatitis By Enriching Akkermansia Muciniphila and Inhibiting Neutrophil Extracellular Traps Formation In Mice

Advanced Science, EarlyView.
A novel Bifidobacterium breve strain, Yang08, is isolated to counter its depletion in atopic dermatitis. In mice, live Yang08 requires an intact gut microbiota to exert protection, specifically enriching Akkermansia muciniphila and potently inhibiting pathogenic neutrophil activation and NETosis in the skin.
Yanqiang Shi, Shuang He, Chengyi Li, Hung Chan, Zhenfeng Liu, Bin Yang, Qing Li   +6 more
wiley   +1 more source

Quality of life in patients with comorbidity of chronic pancreatitis and chronic obstructive pulmonary disease in presence of smoking

Infusion & Chemotherapy, 2019
Background. A combination of chronic pancreatitis and chronic obstructive pulmonary disease is quite common in clinical practice. This has a negative effect on the clinical course of both diseases.
L. S. Babinets, О. S. Kvasnitska
doaj   +1 more source

The use of complementary and alternative medicine is frequent in patients with pancreatic disorder [PDF]

, 2016
BACKGROUND: Herbal remedies and other complementary and alternative medicine (CAM) are used by 30% of the patients with liver and inflammatory bowel diseases.
Archibugi, L, Capurso, G., DELLE FAVE, Gianfranco, Stigliano, S, Zerboni, G   +4 more
core   +1 more source

Possible Therapeutic Effect of Ghrelin and Exosomes Derived from Mesenchymal Stem Cells on Induced Chronic Pancreatitis of Adult Albino Rats (Histological and Immunohistochemical Study) [PDF]

, 2022
Walaa Attaia, Mohammed Yousef, Nahla El-Eraky El-Azab, Nessrein Salem, S Bansod, A Khurana, C Godugu, T Napolitano, S Silvano, A Vieira, S Balaji, A Garrido-Utrilla, M Friano, M Tkach, C Thry, M Colombo, G Raposo, C Thry, S El Andaloussi, I Mger, X Breakefield, M Wood, M Zhang, X Zang, M Wang, Z Li, M Qiao, H Hua, E Eltantaway, G Khalaf, G Hamam, C Tmer, H Bilgin, B Obay, H Diken, E Tademir, A ermet, N El-Azab, A El-Mahalawaya, O Mostafa, D Sabry, R Mohamady, O Mohamed, L Seys, F Verhamme, A Schinwald, H Hammad, D Cunoosamy, D Mason, J Cordell, P Gaulard, A Tse, M Brown, C Kwon, J Cho, S Choi, K Ko, T H; Tirkes, M Gromski, E Moustafa, F Moawed, G Abdel-Hamid, S Sharma, S Rana, S Rana, D Bhasin, R Nada, S Malhotra, S Nadella, V Ciofoaia, H Cao, B Kallakury, R Tucker, J Smith, G Soliman, W Ibrahim, H Abdallah, G Biczo, E Vegh, N Shalbueva, O Mareninova, J Elperin, E Lotshaw, M Manohar, A Verma, S Venkateshaiah, A Mishra, A Lugea, L Nan, S French, J Bezerra, A Gukovskaya, S Pandol, P Hegyi, T Takcs, L Tiszlavicz, L Czak, J Lonovics, Z Warzecha, P Ceranowicz   +99 more
openalex   +1 more source

TGM2 Aggravates Acute Pancreatitis by Impairing Macrophage Efferocytosis Through Inhibition of the STAT6–GAS6 Axis

Advanced Science, EarlyView.
This study shows TGM2 is upregulated in AP, impairing macrophage efferocytosis by inhibiting the STAT6–GAS6 axis. The lactoferrin‐modified, ROS‐responsive LF‐LNP@si‐TGM2 targets pancreatic macrophages, silences TGM2, restores the axis, and alleviates AP.
Xuxu Liu, Zhiwei Du, Liyi Wang, Zhihong Xie, Ziang Meng, Yi Zheng, Heming Wang, Yuanhang He, Dongbo Xue   +8 more
wiley   +1 more source

Asparaginase-Induced Acute Necrotizing Pancreatitis Resulting in Chronic Pancreatitis and Pseudocyst in an Adult with Acute Lymphocytic Leukemia

The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2023
L-Asparaginase is one of the main chemotherapy regiments for acute lymphocytic leukemia (ALL) management. Acute pancreatitis is one of the serious side effects of l-asparaginase administration and may lead to interruption of chemotherapy cycle. Long term
Randy Adiwinata, Bradley Jimmy Waleleng, Harlinda Haroen, Linda Rotty, Fandy Gosal, Luciana Rotty, Cecillia Hendratta, Pearla Lasut, Jeanne Winarta, Andrew Waleleng, Michael Tendean   +10 more
doaj   +1 more source

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. [PDF]

, 2018
Background & aimsHeavy alcohol drinking is associated with pancreatitis, whereas moderate intake lowers the risk. Mice fed ethanol long term show no pancreas damage unless adaptive/protective responses mediating proteostasis are disrupted. Pancreatic
Abrol, Ravinder, Capri, Joseph, Cohn, Whitaker, Faull, Kym F, Freeman, Michael R, Lugea, Aurelia, Pandol, Stephen J, Piplani, Honit, Sakkiah, Sugunadevi, Su, Hsin-Yuan, Waldron, Richard T, Whitelegge, Julian P, Yang, Wei, Zhou, Bo   +13 more
core   +3 more sources