Results 121 to 130 of about 70,647 (287)

Slow Transit Constipation: Pathophysiological Perspectives and Management Updates

open access: yesJournal of Digestive Diseases, EarlyView.
Slow transit constipation (STC) is a complex neuromuscular disorder driven by interstitial cells of Cajal (ICCs) loss and enteric neuropathy. Diagnosis relies on objective transit testing while excluding pelvic floor dysfunction. Management follows a stepwise, phenotype‐driven approach, progressing from conventional laxatives to emerging targeted ...
Athanasios Syllaios   +8 more
wiley   +1 more source

Occult presentation of spinal epidural abscess

open access: yes
PM&R, EarlyView.
Rotem Hass   +3 more
wiley   +1 more source

Tissue‐retained needles in people who inject drugs: A systematic review of case reports and series on clinical presentations, complications and management

open access: yesAddiction, EarlyView.
Abstract Background and aims Tissue‐retained needles from intravenous drug use can cause rare but severe complications, ranging from local to systemic infections to needle embolization. Due to the limited evidence and the lack of epidemiological studies on the issue, we systematically reviewed the literature focusing on case reports and case series on ...
Heidi Laukkala   +7 more
wiley   +1 more source

Conservative management of low back pain [PDF]

open access: yes, 2001
Back pain is prevalent worldwide, but back pain disability has reached epidemic proportions in many industrialised societies. Few patients have serious medical pathology or direct neurological involvement requiring surgery.
De Souza, LH, Frank, AO
core  

Individualized T3‐4N+ Rectal Cancer Treatment Strategies: Exploring the Efficacy of Preoperative Synchronized Lateral Lymph Node Simultaneous Integrated Boost Radiation Therapy

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
Anatomical Diagram: It shows a cross‐section of the pelvic area highlighting the rectum and lateral lymph nodes, which are the focal points of the treatment strategy discussed in the paper. Flowchart: It outlines the treatment process from preoperative synchronized radiation therapy to the subsequent surgical procedures, illustrating the sequence of ...
Xinjue Shi   +7 more
wiley   +1 more source

Pelvic pain and lower urinary tract symptoms; long‐term comparison between women with and without mid‐urethral sling insertion

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Women aged 50 or above, who have undergone mid‐urethral sling surgery 10–14 years earlier for stress urinary incontinence, report more pelvic pain than age‐matched women. Other lower urinary tract symptoms also seem to be more prevalent in women 50 years or above with previous surgery.
Anna Lundmark Drca   +4 more
wiley   +1 more source

Impact of episiotomy on anal incontinence following second‐ to fourth‐degree perineal tears—A cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
In over 12 000 Swedish primiparous women, anal incontinence was more common after severe perineal tears. Episiotomy did not raise the overall risk except for a slight increase in gas incontinence after second‐degree tears. Encouragingly, symptoms improved across all types of tears during the first‐year postpartum.
Mette L. Josefsson   +5 more
wiley   +1 more source

Abuse history as a modifier of symptom phenotype in endometriosis: Insights from a multidimensional retrospective cohort

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Patients with endometriosis and abuse history reported greater pain, gastrointestinal symptoms, and central sensitization. Recognizing this compounded profile supports early psychosocial screening to complement biomedical management. Abstract Introduction Endometriosis is a heterogeneous pain condition with variable symptom expression.
Shay M. Freger   +5 more
wiley   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

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