Results 151 to 160 of about 70,647 (287)

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

Endoscopic Step‐up Approach for Walled‐off Necrosis After Acute Pancreatitis

open access: yesDEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT This review outlines current interventional strategies for treating symptomatic walled‐off necrosis (WON) after necrotizing pancreatitis. Mortality from acute pancreatitis has improved, but late mortality, particularly from infected necrosis, remains a challenge. WON requires invasive treatment in cases of infection or symptoms.
Shuntaro Mukai   +13 more
wiley   +1 more source

Mitochondrial DNA Depletion Syndrome 1 (MTDPS1)—A Novel Cause of Premature Ovarian Insufficiency

open access: yesClinical Genetics, Volume 109, Issue 4, Page 784-787, April 2026.
We describe a woman with MNGIE due to a novel homozygous TYMP nonsense variant and propose MNGIE as the cause of her premature ovarian insufficiency—a rarely reported association—highlighting the need to consider mitochondrial disease in unexplained POI, especially in atypical, consanguineous presentations. ABSTRACT Mitochondrial DNA depletion syndrome
Michael Matheou   +3 more
wiley   +1 more source

Multi‐Omics Data Reveal Estrogen‐Driven Dysregulation and Stromal‐Epithelial Signaling Alterations in Endometrial Polyps

open access: yesThe FASEB Journal, Volume 40, Issue 5, 15 March 2026.
Single‐cell transcriptomic profiling reveals that endometrial polyps arise from estrogen‐driven disruption of stromal‐epithelial signaling. Stromal cells exhibit enhanced WNT, IGF, and VEGF pathways, promoting epithelial proliferation and vascular remodeling.
Tingwei Chen   +12 more
wiley   +1 more source

Transition From Juvenile Dermatomyositis to Spondyloarthritis: A Novel Overlapping Inflammatory Phenotype

open access: yesACR Open Rheumatology, Volume 8, Issue 3, March 2026.
Objective Juvenile dermatomyositis (JDM) is a rare childhood inflammatory myopathy, whereas spondyloarthritis (SpA) is an inflammatory arthropathy characterized by enthesitis and peripheral or axial involvement. We describe a series of patients diagnosed with JDM in childhood who later fulfilled classification criteria for SpA, a sequential phenotype ...
Austen Grooms   +3 more
wiley   +1 more source

Slow Releasing CO Donor Modulates Susceptibility to Seizures in Rats with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Behavioral and EEG Study. [PDF]

open access: yesMedicina (Kaunas)
Šutulović N   +8 more
europepmc   +1 more source

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