Results 71 to 80 of about 85,519 (312)

Porphyromonas gingivalis in saliva associates with chronic and aggressive periodontitis

Journal of Oral Microbiology, 2019
Objective: To characterize the salivary microbiota of patients with aggressive periodontitis, patients with chronica periodontitis and orally healthy individuals.
Christian Damgaard, Anne Katrine Danielsen, Christian Enevold, Laura Massarenti, Claus Henrik Nielsen, Palle Holmstrup, Daniel Belstrøm   +6 more
doaj   +1 more source

Study on porphyromonas gingivalis- and porphyromonas endodontalis- mediated signaling pathway [PDF]

, 2019
It is known that anaerobic microbes like Porphyromonas gingivalis (P. gingivalis) are involved in the progression and initiation of multiple forms of periodontal disease such as chronic periodontitis.
Alamry, Nujud
core  

Scotland Registry for Ankylosing Spondylitis (SIRAS) – Protocol [PDF]

, 2016
Funding SIRAS was funded by unrestricted grants from Pfizer and AbbVie. The project was reviewed by both companies, during the award process, for Scientific merit, to ensure that the design did not compromise patient safety, and to assess the global ...
Dean, Linda E, Gibson, Jane, Hunter, John, Jones, Elizabeth A, Jones, Gareth T, MacDonald, Alan G, Macfarlane, Gary J, Marshall, David, McEntegart, Anne, Munro, Robin, Sturrock, Roger D   +10 more
core   +1 more source

CHRONIC RENAL FAILURE AND PERIODONTAL DISEASE

Renal Failure, 2000
In order to define the effects of chronic renal failure (CRF) in the progress of gingival inflammation, we studied 6 patients (4 male, 2 female) with CRF who were on chronic hemodialysis for 4.25 (range 1-15) years. Six healthy individuals, age and sex matched were used as controls.
Kitsou, V. K., Konstantinidis, A., Siamopoulos, K. C.   +2 more
openaire   +3 more sources

ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy

Advanced Science, EarlyView.
A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou, Qiming Zhai, Zhihao Yao, Qing Li, Yan Yang, Si Wang, Chao Huang, Liangjing Xin, Tao Chen, Jinlin Song   +9 more
wiley   +1 more source

Association of interleukin-1 α (-889) gene polymorphism in patients with generalized aggressive and chronic periodontitis

Dental Research Journal, 2015
Background: There is a strong evidence that genetic as well as environmental factors affect the age of onset, severity and lifetime risk of developing periodontitis.
Komal Puri, Mehak Chhokra, Vidya Dodwad, Nikhil Puri   +3 more
doaj   +1 more source

Tetracycline Actions Relevant to Rosacea Treatment [PDF]

, 2009
Until today, the pathogenesis of rosacea is not known in detail. Yet in recent years evidence has been accumulating that rosacea with its common symptoms such as inflammatory lesions, erythema, telangiectasia, phymatous changes, and ocular symptoms is of
Korting, Hans Christian, Schöllmann, C.
core   +1 more source

Oral biofilms exposure to chlorhexidine results in altered microbial composition and metabolic profile [PDF]

, 2020
Oral diseases (e.g., dental caries, periodontitis) are developed when the healthy oral microbiome is imbalanced allowing the increase of pathobiont strains.
Boon, Nico, Chatzigiannidou, Ioanna, Teughels, Wim, Van de Wiele, Tom   +3 more
core   +2 more sources

Systemic Immunologic Consequences of Chronic Periodontitis

Journal of Dental Research, 2019
Chronic periodontitis (ChP) is a prevalent inflammatory disease affecting 46% of the US population. ChP produces a profound local inflammatory response to dysbiotic oral microbiota that leads to destruction of alveolar bone and tooth loss. ChP is also associated with systemic illnesses, including cardiovascular diseases, malignancies, and adverse ...
D.K. Gaudilliere, A. Culos, K. Djebali, A.S. Tsai, E.A. Ganio, W.M. Choi, X. Han, A. Maghaireh, B. Choisy, Q. Baca, J.F. Einhaus, J.J. Hedou, B. Bertrand, K. Ando, R. Fallahzadeh, M.S. Ghaemi, R. Okada, N. Stanley, A. Tanada, M. Tingle, T. Alpagot, J.A. Helms, M.S. Angst, N. Aghaeepour, B. Gaudilliere   +24 more
openaire   +4 more sources

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source