Results 91 to 100 of about 85,519 (312)

Expression of hypoxia inducible factor-1α and vascular endothelial growth factor-C in human chronic periodontitis

Journal of Dental Sciences, 2015
Background/purpose: Evidence shows that there is a relationship between hypoxia and inflammatory response in periodontitis. Hypoxia-inducible factor (HIF)-1α is a major regulator of energy homeostasis and cellular adaptation to low oxygen stress ...
Qing-Yan Shi, Shi-Guang Huang, Jing-Hua Zeng, Xiao-Guo Fang   +3 more
doaj   +1 more source

Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]

, 2019
Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio, Di Franco, Manuela, Guzzo, Maria Paola, Iannuccelli, Cristina, Lucchino, Bruno, Spinelli, Francesca Romani   +5 more
core   +1 more source

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, EarlyView.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Single-Cell Enumeration of an Uncultivated TM7 Subgroup in the [PDF]

, 2003
Specific oligonucleotide hybridization conditions were established for single-cell enumeration of uncultivated TM7 and IO25 bacteria by using clones expressing heterologous 16S rRNA. In situ analysis of human subgingival crevice specimens revealed that a
Armitage, Gary C., Ouverney, Cleber C., Relman, David A.   +2 more
core   +1 more source

Oral plaque from Type 2 diabetic patients reduces the clonogenic capacity of dental pulp-derived mesenchymal stem cells [PDF]

, 2019
Type 2 diabetes (T2D) is a major metabolic disease and a key epigenetic risk factor for the development of additional clinical complications. Among them, periodontitis (PD), a severe inflammatory disease ascribable to a dysregulated physiology and ...
Bordin, Antonella, Cavarretta, Elena, Chimenti, Isotta, De Falco, Elena, Incerti, Noemi, Pagano, Francesca, Polimeni, Antonella, Saccucci, Matteo, Scaccia, Eleonora, Vozza, Iole   +9 more
core   +1 more source

Relationship Between Oral Health and Clinical Osteoporosis Among Hospitalized Patients with and Without Diabetes [PDF]

, 2020
Objective: Diabetes mellitus (DM) is associated with poor oral health and osteoporosis (OP). The aim of this study was to assess the relationship between OP, periodontal disease (PD), and other dental and health outcomes in a cohort of hospitalized ...
Allenback, Gayle, Champion, Amber, Gewelber, Civon, Izoura, Kenneth, Neubauer, Michael   +4 more
core   +2 more sources

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Detection of Granulocyte Chemotactic Protein 2 in Serum of Periodontitis Patients

Journal of Baghdad College of Dentistry, 2016
Background: Chronic periodontitis defined as “an infectious inflammatory disease within supporting tissues of the teeth, progressive attachment loss and bone loss".
Saja GH. Hussien, Basima Gh. Ali
doaj   +1 more source

Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis [PDF]

, 2016
BACKGROUND: The linkage between periodontal disease and rheumatoid arthritis is well established. Commonalities among the two are that both are chronic inflammatory diseases characterized by bone loss, an association with the shared epitope ...
Brand, David D, Dong, Chen, Karydis, Anastasios, Luo, Jiwen, Mydel, Piotr, Novack, Deborah V, Prislovsky, Amanda, Radic, Marko Z, Rosloniec, Edward F, Sandal, Indra, Whittington, Karen B, Zheng, Song Guo   +11 more
core   +2 more sources

Intraosseous sarcoidosis imitating peri‐implantitis: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Sarcoidosis is a multisystem granulomatous disorder of unknown cause, typically affecting the lungs and lymph nodes, but it can also involve the eyes, skin, heart, bones, and other organs. The exact cause is unclear, but genetic factors and environmental triggers like infections, chemicals, or dust may play a role.
Magdalena Orlowska, David S. Gottlieb, Kenneth S. Kornman   +2 more
wiley   +1 more source