Hidden density in single-family neighborhoods: Backyard cottages as an equitable smart growth strategy. [PDF]
, 2014 Chronic progressive external ophthalmoplegia (CPEO) is a manifestation of various disorders sharing a common pathophysiology of mitochondrial dysfunction leading to progressive extraocular myopathy.
Wegmann, Jake, Chapple, Karen
core
Eye movement recordings to investigate a supranuclear component in chronic progressive external ophthalmoplegia: a cross-sectional study [PDF]
, 2010 Background It has been postulated that eye movement disorders in chronic progressive external ophthalmoplegia (CPEO) have a neurological as well as a myopathic component to them.
Chinnery, P. F. +3 more
core +1 more source
Mitochondrial Transplantation as a Therapeutic Strategy for Inherited Mitochondrial Diseases
Advanced Science, EarlyView.Mitochondrial transplantation (MTx) offers a promising therapeutic avenue for mitochondrial diseases. This review comprehensively evaluates MTx, differentiating its feasibility for mtDNA‐ and nDNA‐based disorders. It examines its potential for genetic correction, alongside inherent limitations, technical challenges, and crucial ethical considerations ...
Parmeshar Singh +17 more
wiley +1 more source
Assessment of acute headache in adults - what the general physician needs to know. [PDF]
, 2018 Headache is common. Up to 5% of attendances to emergency departments and acute medical units are due to headache. Headache is classified as either primary (eg migraine, cluster headache) or secondary to another cause (eg meningitis, subarachnoid ...
Agrawal +9 more
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Orbital Complications of Acute Rhinosinusitis in Adulthood: Predictors of Outcome and Management
The Laryngoscope, EarlyView.In a multicenter cohort of 213 adults with orbital complications of acute rhinosinusitis, 68% required surgery and the modified Chandler classification was the strongest predictor of treatment modality. While abscess‐related and type II complications frequently necessitated surgical management, final ophthalmologic outcomes were uniformly favorable ...
Alessandro Vinciguerra +41 more
wiley +1 more source
Multi-system neurological disease is common in patients with OPA1 mutations [PDF]
, 1907 Additional neurological features have recently been described in seven families transmitting pathogenic mutations in OPA1, the most common cause of autosomal dominant optic atrophy.
A. Wood +180 more
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Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases [PDF]
, 2009 Neurons are metabolically active cells with high energy demands at locations distant from the cell body. As a result, these cells are particularly dependent on mitochondrial function, as reflected by the observation that diseases of mitochondrial ...
Alexander +42 more
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Chronic progressive external ophthalmoplegia
Acta Ophthalmologica, 2017 SummaryChronic progressive external ophthalmoplegia (CPEO) is a slowly progressive extraocular muscle disorder characterized by bilateral, usually symmetrical, limitation of eye movements and ptosis. This classical manifestation of mitochondrial disease can develop either in isolation or more frequently, in association with other multisystemic features
openaire +1 more source
Postpump Chorea After Pediatric Cardiac Surgery: Exploring Causes and Treatment
Journal of Cardiac Surgery, Volume 2026, Issue 1, 2026.Introduction Postpump chorea is a rare but potentially disabling movement disorder that arises days to weeks after cardiopulmonary bypass, most often following deep hypothermic circulatory arrest in pediatric patients undergoing repair of complex congenital heart defects. Clinically, postpump chorea presents as involuntary, nonrhythmic, choreiform, and
Jad Abdul Khalek +4 more
wiley +1 more source
Chronic intestinal pseudoobstruction and ophthalmoplegia in a patient with mitochondrial myopathy [PDF]
, 1988 A 38 year old woman having chronic intestinal pseudoobstruction associated with mitochondrial myopathy is reported. The clinical and radiographic features suggested the diagnosis of chronic intestinal pseudoobstruction.
Bayés Rusiñol, Àngels +6 more
core +2 more sources