Results 51 to 60 of about 3,957,405 (296)

Chronic neuropathic pain: EEG data in eyes open and eyes closed with painDETECT and brief pain inventory reports

Data in Brief, 2023
Thirty-six chronic neuropathic pain patients (8 men and 28 women) of Mexican nationality with a mean age of 44±13.98 were recruited for EEG signal recording in eyes open and eyes closed resting state condition. Each condition was recorded for 5 min, with
Daniela M. Zolezzi, Norberto E. Naal-Ruiz, Luz María Alonso-Valerdi, David I. Ibarra-Zarate   +3 more
doaj   +1 more source

Electronic Health Records: Cure‐All or Chronic Condition? [PDF]

Global Business and Organizational Excellence, 2014
Computer‐based information systems feature in almost every aspect of our lives, and yet most of us receive handwritten prescriptions when we visit our doctors and rely on paper‐based medical records in our health care. Although electronic health record (EHR) systems have long been promoted as a cost‐effective and efficient alternative to this situation,
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The influence of non-stationarity of spike signals on decoding performance in intracortical brain-computer interface: a simulation study

Frontiers in Computational Neuroscience, 2023
IntroductionIntracortical Brain-Computer Interfaces (iBCI) establish a new pathway to restore motor functions in individuals with paralysis by interfacing directly with the brain to translate movement intention into action.
Zijun Wan, Zijun Wan, Tengjun Liu, Tengjun Liu, Xingchen Ran, Xingchen Ran, Pengfu Liu, Pengfu Liu, Weidong Chen, Weidong Chen, Shaomin Zhang, Shaomin Zhang   +11 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A self-insertable 5-μm-diameter flexible microneedle for minimally invasive and stable in vivo neural recording

Sensing and Bio-Sensing Research
Implantable intracortical microelectrodes are essential tools for neuroscience research, clinical applications, and brain–computer interfaces. Achieving stable chronic recording of neuronal activity, however, remains challenging due to tissue damage ...
Hinata Sasaki, Sayaki Shimizu, Rexy Alvian Nerchan, Koji Yamashita, Naohiro Takahashi, Rina Chinone, Yurika Kurashige, Rika Numano, Kowa Koida, Masahiro Ohsawa, Takeshi Kawano   +10 more
doaj   +1 more source

Micro-drive and headgear for chronic implant and recovery of optoelectronic probes

Scientific Reports, 2017
Silicon probes are multisite electrodes used for the electrophysiological recording of large neuronal ensembles. Optoelectronic probes (OEPs) are recent upgrades that allow, in parallel, the delivery of local optical stimuli.
Jinho Chung, Farnaz Sharif, Dajung Jung, Soyoun Kim, Sebastien Royer   +4 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source