Results 1 to 10 of about 579,871 (293)

Concurrent IgA Nephropathy and Membranous Nephropathy, Is It an Overlap Syndrome?

open access: yesFrontiers in Immunology, 2022
IgA nephropathy (IgAN) and membranous nephropathy (MN) are common glomerulonephritis, the presence of which in the same patient– concurrent of IgAN and MN (cIgAN/MN) has been described occasionally.
Jia-Wei He   +13 more
doaj   +1 more source

A Functional Variant rs3093023 in CCR6 Is Associated With IgA Nephropathy by Regulating Th17 Cells in a North Han Chinese Population

open access: yesFrontiers in Immunology, 2021
C-C chemokine receptor 6 (CCR6) is a susceptibility gene of various immune-related diseases, which was suggested to be shared with immunoglobulin A nephropathy (IgAN). In this study, we aimed to identify the functional variants.
Yue-miao Zhang   +23 more
doaj   +1 more source

Elevation of erythrocyte sedimentation rate and C-reactive protein levels reflects renal interstitial inflammation in drug-induced acute tubulointerstitial nephritis

open access: yesBMC Nephrology, 2020
Background A renal biopsy is needed to define active inflammatory infiltration and guide therapeutic management in drug-induced acute tubulointerstitial nephritis (D-ATIN).
Xi-zi Zheng   +10 more
doaj   +1 more source

Weighted Gene Co-expression Network Analysis Reveals Different Immunity but Shared Renal Pathology Between IgA Nephropathy and Lupus Nephritis

open access: yesFrontiers in Genetics, 2021
Both IgA nephropathy (IgAN) and lupus nephritis (LN) are immunity-related diseases with a complex, polygenic, and pleiotropic genetic architecture. However, the mechanism by which the genetic variants impart immunity or renal dysfunction remains to be ...
Ni-Ya Jia   +11 more
doaj   +1 more source

Effect of hydroxychloroquine in patients with IgA nephropathy with insufficient responses to immunosuppressive therapy: a retrospective case-control study

open access: yesBMC Nephrology, 2020
Background Hydroxychloroquine (HCQ) is a well-known immunomodulator that was recently used in immunoglobulin A (IgA) nephropathy (IgAN) due to its antiproteinuric effects.
Chen Tang   +5 more
doaj   +1 more source

Atypical Hemolytic Uremic Syndrome-Associated FHR1 Isoform FHR1*B Enhances Complement Activation and Inflammation

open access: yesFrontiers in Immunology, 2022
Atypical hemolytic uremic syndrome (aHUS) is a rare but severe type of thrombotic microangiopathy that is triggered by the abnormal activation of the alternative complement pathway.
Boyang Xu   +5 more
doaj   +1 more source

Plasma Homocysteine as a Potential Marker of Early Renal Function Decline in IgA Nephropathy

open access: yesFrontiers in Medicine, 2022
Hyperhomocysteinemia (HHcy) is very common among patients with chronic kidney disease (CKD), and related to the risk of cardiovascular events and mortality in these patients. However, the prevalence of HHcy in primary causes of CKD and its role in kidney
Yan-Na Wang   +16 more
doaj   +1 more source

Rituximab Therapy for Primary Membranous Nephropathy in a Chinese Cohort

open access: yesFrontiers in Medicine, 2021
Background: Rituximab has become one of the first-line therapies for the treatment of moderate and high-risk primary membranous nephropathy (pMN).
Shuang Gao   +40 more
doaj   +1 more source

An Updated Review and Meta Analysis of Lipoprotein Glomerulopathy

open access: yesFrontiers in Medicine, 2022
More than 200 cases of lipoprotein glomerulopathy (LPG) have been reported since it was first discovered 30 years ago. Although relatively rare, LPG is clinically an important cause of nephrotic syndrome and end-stage renal disease. Mutations in the APOE
Meng-shi Li   +19 more
doaj   +1 more source

Homocysteine and IgA nephropathy: observational and Mendelian randomization analyses

open access: yesChinese Medical Journal, 2020
. Background:. High levels of plasma homocysteine occur almost uniformly in patients with end-stage renal disease (ESRD). IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and a common cause of ESRD in young adults.
Yue-Miao Zhang   +6 more
doaj   +1 more source

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