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Concurrent IgA Nephropathy and Membranous Nephropathy, Is It an Overlap Syndrome?
IgA nephropathy (IgAN) and membranous nephropathy (MN) are common glomerulonephritis, the presence of which in the same patient– concurrent of IgAN and MN (cIgAN/MN) has been described occasionally.
Jia-Wei He+13 more
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C-C chemokine receptor 6 (CCR6) is a susceptibility gene of various immune-related diseases, which was suggested to be shared with immunoglobulin A nephropathy (IgAN). In this study, we aimed to identify the functional variants.
Yue-miao Zhang+23 more
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Background A renal biopsy is needed to define active inflammatory infiltration and guide therapeutic management in drug-induced acute tubulointerstitial nephritis (D-ATIN).
Xi-zi Zheng+10 more
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Both IgA nephropathy (IgAN) and lupus nephritis (LN) are immunity-related diseases with a complex, polygenic, and pleiotropic genetic architecture. However, the mechanism by which the genetic variants impart immunity or renal dysfunction remains to be ...
Ni-Ya Jia+11 more
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Background Hydroxychloroquine (HCQ) is a well-known immunomodulator that was recently used in immunoglobulin A (IgA) nephropathy (IgAN) due to its antiproteinuric effects.
Chen Tang+5 more
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Atypical hemolytic uremic syndrome (aHUS) is a rare but severe type of thrombotic microangiopathy that is triggered by the abnormal activation of the alternative complement pathway.
Boyang Xu+5 more
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Plasma Homocysteine as a Potential Marker of Early Renal Function Decline in IgA Nephropathy
Hyperhomocysteinemia (HHcy) is very common among patients with chronic kidney disease (CKD), and related to the risk of cardiovascular events and mortality in these patients. However, the prevalence of HHcy in primary causes of CKD and its role in kidney
Yan-Na Wang+16 more
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Rituximab Therapy for Primary Membranous Nephropathy in a Chinese Cohort
Background: Rituximab has become one of the first-line therapies for the treatment of moderate and high-risk primary membranous nephropathy (pMN).
Shuang Gao+40 more
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An Updated Review and Meta Analysis of Lipoprotein Glomerulopathy
More than 200 cases of lipoprotein glomerulopathy (LPG) have been reported since it was first discovered 30 years ago. Although relatively rare, LPG is clinically an important cause of nephrotic syndrome and end-stage renal disease. Mutations in the APOE
Meng-shi Li+19 more
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Homocysteine and IgA nephropathy: observational and Mendelian randomization analyses
. Background:. High levels of plasma homocysteine occur almost uniformly in patients with end-stage renal disease (ESRD). IgA nephropathy (IgAN) is the most common form of primary glomerulonephritis and a common cause of ESRD in young adults.
Yue-Miao Zhang+6 more
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