Results 21 to 30 of about 7,324,613 (292)
Renal AA-amyloidosis in intravenous drug users - a role for HIV-infection? [PDF]
, 2012 Background: Chronic renal disease is a serious complication of long-term intravenous drug use (IVDU). Recent reports have postulated a changing pattern of underlying nephropathy over the last decades.
Grützmacher, Peter +17 more
core +2 more sources
Potential Involvement of Complement Activation in Kidney Vascular Lesions of Arterionephrosclerosis
Frontiers in Medicine, 2022 BackgroundComplement dysregulation has been implicated in the pathogenesis of malignant nephrosclerosis with typical pathological manifestation as thrombotic microangiopathy (TMA) in recent studies.
Xuejing Chen +6 more
doaj +1 more source
ADTKD-UMOD in a girl with a de novo mutation: A case report
Frontiers in Medicine, 2022 Autosomal dominant tubulointerstitial kidney disease due to UMOD mutations (ADTKD-UMOD) is a rare condition associated with high variability in the age of end-stage kidney disease (ESKD). An autosomal dominant inheritance is the general rule, but de novo
Meng-shi Li +36 more
doaj +1 more source
Kidney disease management in UK primary care: guidelines, incentives and Information Technology [PDF]
, 2007 The last few years have seen new developments to understand and tackle the significant public health issue posed by chronic kidney disease (CKD). Established renal disease currently consumes 2% of the UK National Health Service budget and predictions are
Cooley, R +15 more
core +1 more source
Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL
Journal of Immunology Research, 2015 Objectives. Numerous loci were identified to perturb gene expression in trans. As elevated ATG5 expression was observed in systemic lupus erythematosus (SLE), the study was conducted to analyze the genome-wide genetic regulatory mechanisms associated ...
Yue-miao Zhang +6 more
doaj +1 more source
BMC Nephrology, 2019 Background Hemophagocytic lymphohistiocytosis (HLH) is characterized by excessive activation of the immune system due to infection, autoimmune diseases, or malignancy.
Bixia Gao +3 more
doaj +1 more source
Kidney Medicine, 2021 Background: Glomerular deposition of C4d is a widely used biomarker for activation of the lectin pathway in the complement system and is reported to be associated with kidney progression in immunoglobulin A nephropathy (IgAN).
Yuanyuan Jiang +8 more
doaj +1 more source
Murine models of renal disease: Possibilities and problems in studies using mutant mice [PDF]
, 2000 The elucidation of the pathogenesis of human renal disease at the molecular level has been facilitated by the growing field of gene targeting and the development of mouse strains with single-gene deletions - the `knock-out' mice. Experimental nephrology,
Anders, Hans-Joachim +1 more
core +1 more source
Journal of Translational Medicine, 2020 Background The association between blood pressure change and kidney damage in patients with abnormal blood glucose remains unclear. The current study aimed to identify systolic blood pressure (SBP) trajectories among the prediabetic population and to ...
Zi-Jun Sun +9 more
doaj +1 more source
Patient access to complex chronic disease records on the internet [PDF]
, 2012 Background: Access to medical records on the Internet has been reported to be acceptable and popular with patients, although most published evaluations have been of primary care or office-based practice.
Bartlett, C. +9 more
core +2 more sources