Results 111 to 120 of about 579,871 (293)
Stem Cell Research, 2021 Bardet-Biedl syndrome (BBS) is primarily a multisystem nonmotile ciliopathy. In this study, we describe the successful establishment and characterization of an iPSC line from a patient diagnosed with BBS who was compound heterozygous for the BBS7 ...
Qian Fu +6 more
doaj
High Frequency Hearing Loss in Chronic Renal Disease: A Cross-Sectional Study. [PDF]
Indian J Otolaryngol Head Neck Surg, 2022 Sarin V, Sharma A, Chopra I.
europepmc +1 more source
Enhancing End Stage Renal Disease Outcome Prediction: A Multi-Sourced Data-Driven Approach [PDF]
arXivObjective: To improve prediction of Chronic Kidney Disease (CKD) progression to End Stage Renal Disease (ESRD) using machine learning (ML) and deep learning (DL) models applied to an integrated clinical and claims dataset of varying observation windows, supported by explainable AI (XAI) to enhance interpretability and reduce bias.
arxiv
NF2 is Essential for Human Endoderm Development
Advanced Science, EarlyView.This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong +5 more
wiley +1 more source
Current status of liver transplantation for non‐B non‐C liver cirrhosis and hepatocellular carcinoma
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 42-52, January 2023., 2023 Recently, the cases of LT for non‐B non‐C cirrhosis and HCC have been increasing in Japan as well as worldwide. Perioperative management of non‐B non‐C liver disease is problematic due to various risk factors, including alcohol consumption and metabolic syndrome‐related risks, such as obesity and diabetes mellitus.
Takahiro Nishio +4 more
wiley +1 more source
Sudden cardiac death in chronic renal disease: aetiology and risk reduction strategies. [PDF]
Nephrol Dial Transplant, 2021 Pickup LC, Law JP, Townend JN, Ferro CJ.
europepmc +1 more source
Towards Interpretable End-Stage Renal Disease (ESRD) Prediction: Utilizing Administrative Claims Data with Explainable AI Techniques [PDF]
arXivThis study explores the potential of utilizing administrative claims data, combined with advanced machine learning and deep learning techniques, to predict the progression of Chronic Kidney Disease (CKD) to End-Stage Renal Disease (ESRD). We analyze a comprehensive, 10-year dataset provided by a major health insurance organization to develop prediction
arxiv
Metabolism in immunoreactive parathyroid hormone in the dog. The role of the kidney and the effects of chronic renal disease. [PDF]
, 1975 Keith A. Hruska +7 more
openalex +1 more source
Advanced Science, EarlyView.Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang +12 more
wiley +1 more source
Annals of Gastroenterological Surgery, Volume 7, Issue 1, Page 157-166, January 2023., 2023 For radical surgery after induction gemcitabine along with nab‐paclitaxel and subsequent chemoradiotherapy for unresectable locally advanced pancreatic ductal adenocarcinoma, CA19‐9 normalization and maintenance of good nutritional status during treatment until surgery were important for prolonged prognosis.
Takamichi Igarashi +9 more
wiley +1 more source