Results 21 to 30 of about 579,871 (293)

Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL

open access: yesJournal of Immunology Research, 2015
Objectives. Numerous loci were identified to perturb gene expression in trans. As elevated ATG5 expression was observed in systemic lupus erythematosus (SLE), the study was conducted to analyze the genome-wide genetic regulatory mechanisms associated ...
Yue-miao Zhang   +6 more
doaj   +1 more source

Acute oxalate nephropathy: A potential cause of acute kidney injury in diabetes mellitus—A case series from a single center

open access: yesFrontiers in Medicine, 2022
BackgroundAcute oxalate nephropathy (AON) is an uncommon condition that causes acute kidney injury (AKI), characterized by the massive deposition of calcium oxalate crystals in the renal parenchyma. In previous studies, urinary oxalate excretion has been
Daorina Bao   +5 more
doaj   +1 more source

Renal Expression of Annexin A1 Is Associated With the Severity of Renal Injury in Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis

open access: yesFrontiers in Medicine, 2022
BackgroundIncreasing studies demonstrated the importance of activation of neutrophils in the pathogenesis of antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV).
Rui-Xue Wang   +26 more
doaj   +1 more source

Q fever outbreak in the terraced vineyards of Lavaux, Switzerland

open access: yesNew Microbes and New Infections, EarlyView., 2014
Abstract Coxiella burnetii infection (Q fever) is a widespread zoonosis with low endemicity in Switzerland, therefore no mandatory public report was required. A cluster of initially ten human cases of acute Q fever infections characterized by prolonged fever, asthenia and mild hepatitis occurred in 2012 in the terraced vineyard of Lavaux ...
C. Bellini   +9 more
wiley   +1 more source

MEDIMP: 3D Medical Images with clinical Prompts from limited tabular data for renal transplantation [PDF]

open access: yesarXiv, 2023
Renal transplantation emerges as the most effective solution for end-stage renal disease. Occurring from complex causes, a substantial risk of transplant chronic dysfunction persists and may lead to graft loss. Medical imaging plays a substantial role in renal transplant monitoring in clinical practice. However, graft supervision is multi-disciplinary,
arxiv  

A modified renal risk score for Chinese patients with antineutrophil cytoplasmic antibody-associated vasculitis

open access: yesBMC Medicine, 2023
Background The renal risk score (RRS) is a useful tool to predict end-stage renal disease (ESRD) in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).
Rui-Xue Wang   +11 more
doaj   +1 more source

Segmentation of diagnostic tissue compartments on whole slide images with renal thrombotic microangiopathies (TMAs) [PDF]

open access: yesarXiv, 2023
The thrombotic microangiopathies (TMAs) manifest in renal biopsy histology with a broad spectrum of acute and chronic findings. Precise diagnostic criteria for a renal biopsy diagnosis of TMA are missing. As a first step towards a machine learning- and computer vision-based analysis of wholes slide images from renal biopsies, we trained a segmentation ...
arxiv  

Reduction in Serum High-Sensitivity C-Reactive Protein Favors Kidney Outcomes in Patients with Impaired Fasting Glucose or Diabetes

open access: yesJournal of Diabetes Research, 2020
Objective. We aimed to evaluate whether the reduction in serum high-sensitivity C-reactive protein (hs-CRP) favors kidney outcomes. Methods. This study was a subanalysis including patients with impaired fasting glucose or diabetes of the Kailuan cohort ...
Lili Liu   +12 more
doaj   +1 more source

Machine learning for dynamically predicting the onset of renal replacement therapy in chronic kidney disease patients using claims data [PDF]

open access: yesarXiv, 2022
Chronic kidney disease (CKD) represents a slowly progressive disorder that can eventually require renal replacement therapy (RRT) including dialysis or renal transplantation. Early identification of patients who will require RRT (as much as 1 year in advance) improves patient outcomes, for example by allowing higher-quality vascular access for dialysis.
arxiv  

Complement Activation Is Associated With Crescents in IgA Nephropathy

open access: yesFrontiers in Immunology, 2021
IntroductionCrescents, especially those found at a percentage greater than 50%, are often associated with rapid progression of kidney disease in IgA nephropathy (IgAN). The mechanism of crescents forming in IgAN is still unclear.
Zi Wang   +23 more
doaj   +1 more source

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