Results 21 to 30 of about 1,099,815 (209)
Background: Glomerular deposition of C4d is a widely used biomarker for activation of the lectin pathway in the complement system and is reported to be associated with kidney progression in immunoglobulin A nephropathy (IgAN).
Yuanyuan Jiang +8 more
doaj +1 more source
Hypertension Treatment for Patients with Advanced Chronic Kidney Disease [PDF]
Chronic kidney disease is common and frequently complicated with hypertension. As a major modifiable risk factor for cardiovascular disease in this high risk population, treatment of hypertension in chronic kidney disease is of paramount importance.
Agarwal, Rajiv, Sinha, Arjun D.
core +1 more source
Risk prediction to inform surveillance of chronic kidney disease in the US Healthcare Safety Net: a cohort study. [PDF]
BackgroundThe capacity of electronic health record (EHR) data to guide targeted surveillance in chronic kidney disease (CKD) is unclear. We sought to leverage EHR data for predicting risk of progressing from CKD to end-stage renal disease (ESRD) to help ...
Chertow, Glenn M +5 more
core +2 more sources
Background Hemophagocytic lymphohistiocytosis (HLH) is characterized by excessive activation of the immune system due to infection, autoimmune diseases, or malignancy.
Bixia Gao +3 more
doaj +1 more source
Biological Pathways and Potential Targets for Prevention and Therapy of Chronic Allograft Nephropathy [PDF]
Renal transplantation (RT) is the best option for patients with end-stage renal disease, but the half-life is limited to a decade due to progressive deterioration of renal function and transplant failure from chronic allograft nephropathy (CAN), which is
Haylor, John, Shrestha, Badri Man
core +3 more sources
Renal function assessment in adults with recurrent calcium kidney stone disease [PDF]
The prevalence of nephrolihiasis and chronic kidney disease has risen over the past three decades, we sought to determine if person with a history of kidney stones have lower renal function relative to non stone formers.
Milladipour, Amir Hossein +1 more
core +1 more source
Detecting Genetic Associations between ATG5 and Lupus Nephritis by trans-eQTL
Objectives. Numerous loci were identified to perturb gene expression in trans. As elevated ATG5 expression was observed in systemic lupus erythematosus (SLE), the study was conducted to analyze the genome-wide genetic regulatory mechanisms associated ...
Yue-miao Zhang +6 more
doaj +1 more source
Background The association between blood pressure change and kidney damage in patients with abnormal blood glucose remains unclear. The current study aimed to identify systolic blood pressure (SBP) trajectories among the prediabetic population and to ...
Zi-Jun Sun +9 more
doaj +1 more source
BackgroundAcute oxalate nephropathy (AON) is an uncommon condition that causes acute kidney injury (AKI), characterized by the massive deposition of calcium oxalate crystals in the renal parenchyma. In previous studies, urinary oxalate excretion has been
Daorina Bao +5 more
doaj +1 more source
Benefit of Apabetalone on Plasma Proteins in Renal Disease. [PDF]
Introduction:Apabetalone, a small molecule inhibitor, targets epigenetic readers termed BET proteins that contribute to gene dysregulation in human disorders. Apabetalone has in vitro and in vivo anti-inflammatory and antiatherosclerotic properties.
Gilham, Dean +11 more
core +2 more sources

