Renal Parenchymal Area and Kidney Collagen Content [PDF]
The extent of renal scarring in chronic kidney disease (CKD) can only be ascertained by highly invasive, painful and sometimes risky tissue biopsy. Interestingly, CKD-related abnormalities in kidney size can often be visualized using ultrasound. Nevertheless, not only does the ellipsoid formula used today underestimate true renal size but also the ...
arxiv
Arterial stiffening provides sufficient explanation for primary hypertension [PDF]
Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite intense research efforts over many decades.
arxiv +1 more source
Assessment of concurrent neoplasms and a paraneoplastic association in MOGAD
Abstract Cases of myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) co‐occurring with neoplasms have been reported. In this international, retrospective cohort study in South Korea and the USA, 16 of 445 (3.6%) patients with MOGAD had concurrent neoplasm within 2 years of MOGAD onset, resulting in a standardized incidence ...
Young Nam Kwon+24 more
wiley +1 more source
Background: Glomerular deposition of C4d is a widely used biomarker for activation of the lectin pathway in the complement system and is reported to be associated with kidney progression in immunoglobulin A nephropathy (IgAN).
Yuanyuan Jiang+8 more
doaj
Using Soft Computer Techniques on Smart Devices for Monitoring Chronic Diseases: the CHRONIOUS case [PDF]
CHRONIOUS is an Open, Ubiquitous and Adaptive Chronic Disease Management Platform for Chronic Obstructive Pulmonary Disease(COPD) Chronic Kidney Disease (CKD) and Renal Insufficiency. It consists of several modules: an ontology based literature search engine, a rule based decision support system, remote sensors interacting with lifestyle interfaces ...
arxiv
Clinical Phenotyping of Long COVID Patients Evaluated in a Specialized Neuro‐COVID Clinic
ABSTRACT Objective To report Long COVID characteristics and longitudinal courses of patients evaluated between 4/14/21–4/14/22 at the University of Pennsylvania Neurological COVID Clinic (PNCC), including clinical symptoms, neurological examination findings, and neurocognitive screening tests from a standardized PNCC neurological evaluation approach ...
Luana D. Yamashita+7 more
wiley +1 more source
Home‐Based Tele‐tDCS in Amyotrophic Lateral Sclerosis: Feasibility, Safety, and Preliminary Efficacy
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with limited treatment options. Transcranial direct current stimulation (tDCS) shows promise as a neuromodulatory intervention in various neurological disorders, but its application in ALS, particularly in a remote, home‐based format, remains underexplored.
Sangeetha Madhavan+6 more
wiley +1 more source
Can an Ad-hoc ontology Beat a Medical Search Engine? The Chronious Search Engine case [PDF]
Chronious is an Open, Ubiquitous and Adaptive Chronic Disease Management Platform for Chronic Obstructive Pulmonary Disease(COPD) Chronic Kidney Disease (CKD) and Renal Insufficiency. It consists of several modules: an ontology based literature search engine, a rule based decision support system, remote sensors interacting with lifestyle interfaces ...
arxiv
Sparse Longitudinal Representations of Electronic Health Record Data for the Early Detection of Chronic Kidney Disease in Diabetic Patients [PDF]
Chronic kidney disease (CKD) is a gradual loss of renal function over time, and it increases the risk of mortality, decreased quality of life, as well as serious complications. The prevalence of CKD has been increasing in the last couple of decades, which is partly due to the increased prevalence of diabetes and hypertension.
arxiv
Objective This work aimed to evaluate the pharmacokinetics, efficacy, and safety of upadacitinib, an oral selective JAK inhibitor, in pediatric patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods In an open‐label, phase 1 study (SELECT‐YOUTH), enrolled patients, aged 2 to <18 years with pcJIA, received body weight–based ...
Hermine I. Brunner+12 more
wiley +1 more source