Results 111 to 120 of about 1,128,531 (391)

Ammonia Dynamics in the Human Body: Insights in Biomedical Sensing Technologies

Advanced Sensor Research, EarlyView.
Ammonia (NH3) is a significant biomarker in diagnostics, affecting the respiratory system, stomach, liver, kidneys, bladder, and gastrointestinal tract. NH3 detection, using sensors, has the potential to improve medical diagnosis. This review examines recent advancements in NH3 sensing technologies and explores future research directions, including ...
Annelot Nijkoops, Manuela Ciocca, Martina Aurora Costa Angeli, Silvia Pogliaghi, Soufiane Krik, Enrico Avancini, Niko Münzenrieder, Paolo Lugli, Luisa Petti   +8 more
wiley   +1 more source

Effect of L-carnitine on lipid biomarkers of oxidative stress in chronic hemodialysis patients: a randomized controlled trial

Gazi Medical Journal
Objective: This clinical trial aimed to evaluate the effect of L-carnitine on serum levels of lipid biomarkers of oxidative stress in chronic hemodialysis patients.
Shokoh Shayanpour, Seyyed Seyfollah Beladi Mousavi, Hossain Karimpourian, Khojasteh Hoseinynejad, Kambiz Ahmadi Angali   +4 more
doaj   +1 more source

Features of prevention of chronic kidney diseases and chronic heart failure [PDF]

, 2023
Chronic renal failure (CRF) is a gradual deterioration of kidney function over a long period of time. In modern literature, the term "chronic kidney disease" is found, which has a somewhat broader meaning and implies a decrease in kidney function for ...
Khaydarov, Sanjar Nizamitdinovich, Khusainova, Munira Alisherovna, Makhmudova, Khanuza Davranovna, Ortikova, Sohiba Xamroyevna   +3 more
core   +1 more source

The metabolic fate of vitamin D3-3H in chronic renal failure.

Journal of Clinical Investigation, 1968
The absorption and metabolism of vitamin D(3)-(3)H was studied in eight patients with chronic renal failure. Although the intestinal absorption of vitamin D(3)-(3)H was normal, the metabolic fate of the vitamin was abnormal as characterized by a twofold ...
L. Avioli, S. Birge, S. W. Lee, E. Slatopolsky   +3 more
semanticscholar   +1 more source

Inhibition of Aberrant Activated Fibroblast‐Like Synoviocytes in Rheumatoid Arthritis by Leishmania Peptide via the Regulation of Fatty Acid Synthesis Metabolism

Advanced Science, EarlyView.
LACK156‐173 is internalized into RA‐FLSs via CAPN2‐mediated endocytosis and inhibits the aggressive phenotype of RA‐FLSs by restoring dysregulated fatty acid synthesis metabolism mediated by overexpressed FASN. The findings suggest that targeting the restoration of fatty acid metabolism could potentially alleviate synovial invasion and joint damage in ...
Jianling Su, Xuemei Fan, Yaoyao Zou, Guangtao Fu, Shiqi Feng, Xiaoxue Wang, Yongmei Yu, Lin Li, Zhenhua Bian, Rongrong Huang, Linmang Qin, Jiping Chen, Qin Zeng, Kai Yan, Caiyue Gao, Zhexiong Lian, Xin Li, Yang Li   +17 more
wiley   +1 more source

HAEMODIALYSIS IN B. P. KOIRALA INSTITUTE OF HEALTH SCIENCES, DHARAN - AN INITIAL EXPERIENCE

Journal of Nepal Medical Association, 2003
Dialysis supports life, in spite of complete cessation of renal functions. Haemodialysis (HD) service became available in B. P. Koirala Institute of Health Sciences, Dharan since September 1999.
Sanjib Kumar Sharma, P Kumar, A Chapagain, S Koirala   +3 more
doaj   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source

Clinical overview on RASopathies

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, Volume 190, Issue 4, Page 414-424, December 2022., 2022
Abstract RASopathies comprise a group of clinically overlapping developmental disorders caused by genetic variations affecting components or modulators of the RAS‐MAPK signaling cascade, which lead to dysregulation of signal flow through this pathway.
Martin Zenker
wiley   +1 more source

Contractile responses of urinary bladder in an experimental model of chronic renal failure

Biomolecules & Biomedicine, 2012
Chronic kidney disease is a public health problem with increasing prevalence caused by diabetes, hypertension and glomerulonephritis. Number of publications investigate the lower urinary tract dysfunction due to CKD is limited.
Hüseyin Biçer, Esat Korgali, Gökhan Gökçe, Semih Ayan, Şahin Yıldırım, E. Yener Gültekin   +5 more
doaj   +1 more source

NF2 is Essential for Human Endoderm Development

Advanced Science, EarlyView.
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong, Dongjun Han, Preetida Bhetariya, D. Bradley Welling, Miodrag Stojkovic, Konstantina M. Stankovic   +5 more
wiley   +1 more source