Results 181 to 190 of about 439,363 (315)

A study of biochemical profile of chronic renal failure patients in tertiary care hospital: a cross sectional study

, 2015
Mehul Kaliya, Mittal Rathod, Aniruddha Gohel, Ajay Tanna, Minesh P. Mehta   +4 more
openalex   +2 more sources

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source

Immune Reconstitution After Total Parathyroidectomy and Forearm Transplantation in Chronic Renal Failure. [PDF]

J Craniofac Surg
Ren T, Zhong T, Yang F, Liao X, Yang M, Ji L, Guo Z, Huang J.   +7 more
europepmc   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

WCN24-651 PREVALENCE OF STAGE 3-5 CHRONIC KIDNEY DISEASE IN A FRENCH PACIFIC REMOTE ISLAND (NEW CALEDONIA)

Kidney International Reports
Jean-François CANTIN, ELODIE MAGNAT, MARINA CAUCHY, RAPHAEL COHEN, NOEMIE BAROUX, PASCALE DOMINGUE MENA   +5 more
doaj   +1 more source

Plasma brain-derived neurotrophic factor before hemodialysis reduces the risk of depression in patients with chronic renal failure. [PDF]

Ren Fail
Suárez-Cuenca JA, Campos-Nolasco NP, Rodríguez-Ayala E, Zepeda-Làmbarry AD, Ochoa-Madrigal MG, Maldonado-Tapia D, Vera-Gómez E, Hernández-Patricio A, Martínez-Torres G, Bernal-Figueroa Y, Pineda-Juárez JA, Gutiérrez-Salinas J, Toledo-Lozano CG, García S.   +13 more
europepmc   +1 more source

Effects of canagliflozin on cardiovascular, renal, and safety outcomes in participants with type 2 diabetes and chronic kidney disease according to history of heart failure: Results from the CREDENCE trial

, 2020
Ashish Sarraju, Jingwei Li, Christopher P. Cannon, Tara I. Chang, Rajiv Agarwal, George L. Bakris, David M. Charytan, Dick de Zeeuw, Tom Greene, Hiddo J.L. Heerspink, Adeera Levin, Bruce Neal, Carol A. Pollock, David C. Wheeler, Yshai Yavin, Hong Zhang, Bernard Zinman, Vlado Perkovic, Meg Jardine, Kenneth W. Mahaffey   +19 more
openalex   +2 more sources

Elevation Of Antithrombin III By Sulfinpyrazone Therapy In Chronic Renal Failure [PDF]

, 1981
Murray M. Bern, J Green
openalex   +1 more source

Macrophage‐Targeted Magnesium Ion‐Nourisher for NLRP3 Inflammasome Inhibition to Enhance Liver Inflammatory Disease Treatment

Advanced Science, EarlyView.
This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang, Zhuo Yan, Sindhu Yalavarthi, Yusif Abdul‐Rashid, Kiki Parker, Kyle Nowlin, Ethan Li, Jordan Mack, Josephine Wei, Hunter Vu, Zhenquan Jia, Jianjun Wei, Jilong Wang, Kerui Wu   +13 more
wiley   +1 more source

Association between hemodialysis and surgical outcomes of pars plana vitrectomy in patients with chronic renal failure and proliferative diabetic retinopathy: a retrospective analysis. [PDF]

Eur J Med Res
Wang Y, Hao M, Kong X, Zhao S, Ma S, Zhou W.   +5 more
europepmc   +1 more source