Results 211 to 220 of about 739,236 (344)

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Measurement of serum adropin levels in chronic renal failure patients receiving routine hemodialysis treatment. [PDF]

Medicine (Baltimore)
Kiliç AF, Erkuş E, Duysak L.
europepmc   +1 more source

Efficacy of oral roxadustat combined with L-carnitine for dialysis-induced anemia in patients with chronic renal failure

Chun Zhang, Liutong Shang, Lianqing An, Wei Liu, Yajun Zhang, Zhenjiang Liu   +5 more
openalex   +2 more sources

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

WCN24-651 PREVALENCE OF STAGE 3-5 CHRONIC KIDNEY DISEASE IN A FRENCH PACIFIC REMOTE ISLAND (NEW CALEDONIA)

Kidney International Reports
Jean-François CANTIN, ELODIE MAGNAT, MARINA CAUCHY, RAPHAEL COHEN, NOEMIE BAROUX, PASCALE DOMINGUE MENA   +5 more
doaj   +1 more source

Unveiling the material basis of Shenshuaifu granule and its therapeutic mechanism in chronic renal failure: a combined approach of high-resolution mass spectrometry and <i>in silico</i> technology. [PDF]

Front Chem
Huang Q, Xian L, Song X, Zou D, Chen J, Chen Y, Li W, Zhang S, Liang H.   +8 more
europepmc   +1 more source

Assessment of serum biomarkers of oxidative stress in patients with chronic renal failure

, 2017
Sarala Devi Tenepalli, Karunasree Yerrajwala   +1 more
openalex   +1 more source

Effect of Chitosan on Renal Function in Patients with Chronic Renal Failure [PDF]

, 1997
Shi-Bing JING, LI Leishi, Daxi Ji, Yasuyuki Takiguchi, Tatsuaki Yamaguchi   +4 more
openalex   +1 more source

An Engineered Solidified Peptide Hemocyte Sponge as Nanomotor Storage to Combat Bacterial Colitis

Advanced Science, EarlyView.
Peptides immobilized via nickel coordination can stabilize the framework structure. Following coating with red blood cell membranes, these constructs are capable of continuously sequestering endotoxins and mitigating colonic pathogenic damage by alleviating bacterial‐induced ferroptosis.
Yuxin Fang, Jianming Yan, Tongxin Yu, Zichuan An, Kaikai Lv, Chenyu Xue, Hongyang Yu, Na Dong, Anshan Shan   +8 more
wiley   +1 more source