Results 241 to 250 of about 739,236 (344)

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

A Case of Acquired Cystic Kidney Disease From Chronic Renal Failure Without Dialysis. [PDF]

Cureus
Chiu B, Diaz I, Quintero E, Bedran K.
europepmc   +1 more source

Serum erythropoietin levels and inhibitors of erythropoiesis in patients with chronic renal failure.

, 1986
Y Fukushima, Mitsuyuki Fukuda, Kôsaku Yoshida, Akihiko Yamaguchi, Yasushi Nakamoto, Akira Miura, Tadashi Harada, Seigi Tsuchida   +7 more
openalex   +2 more sources

Magnetoelectric Nanotherapy Achieves Complete Tumor Ablation and Prolonged Survival in Pancreatic Cancer Murine Models

Advanced Science, EarlyView.
Magnetoelectric nanoparticles (MENPs) serve as externally controlled, MRI‐activated theranostic agents for targeted cancer therapy by inducing electric field‐based ablation in solid tumors. MENPs enable simultaneous precise tumor ablation and MRI signal modulation, allowing real‐time treatment monitoring and prediction of therapeutic outcomes with no ...
John Michael Bryant, Max Shotbolt, Emmanuel Stimphil, Victoria Andre, Elric Zhang, Veronica Estrella, Kazim Husain, Joseph Weygand, Doug Marchion, Alex Sebastian Lopez, Dominique Abrahams, Shawnus Chen, Mostafa Abdel‐Mottaleb, Skye Conlan, Ibrahim Oraiqat, Vaseem Khatri, Jose Alejandro Guevara, Shari Pilon‐Thomas, Gage Redler, Kujtim Latifi, Natarajan Raghunand, Kosj Yamoah, Sarah Hoffe, James Costello, Jessica M. Frakes, Ping Liang, Robert A. Gatenby, Mokenge Malafa, Sakhrat Khizroev   +28 more
wiley   +1 more source

Iron Deficiency in Newly Referred Patients With Chronic Renal Failure. [PDF]

Cureus
Kitamura M, Yamashita H, Kuroki R, Fukuda H, Sawase A, Mukae H, Nishino T.   +6 more
europepmc   +1 more source

Integrin β3 Orchestrates Hepatic Steatosis via a Novel CD36‐Dependent Lipid Uptake Complex

Advanced Science, EarlyView.
In MASH, ITGB3 recruits LYN and drives its ubiquitin‐proteasomal degradation via phosphorylation. This relieves DHHC5 inhibition, enabling ITGB3/DHHC5/CD36 complex assembly to enhance CD36 palmitoylation and fatty acid uptake, thereby exacerbating disease. Targeting ITGB3 blocks this pathogenic axis and ameliorates MASH.
Ying Zhang, Lei Dai, Zhongquan Cui, Ye Zhou, Wenyuan Dong, Hongcheng Jiang, Mengwen Wang, Xiaodan Zhong, Wei Dong, Zhang Yue, Thati Madhusudhan, Hongjie Wang, Xiong Zhong Ruan, Hesong Zeng   +13 more
wiley   +1 more source

Endogenous Candida albicans endophthalmitis in a patient with chronic renal failure on hemodialysis. [PDF]

Int J Ophthalmol
Liu MY, Chen ZF, Liu HS, Meng QL.
europepmc   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Determination of HLA Tissue Type According to the Etiology of Patients with Chronic Renal Failure. [PDF]

Medeni Med J
Karakus Turan B, Ucar F, Yilmaz VT, Kilinc Y, Darbaş Aras S, Kocak H, Sayin Ekinci N, Aydinli B, Arslan HS.   +8 more
europepmc   +1 more source

STUDY OF RENAL OSTEODYSTROPHY IN CHRONIC RENAL FAILURE

, 2016
Nalina Thimmappa, Giriraja Kanakapura Vrushabaih, Pula Laxmi Bindumathi, Pooja Pillai, Bhaskar Balasundaram   +4 more
openalex   +1 more source