Results 81 to 90 of about 4,338,055 (298)

An Anti‐Amyloidogenic Approach to Specifically Block Memory Consolidation in Mice for Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
Functional amyloid conversion of the translation regulator CPEB3 is essential for long‐term memory persistence. This study demonstrates that targeting this molecular switch with the anti‐amyloidogenic peptide QBP1 selectively blocks CPEB3 fibrillation without disrupting phase separation.
Paula López‐García   +13 more
wiley   +1 more source

Chronic renal failure in patients hospitalized for heart failure

open access: yesCardiologia Hungarica
Aim of the study: Assessment of the incidence of real and diagnosed chronic renal failure in patients hospitalized for heart failure, assessment of factors affecting the recording of the diagnosis.
Tomcsányi János   +3 more
doaj   +1 more source

Safe spinal anesthesia in a woman with chronic renal failure and placenta previa

open access: yes, 2010
Beyazit ZencirciKahramanmaras, TurkeyBackground: Chronic renal failure is strongly associated with poor pregnancy outcome. Women dependent on hemodialysis before conception rarely achieve a successful live birth.Case presentation: A 31-year-old ...
Beyazit Zencirci
core  

Activation of Rac-1 and RhoA contributes to podocyte injury in chronic kidney disease [PDF]

open access: yes, 2013
Rho-family GTPases like RhoA and Rac-1 are potent regulators of cellular signaling that control gene expression, migration and inflammation. Activation of Rho-GTPases has been linked to podocyte dysfunction, a feature of chronic kidney diseases (CKD). We
Liliana Schäfer   +56 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Dry Eye in Children with Chronic Renal Failure

open access: yesTürk Oftalmoloji Dergisi, 2014
Objectives: To evaluate the dry eye symptoms based on objective test and subjective findings in children with chronic renal failure (CRF) and to compare the results with those in healthy subjects.
Pınar Yüksekkaya   +2 more
doaj   +1 more source

Natriumphosphat enthaltende Darmreinigungsmittel – eine Gefahr für die Niere? [PDF]

open access: yes, 2009
There are several well-documented cases of acute irreversible renal failure involving renal calcium phosphate deposits after the use of bowel preparations containing sodium phosphate (e.g., Colophos®).
Bock, A   +7 more
core   +2 more sources

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang   +11 more
wiley   +1 more source

The relationship between chronic kidney disease and cancer [PDF]

open access: yesJournal of Nephropathology, 2018
Seyed Majid Mousavi Movahhed   +6 more
doaj   +1 more source

Cisplatin Induced Nephrotoxicity

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2014
Cisplatin is a potent chemotherapy agent which is used to treat a broad spectrum of solid cancers. However, its clinical use is limited due to its nephrotoxicity with a decline in the glomerular filtration rate that occur in 15-30% of patients.
Seyed Seifollah Beladi Mousavi   +1 more
doaj  

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