Results 91 to 100 of about 210,758 (351)

High fludarabine exposure and relationship with treatment-related mortality after nonmyeloablative hematopoietic cell transplantation. [PDF]

, 2011
Despite its common use in nonmyeloablative preparative regimens, the pharmacokinetics of fludarabine are poorly characterized in hematopoietic cell transplantation (HCT) recipients and exposure-response relationships remain undefined.
Brunstein, CG, Cao, Q, Green, KG, Jacobson, PA, Long-Boyle, JR, McGlave, PB, Miller, JS, Rogosheske, J, Wagner, JE, Weisdorf, DJ   +9 more
core   +1 more source

Urbanization and non-communicable disease mortality in Thailand: an ecological correlation study.

, 2013
This study provides strong evidence from an LMIC that urbanization is associated with mortality from three lifestyle-associated diseases at an ecological level.
Allender, Allender, Archavanitkul, Banwell, Bentham, Boutayeb, Cochrane, Cohen, Faramnuayphol, Flood, Harpham, Hernandez, Holt-Lunstad, Kosulwat, Leon, Lim, Maheswaran, Mathers, Odton, Pattaraarchachai, Petcharoen, Phillips, Porapakkham, Pritchard, Rao, Schorr, Sethapongkul, Sleigh, Smith, Srimahachota, Tangcharoensatien, Vapattanawong, Venketasubramanian, Viravaidya, Vlahov, World Health Organization, Yang, Yiengprungsawan, Yiengprungsawan, Young   +39 more
core   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

Adrenal Crisis [PDF]

, 2019
Glucocorticoid replacement therapy, available since the 1950s, has prolonged the survival of patients with adrenal insufficiency. However, adrenal crises, which are life-threatening medical emergencies, still develop in many affected patients.
Falhammar, Henrik, Rushworth, R Louise, Torpy, David J   +2 more
core   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Clinicopathological analyses of aged nephrotic syndrome

Linchuang shenzangbing zazhi, 2015
Objective To understand the nephritic syndrome in the elderly.Methods Clinicopathological analyses were performed on 287 patients with nephritic syndrome.According to the pathological WHO 1995 glomerular disease classification standard classification ...
TAO Juan, HAO Li
doaj  

Does oral sodium bicarbonate therapy improve function and quality of life in older patients with chronic kidney disease and low-grade acidosis (the BiCARB trial)? Study protocol for a randomized controlled trial [PDF]

, 2015
Date of acceptance: 01/07/2015 © 2015 Witham et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and ...
A Mahajan, Alison Avenell, AM Kamper, AT Johnston, B Iorio Di, BA Hout van, BT Workeneh, D Reaich, Deepa Sumukadas, Edmund J. Lamb, Geeta Hampson, H Roberts, I Brito-Ashurst, J Coresh, J Coresh, JA Eustace, JA Kraut, JA Kraut, JC Davis, JM Guralnik, JM Guralnik, K Baboolal, K Bibbins-Domingo, L Ceglia, LD Hughes, M Dobre, M Dobre, M Gaggl, Margaret M. Band, Marion E. T. McMurdo, ME McMurdo, ME McMurdo, Miles D. Witham, MR Wiederkehr, P Laukkanen, P Susantitaphong, Paul McNamee, PE Stevens, RB Haynes, RD Hays, Roberta C. Littleford, Roy L. Soiza, Simon A. Ogston, SJ Walters, T Rantanen, V Menon, WN Wennie Huang   +46 more
core   +4 more sources

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

Association between simple renal cyst and kidney damage in a Chinese cohort study

Renal Failure, 2019
Background: The presence of simple renal cyst (SRC) has been associated to renal dysfunction, but the results were inconsistent. Accordingly, we conducted a longitudinal cohort study to explore the association between SRC and kidney damage.
Juan Chen, Xiaojing Ma, Dongmei Xu, Wei Cao, Xianglei Kong   +4 more
doaj   +1 more source

Smart Catheters for Diagnosis, Monitoring, and Therapy

Advanced Healthcare Materials, EarlyView.
This study presents a comprehensive review of smart catheters, an emerging class of medical devices that integrate embedded sensors, robotics, and communication systems, offering increased functionality and complexity to enable real‐time health monitoring, diagnostics, and treatment. Abstract This review explores smart catheters as an emerging class of
Azra Yaprak Tarman, Samiha Ahmed, Majed Othman Althumayri, Megan Guy, Darlenne Chavez Lugo, Frances S. Ligler, George T. Ligler, Rahmi Oklu, Hiroshi Kawahira, Michael J. McShane, Jun Kameoka, Jonathan Bova, Hatice Ceylan Koydemir   +12 more
wiley   +1 more source