Results 131 to 140 of about 394,507 (347)

[Chronic renal insufficiency: 1) adaptation of nephron function in chronic renal insufficiency and 2) progression of chronic renal insufficiency].

Srpski arhiv za celokupno lekarstvo, 1999
In chronic renal insufficiency resulting from destruction of the vast majority of nephrons, the surviving nephrons adapt their functions to the conditions of vigorous haemodynamic and osmolar overloads. They acquire an appropriate behaviour to preserve the principal renal functions and to achieve the balance of inner space.
openaire   +1 more source

Progression of retinopathy and incidence of cardiovascular disease: findings from the Chronic Renal Insufficiency Cohort Study

, 2020
Juan E. Grunwald, Maxwell Pistilli, Gui‐Shuang Ying, Maureen G. Maguire, Ebenezer Daniel, Revell Whittock-Martin, Candace Parker-Ostroff, Douglas Jacoby, Alan S. Go, Raymond R. Townsend, Crystal A. Gadegbeku, James P. Lash, Jeffrey C. Fink, Mahboob Rahman, Harold I. Feldman, John W. Kusek, Dawei Xie   +16 more
openalex   +2 more sources

Biomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.
Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji   +17 more
wiley   +1 more source

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Retracted: Clinical Effect of Mudan Granule on Peripheral Neuritis Caused by Chronic Renal Insufficiency. [PDF]

Comput Math Methods Med, 2023
Methods In Medicine CAM.
europepmc   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

Advanced Science, EarlyView.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang, Min‐Yu Tsou, Pin‐Hung Li, Jo‐Ching Chen, Yen‐Liang Liu, Gideon Meyerowitz‐Katz, Tsung‐Hsun Tsai, Pen‐Hua Su   +7 more
wiley   +1 more source

Fibroblast Growth Factor 23 and Anemia in the Chronic Renal Insufficiency Cohort Study.

American Society of Nephrology. Clinical Journal, 2017
Rupal Mehta, Xuan Cai, Alexander J. Hodakowski, J. Lee, M. Leonard, A. Ricardo, J. Chen, L. Hamm, J. Sondheimer, M. Dobre, V. David, Wei Yang, A. Go, J. Kusek, H. Feldman, M. Wolf, T. Isakova   +16 more
semanticscholar   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

CT pulmonary angiography in patients with acute or chronic renal insufficiency: Evaluation of a low dose contrast material protocol [PDF]

, 2018
Mathias Meyer, Holger Haubenreisser, Christoph Schabel, Christianne Leidecker, Bernhard Schmidt, Stefan O. Schoenberg, Thomas Henzler   +6 more
openalex   +1 more source

Genome-Wide Association of CKD Progression: The Chronic Renal Insufficiency Cohort Study.

Journal of the American Society of Nephrology, 2017
A. Parsa, P. Kanetsky, Rui Xiao, J. Gupta, N. Mitra, Sophie Limou, D. Xie, Huichun Xu, A. Anderson, A. Ojo, J. Kusek, C. Lora, L. Hamm, Jiang He, N. Sandholm, Janina M. Jeff, Dominic E. Raj, Carsten A. Böger, E. Bottinger, S. Salimi, R. Parekh, Sharon Adler, C. Langefeld, D. Bowden, P. Groop, C. Forsblom, B. Freedman, M. Lipkowitz, Caroline S. Fox, C. Winkler, Harold I. Feldman   +30 more
semanticscholar   +1 more source