Results 161 to 170 of about 118,394 (314)

Novel erythropoiesis stimulating protein for treatment of anemia in chronic renal insufficiency [PDF]

, 2001
Francesco Locatelli, J. Olivares, Rowan G. Walker, Martin Wilkie, B S Jenkins, Claire Dewey, Stephen J. Gray   +6 more
openalex   +1 more source

Predicting Maternal and Fetal Exposures of Elexacaftor–Tezacaftor–Ivacaftor during Pregnancy through Physiologically Based Pharmacokinetic Models

Clinical Pharmacology &Therapeutics, EarlyView.
The use of elexacaftor/tezacaftor/ivacaftor (ETI) has been associated with increased fertility in women with cystic fibrosis (CF) and is increasingly used during pregnancy to support both maternal and fetal health. However, little is known about the pharmacokinetics (PK) of ETI during pregnancy, which is crucial for optimizing its efficacy and safety ...
Eunjin Hong, Mary F. Hebert, Emily Fay, Grant Turner, Patricia Eshaghian, Aaron Trimble, Peter S. Chung, Adupa P. Rao, Paul M. Beringer   +8 more
wiley   +1 more source

Deoxycholic Acid and Coronary Artery Calcification in the Chronic Renal Insufficiency Cohort. [PDF]

J Am Heart Assoc, 2022
Jovanovich A, Cai X, Frazier R, Bundy JD, He J, Rao P, Lora C, Dobre M, Go A, Shafi T, Feldman HI, Rhee EP, Miyazaki M, Isakova T, Chonchol M, CRIC Study Investigators [Link].   +15 more
europepmc   +1 more source

Plasma Levels of 5-Hydroxyindole-Acetic Acid in Chronic Renal Insufficiency and Their Effect on Platelet Aggregation

, 1991
Katarı́na Šebeková, K Opatrný, R Dzúrik   +2 more
openalex   +1 more source

Population Pharmacokinetic/Toxicodynamic Model for Polymyxin B in Critically Ill Patients to Identify the Risk of Nephrotoxicity

Clinical Pharmacology &Therapeutics, EarlyView.
Polymyxins are used against highly resistant Gram‐negative pathogens, and nephrotoxicity (acute kidney injury, AKI) is the major dose‐limiting adverse effect. We aimed to develop a well‐informed population pharmacokinetic/toxicodynamic (PK/TD) model using the largest polymyxin B‐treated critically ill patient population studied to inform polymyxin B ...
Patrick O. Hanafin, Ramya Mahadevan, Gauri G. Rao, Alexandre P. Zavascki, Ana Maria Sandri, Andrea Kwa, Marc H. Scheetz, Christine J. Kubin, Jayesh Shah, Benjamin P.Z. Cherng, Michael T. Yin, Jiping Wang, Lu Wang, David P. Calfee, Maureen Bolon, Anthony W. Purcell, Roger L. Nation, Jason M. Pogue, Jian Li, Keith S. Kaye   +19 more
wiley   +1 more source

Association of Vitamin K Status with Arterial Calcification and Stiffness in Chronic Kidney Disease: The Chronic Renal Insufficiency Cohort. [PDF]

Curr Dev Nutr, 2023
Shea MK, Wang J, Barger K, Weiner DE, Townsend RR, Feldman HI, Rosas SE, Chen J, He J, Flack J, Jaar BG, Kansal M, Booth SL, CRIC Study Investigators.   +13 more
europepmc   +1 more source

Improved Growth in Young Children with Severe Chronic Renal Insufficiency Who Use Specified Nutritional Therapy [PDF]

, 2001
Rulan S. Parekh, Joseph T. Flynn, William E. Smoyer, Joan L. Milne, David B. Kershaw, Timothy E. Bunchman, Aileen B. Sedman   +6 more
openalex   +1 more source

Progress in Pharmacogenomics Implementation in the United States: Barrier Erosion and Remaining Challenges

Clinical Pharmacology &Therapeutics, EarlyView.
Barriers to incorporating pharmacogenetics into routine clinical practice in the United States are well documented. Initial surveys by the Clinical Pharmacogenetics Implementation Consortium (CPIC) in 2009 and 2010 identified barriers across four key domains that have hindered the widespread adoption of clinical pharmacogenetic testing.
D. Max Smith, Michael P. Douglas, Christina L. Aquilante, Patricia A. Deverka, Beth Devine, Henry M. Dunnenberger, Philip E. Empey, Daniel L. Hertz, Andrew A. Monte, Ann M. Moyer, Jai N. Patel, Victoria M. Pratt, Loren Saulsberry, Stuart A. Scott, Deepak Voora, Erica L. Woodahl, Michelle Whirl‐Carrillo, Akinyemi Oni‐Orisan, on behalf of the Pharmacogenomics Global Research Network (PGRN) Publications Committee   +18 more
wiley   +1 more source

Heart Failure-Type Symptom Score Trajectories in CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. [PDF]

Am J Kidney Dis, 2023
Walther CP, Benoit JS, Bansal N, Nambi V, Navaneethan SD, CRIC Study Investigators.   +5 more
europepmc   +1 more source

Avoiding infrainguinal bypass wound complications in patients with chronic renal insufficiency: The role of the anatomic plane

, 1996
Jan D. Blankensteijn, Jonathan P. Gertler, Michael J. Petersen, D C Brewster, Richard P. Cambria, Glenn M. LaMuraglia, William M. Abbott   +6 more
openalex   +1 more source