Results 61 to 70 of about 118,394 (314)

Can an Ad-hoc ontology Beat a Medical Search Engine? The Chronious Search Engine case [PDF]

arXiv, 2012
Chronious is an Open, Ubiquitous and Adaptive Chronic Disease Management Platform for Chronic Obstructive Pulmonary Disease(COPD) Chronic Kidney Disease (CKD) and Renal Insufficiency. It consists of several modules: an ontology based literature search engine, a rule based decision support system, remote sensors interacting with lifestyle interfaces ...
arxiv  

Intrinsically Soft Implantable Electronics for Long‐term Biosensing Applications

Advanced Sensor Research, EarlyView.
Intrinsically soft implantable biosensors address the mechanical mismatch of conventional rigid implants, improving biocompatibility and stability. This review explores soft encapsulation matrices, stretchable conductors, implantation strategies, and chronic fixation techniques.
Su Hyeon Lee, Hyo Jin Lee, Sohye Lee, Dae‐Hyeong Kim, Hye Jin Kim, Sung‐Hyuk Sunwoo   +5 more
wiley   +1 more source

Tuneled catheters in femoral vein: does the length makes any difference?

Revista Colombiana de Nefrología, 2018
Objective: To establish if 23 cm length, tunneled catheters, are associated to better outcomes than 19 cm ones. Patients, Materials and Methods: Patients with CKD G5D, which the only vascular access alternative was the femoral vein.
César Augusto Restrepo Valencia, José Vicente Aguirre Arango, Carlos Alberto Buitrago Villa   +2 more
doaj   +1 more source

An Empirical Biomarker-based Calculator for Autosomal Recessive Polycystic Kidney Disease - The Nieto-Narayan Formula [PDF]

, 2016
Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts. The disease is congenital and children that do not succumb to it during the neonatal period will, by age 10 years, more often than not, require nephrectomy+renal replacement therapy for ...
arxiv   +1 more source

Renal handling of potassium in dogs with chronic renal insufficiency

Kidney International, 1981
The dynamics of potassium excretion were examined in normal dogs and dogs with chronic renal insufficiency of at least 4 weeks' duration (remnant model). All animals, in balance on diets providing 15, 50, or 100 mEq of potassium and 100 mEq of sodium, were challenged with 50 mEq of potassium chloride.
Jillian Pincus, George Gavellas, Michael A. Kaplan, Jacques J. Bourgoignie, Alexander Rabinovitch   +4 more
openaire   +3 more sources

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

Renal Parenchymal Area and Kidney Collagen Content [PDF]

arXiv, 2016
The extent of renal scarring in chronic kidney disease (CKD) can only be ascertained by highly invasive, painful and sometimes risky tissue biopsy. Interestingly, CKD-related abnormalities in kidney size can often be visualized using ultrasound. Nevertheless, not only does the ellipsoid formula used today underestimate true renal size but also the ...
arxiv  

Efficient and Specific PDGFRβ‐Targeting Dual‐Mode T1‐T2 MRI Nanoprobe for Early Diagnosis of Non‐Alcoholic Fatty Liver

Advanced Science, EarlyView.
The Fe3O4/Gd@BSA‐pPB nanoprobe leverages biomimetic mineralization and targets hepatic stellate cells (HSCs) through PDGFRβ, offering superior enrichment in fibrotic regions. This targeted delivery overcomes biological barriers, enhancing both the accuracy and sensitivity of MRI imaging at early disease stages.
Zehua Li, Tongwei Zhang, Tongxiang Tao, Yaxuan Liu, Haining Xia, Sajid ur Rehman, Zeyong Guo, Jing Zhang, Ruiguo Chen, Zhan Zhang, Junfeng Wang, Kun Ma   +11 more
wiley   +1 more source

Pyruvate Carboxylase in Macrophages Aggravates Atherosclerosis by Regulating Metabolism Reprogramming to Promote Inflammatory Responses Through the Hypoxia‐Inducible Factor‐1 Signaling Pathway

Advanced Science, EarlyView.
This study investigates the role of macrophage pyruvate carboxylase (PC) in atherosclerosis (AS) demonstrating that PC upregulation in macrophages promotes metabolism reprogramming to enhance inflammatory responses via the HIF‐1 signaling pathway.
Ling‐Na Zhao, Rui‐Ling Wang, Ran‐Xin Liu, Meng‐Ru Zheng, Li Zhao, Bao‐Feng Li, Jia‐Le Li, De‐Shen Liu, Xiao‐Xia He, Qin‐Bao Peng, Kai Li, Tian‐Xiao Lin, Ying‐Ying Liu, Sheng‐Ping He, Jun Lu, Shao‐Yi Zheng, Xiu Liu, Fang‐Ze Huang   +17 more
wiley   +1 more source

Arterial stiffening provides sufficient explanation for primary hypertension [PDF]

, 2013
Hypertension is one of the most common age-related chronic diseases and by predisposing individuals for heart failure, stroke and kidney disease, it is a major source of morbidity and mortality. Its etiology remains enigmatic despite intense research efforts over many decades.
arxiv   +1 more source