Results 61 to 70 of about 620,869 (306)

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension [PDF]

, 2013
In the spontaneously hypertensive (SH) rat, hyperoxic inactivation of the carotid body (CB) produces a rapid and pronounced fall in both arterial pressure and renal sympathetic nerve activity (RSA).
Abdala, Ana P, Hendy, Emma B, Marvar, Paul, McBryde, Fiona D, Moraes, Davi J A, Paton, Julian F R, Pijacka, Wioletta, Sobotka, Paul A   +7 more
core   +2 more sources

Highlights from the Respiratory Failure and Mechanical Ventilation 2020 Conference

ERJ Open Research, 2021
The Respiratory Intensive Care Assembly of the European Respiratory Society organised the first Respiratory Failure and Mechanical Ventilation Conference in Berlin in February 2020.
Adelaide Withers, Tiffany Choi Ching Man, Rebecca D'Cruz, Heder de Vries, Christoph Fisser, Carla Ribeiro, Neeraj Shah, Marine Van Hollebecke, Bettine A.H. Vosse, Leo Heunks, Maxime Patout   +10 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

P/F Ratio is a Better Predictor for Non-Invasive Ventilation Failure and Length of Stay in Patients with Community-Acquired Pneumonia

Jurnal Respirasi
Introduction: Community-acquired pneumonia (CAP) can deteriorate into respiratory failure requiring immediate ventilatory intervention. This study compared the performance of the PaO2/FiO2 (P/F) ratio, the ratio of oxygen saturation (ROX) index, and the ...
Brigitta Anindita Devi Hapsari, Olivia Geraldine Roxanne, Reviono Reviono, Artrien Adhiputri, Hendrastutik Apriningsih, Nur Indah Rahayu, Guido Vagheggini   +6 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Direct admission to the intensive care unit from the emergency department and mortality in critically ill hematology patients [PDF]

, 2019
Background: The aim of this study was to assess the benefit of direct ICU admission from the emergency department (ED) compared to admission from wards, in patients with hematological malignancies requiring critical care.
Azoulay, Elie, Benoit, Dominique, Bruneel, Fabrice, Chevret, Sylvie, Demoule, Alexandre, Kouatchet, Achille, Lebert, Christine, Lemiale, Virginie, Meert, Anne-Pascale, Mirouse, Adrien, Mokart, Djamel, Nyunga, Martine, Perez, Pierre, Peyrony, Olivier, Pène, Frédéric   +14 more
core   +2 more sources

A case of lateral medullary infarction with severe dysphagia and worsening of respiratory failure in the chronic phase of recovery

Clinical Case Reports, 2018
Key Clinical Message Patients with lateral medullary infarction (LMI) sometimes present with respiratory failure in the acute or subacute phase. We experienced a LMI patient with progression of respiratory failure that required bilevel positive airway ...
Yusuke Mon, Chisato Tamaki
doaj   +1 more source

Survey on accessibility and real-life application of noninvasive ventilation

ERJ Open Research, 2018
Noninvasive mechanical ventilation (NIV) is an accepted method of respiratory failure treatment; however, at present, little is known about the global factors limiting NIV application. A survey designed to determine NIV accessibility and limiting factors
Szymon Skoczyński, Raffaele Scala, Paolo Navalesi   +2 more
doaj   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]

, 2013
[no ...
Abdala, Ana P, Burchell, Amy, Engleman, Zoar J, Fudim, Marat, Gourine, Alexander V, Hart, Emma C J, Lobo, Mel, Marina, Nepthali, McBryde, Fiona D, Nightingale, Angus, Patel, Nik, Paton, Julian F R, Ratcliffe, Laura E K, Sobotka, Paul A   +13 more
core   +2 more sources