Results 161 to 170 of about 4,487,488 (290)

NONINVASIVE VENTILATORY SUPPORT ON CHRONIC RESPIRATORY FAILURE WITH HYPOVENTILATION.

open access: yes, 1989
Chest negative pressure ventilation (CNPV) and intermittent positive pressure ventilation (IPPV) through a nose mask were used for ventilatory support of 4 patients with chronic respiratory failure due to old tuberculosis (2 patients), chronic pulmonary ...
大井, 元晴   +2 more
core  

A Dual‐Membrane Biomimetic Nanoplatform Enables Triple‐Modal Therapy Against SARS‐CoV‐2 Through Viral Decoy, Inflammation Neutralizing, and Intracellular RNAi

open access: yesAdvanced Science, EarlyView.
[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li   +19 more
wiley   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

open access: yesAdvanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen   +17 more
wiley   +1 more source

Respiratory failure

open access: yes
Acute respiratory failure encompasses both hypoxaemic (type 1) and hypercapnic (type 2) patterns, each arising from distinct pathophysiological mechanisms and clinical contexts. Type 1 respiratory failure is defined by a low PaO₂ with normal or low PaCO₂.

core   +1 more source

Restoring Endothelial Mitochondrial Homeostasis With a Bioactive Nanoshield Promotes Vascular Regeneration on Cardiovascular Implants

open access: yesAdvanced Science, EarlyView.
A bioactive poly(citrate‐polyglycol‐procyanidin) (PCGP) nanoshield is developed for cardiovascular implants to restore endothelial mitochondrial homeostasis following vascular injury. By preserving mitochondrial integrity, re‐establishing metabolic balance, and activating PI3K/Akt/eNOS‐NO signaling, the PCGP interface promotes functional endothelial ...
Xiyu Liu   +14 more
wiley   +1 more source

Lung function decline preceding chronic respiratory failure in spinal muscular atrophy: a national prospective cohort study. [PDF]

open access: yesOrphanet J Rare Dis, 2023
Veldhoen ES   +16 more
europepmc   +1 more source

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