Objectives. The BODE (BMI, Obstruction - FEV1, Dyspnoea - mMRC, Exercise - 6-MWT) and the ADO (Age, Dyspnoea - mMRC, Obstruction - FEV1) indices are widely used prognosis assessment tools for long-term mortality prediction in COPD patients but subject to
Kristian Brat +12 more
doaj +1 more source
Respiratory muscle dysfunction in acute and chronic respiratory failure: how to diagnose and how to treat? [PDF]
Assessing and treating respiratory muscle dysfunction is crucial for patients with both acute and chronic respiratory failure. Respiratory muscle dysfunction can contribute to the onset of respiratory failure and may also worsen due to interventions ...
Poddighe D +9 more
europepmc +2 more sources
Airway bacterial and fungal microbiome in chronic obstructive pulmonary disease
Little is known about airway mycobiome, and its relationship with bacterial microbiome in chronic obstructive pulmonary disease (COPD). Here we report the first simultaneous characterization of sputum bacterial and fungal microbiome in 84 stable COPD and
Haiyue Liu +14 more
doaj +1 more source
The Interactions of Airway Bacterial and Fungal Communities in Clinically Stable Asthma
Dysbiotic airway microbiota play important roles in the inflammatory progression of asthma, and exploration of airway microbial interactions further elucidates asthma pathogenesis.
Hai-yue Liu +10 more
doaj +1 more source
Global and regional burden of chronic respiratory disease in 2016 arising from non-infectious airborne occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016 [PDF]
OBJECTIVES: This paper presents detailed analysis of the global and regional burden of chronic respiratory disease arising from occupational airborne exposures, as estimated in the Global Burden of Disease 2016 study.
GBD 2016 Occupational Chronic Respiratory Risk Factors Collaborators +3 more
core +1 more source
OBJECTIVES:. Hyper- and hypoinflammatory subphenotypes discovered in patients with acute respiratory distress syndrome predict clinical outcomes and therapeutic responses. These subphenotypes may be important in broader critically ill patient populations
Callie M. Drohan, MD +8 more
doaj +1 more source
Chronic obstructive pulmonary disease and respiratory failure
Chronic obstructive pulmonary disease is a current problem for elderly patients due to diffusion, mortality, and other negative outcomes. The most complex management aspects consist of the presence of frailty, which increases the risk of complications ...
Giulia Mussatti +6 more
doaj +1 more source
Personalised pulmonary rehabilitation in COPD
This review summarises ongoing developments in personalised medicine and individualised medicine in chronic obstructive pulmonary disease (COPD). Currently applied classification systems largely ignore the complexity and heterogeneity of the COPD ...
Emiel F.M. Wouters +5 more
doaj +1 more source
Predictive significance of the six-minute walk distance for long-term survival in chronic hypercapnic respiratory failure [PDF]
Background: The 6-min walk distance ( 6-MWD) is a global marker of functional capacity and prognosis in chronic obstructive pulmonary disease ( COPD), but less explored in other chronic respiratory diseases.
Arzt, Michael +8 more
core +1 more source
Real-world practice of idiopathic pulmonary fibrosis: Results from a 2000–2016 cohort
The study aimed to investigate comorbidities, major adverse respiratory events, and mortality in patients with idiopathic pulmonary fibrosis (IPF). We established an IPF cohort and a comparative cohort matched for sex, age, and the date of IPF diagnosis.
Wang Ying-Tso +5 more
doaj +1 more source

