Results 111 to 120 of about 2,678,121 (354)

Chronic rhinosinusitis and neuropeptides

Swiss Medical Weekly, 2003
The nose is an air conditioner and is involved in the protection of the lower airways against inhalation of exogenous particles and airborne irritants. The nasal mucosa is therefore densely innervated by sensory nerves containing several neuropeptides. In the airways, activation of sensory C and A? fibres leads to the release of multiple neuropeptides.
openaire   +3 more sources

Alveolar Extracellular Vesicles May Protect Some Patients With Chronic Aspiration From Pneumonia

The Laryngoscope, EarlyView.
A subset of patients with chronic aspiration appear to be relatively protected against pneumonias. This prospective observational study examines the alveolar fluid of patients with chronic aspiration with and without pneumonia. We found relatively little difference in classical cytokine levels but a difference in both the level and protein composition ...
James T. Ross, Nina W. Zhao, Dino Petrov, Ching‐Wen Lin, Alyssa Bellini, Neona Lowe, Bryan Nguyen, Dustin Hadley, Randy P. Carney, Anamaria J. Robles, Rachael A. Callcut, Peter C. Belafsky   +11 more
wiley   +1 more source

The Global Allergy and Asthma European Network (GALEN rhinosinusitis cohort: a large European cross-sectional study of chronic rhinosinusitis patients with and without nasal polyps.

Rhinology, 2019
BACKGROUND Chronic rhinosinusitis (CRS) is a common yet under-recognised chronic inflammatory disease of the nose and paranasal sinuses that is classified according to the presence (CRSwNP) or absence (CRSsNP) of nasal polyps.
Asif H Khan, G. Vandeplas, T. Huynh, Vijay N. Joish, L. Mannent, P. Tomassen, T. Zele, L. Cardell, Julia Arebro, H. Olze, U. Foerster-Ruhrmann, M. L. Kowalski, A. Olszewska-Ziąber, G. Holtappels, N. D. Ruyck, C. V. Drunen, J. Mullol, P. Hellings, V. Hox, E. Toskala, G. Scadding, V. Lund, W. Fokkens, Claus Bachert   +23 more
semanticscholar   +1 more source

Effectiveness and Safety of Dupilumab Monotherapy in Japanese Patients With Chronic Rhinosinusitis With Nasal Polyps

The Laryngoscope, EarlyView.
In this phase 4, open‐label, single‐arm, multicenter study, dupilumab monotherapy was associated with reductions from baseline to week 24 (primary endpoint) in the bilateral endoscopic Nasal Polyp Score (NPS) in 25 Japanese adults with inadequately controlled chronic rhinosinusitis with nasal polyps on standard care therapies.
Shigeharu Fujieda, Tetsuji Takabayashi, Nobuo Ohta, Mamoru Yoshikawa, Yuki Kibe, Masato Ishida, Katsuhisa Suzuki, Yoshinori Takahashi, Nikhil Amin, Lakiea Wright, Lacey Robinson, Kenji Yahata   +11 more
wiley   +1 more source

Bronchiectasis and chronic rhinosinusitis

Respiratory Medicine CME, 2008
SummaryA patient with post-traumatic rhinosinusitis for 10 years developed recurrent chest infections. Computed tomographic scanning demonstrated diffuse bronchiectasis. The bronchiectasis appeared to have developed as a complication of persistent upper airway sepsis.
openaire   +2 more sources

Long‐Term Cost Utility Analysis of Endoscopic Sinus Surgery: Analysis of 5‐Year Outcomes

The Laryngoscope, EarlyView.
This study utilizes a cohort‐style Markov decision tree economic model to evaluate the long‐term (5‐year) cost‐effectiveness of endoscopic sinus surgery versus medical management for patients with chronic rhinosinusitis. The results show that the endoscopic sinus surgery strategy cost more ($63,296.27) but yielded increased quality‐adjusted life years (
Dara R. Adams, Katherine Tashman, Eric H. Holbrook, Stacey T. Gray, Ralph Metson, George Scangas   +5 more
wiley   +1 more source

Chronic sphenoid rhinosinusitis: management challenge

Journal of Asthma and Allergy, 2016
Natamon Charakorn, Kornkiat Snidvongs Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand Abstract: Chronic sphenoid rhinosinusitis is a ...
Charakorn N, Snidvongs K
doaj  

Angiotensin-Converting Enzyme Insertion/Deletion Gene Polymorphism in Chronic Rhinosinusitis with Nasal Polyps

Turkish Archives of Otorhinolaryngology
Objective: Inflammatory processes play a role in the etiopathogenesis of chronic rhinosinusitis. Many gene polymorphisms have been associated with inflammation.
Mehmet Emre Sivrice, Vural Akın, Hasan Yasan, Kuyaş Hekimler Öztürk, Yusuf Çağdaş Kumbul   +4 more
doaj   +1 more source

Impact of Obesity on the Structured Histopathology of Chronic Rhinosinusitis Patients

The Laryngoscope, EarlyView.
ABSTRACT Objectives Obesity is an established risk factor for asthma, which shares common inflammatory pathways with chronic rhinosinusitis (CRS). However, the link between obesity and CRS remains poorly understood. By identifying trends in the structured histopathology (SHP) of obese patients with CRS, we aim to better understand how changes in the ...
Daniel X. Ma, Sushanth Neerumalla, Ali Baird, Russell A. Whitehead, Peter Filip, Bobby A. Tajudeen, Pete S. Batra, Peter Papagiannopoulos   +7 more
wiley   +1 more source

Polyphenolic Activation of Basophils Explains Alcohol Hypersensitivity in AERD

The Laryngoscope, EarlyView.
The mechanism behind alcohol sensitivity in AERD has not been previously characterized. This study demonstrates the activation of basophils in patients with CRSwNP and AERD by polyphenolic compounds, but not ethanol. Since these compounds can be found in alcoholic beverages in similar frequencies by which they trigger symptoms, this research provides a
Spencer C. Payne, William Eschenbacher, Ryan Stepp, Larry Borish   +3 more
wiley   +1 more source