Results 171 to 180 of about 2,745,887 (383)

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Clinical Utility of Machine Learning Methods Using Regression Models for Diagnosing Eosinophilic Chronic Rhinosinusitis

OTO Open
Objective Machine learning methods using regression models can predict actual values of histological eosinophil count from blood eosinophil levels. Therefore, these methods might be useful for diagnosing eosinophilic chronic rhinosinusitis, but their ...
Hiroatsu Hatsukawa, Masaaki Ishikawa
doaj   +1 more source

An Endoscopic Study on the Prevalence of Accessory Maxillary Sinus Ostium in Patients with Chronic Rhinosinusitis in Dar es Salaam, Tanzania

Open Access Surgery, 2020
Zephania Saitabau Abraham,1 Aveline Aloyce Kahinga,2 Kassim Babu Mapondella,2 Enica Richard Massawe,2 Daudi Ntunaguzi2 1Department of Surgery, University of Dodoma, College of Health and Allied Sciences, Dodoma, Tanzania; 2Department of ...
Abraham ZS, Kahinga AA, Mapondella KB, Massawe ER, Ntunaguzi D   +4 more
doaj  

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Polymorphisms in the MET/HGF Gene Complex are Associated with Severe Chronic Rhinosinusitis [PDF]

, 2009
Raimundo Castaño Calle, Léandra Mfuna Endam, Abdelali Filali Mouhim, Yohan Bossé, Martin Desrosiers   +4 more
openalex   +1 more source

Sex Hormones and the Risk of Nasal Polyps: A Two‐Sample Mendelian Randomization Study

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The pathophysiological roles of sex hormones in airway inflammation have drawn much attention recently. We aimed to explore the causal effect of sex hormones on chronic rhinosinusitis (CRS) and nasal polyps (NP) via a Mendelian randomization (MR) study.
Ying Zhu, Jia‐Yao Zhou, Shi‐Yao Zhang, Ru Tang, Chun‐Yu Luo, Yue‐Long Gu, Zhi‐Peng Li, Wei‐Tian Zhang   +7 more
wiley   +1 more source

A Delphi Consensus on Clinical Features, Diagnosis, and Treatment of Chronic Rhinosinusitis With Nasal Polyps in the ASEAN Region

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) impacts patients' concentration, ability to work, and overall quality of life. Current treatment options include topical and oral medications, and surgery. Recent evidence supports the efficacy of biologics in improving symptoms and quality of life.
Baharudin Abdullah, Revadi Govindaraju, Salina Husain, Jin Keat Siow, Pongsakorn Tantilipikorn, Neville Wei Yang Teo, De Yun Wang, Deasi Anggraini, Tze Choong Charn, Chao‐Wu David Chin, Dichapong Kanjanawasee, Maung Maung Khaing, Jern‐Lin Leong, Luan Viet Tran, Harvinder Singh, Ing Ping Tang, Kim Thye Mark Thong, Gil M. Vicente, Yoke Yeow Yap, Soma Subramaniam   +19 more
wiley   +1 more source

Treatment & Management of Acute Sinusitis in the Primary Care Setting [PDF]

, 2018
Sinusitis is a leading cause of primary care visits. The majority of cases are due to a viral infection, which can be self-treated with supportive care.
Trieu, Vanessa
core   +1 more source

Interleukin-17A expression in patients with chronic rhinosinusitis and its relationship with clinical features

, 2013
Xi-Dong Hu, Yang‐Yang Bao, Shui‐Hong Zhou, Hong‐Tian Yao, Jianying Mao, Xue‐Xian Ji, Xiaohong Wu   +6 more
openalex   +1 more source

Erythromycin Shortage in an NTM‐Endemic Country: Implications for Bronchiectasis Care and Antimicrobial Stewardship

Respirology, EarlyView.
Takanori Asakura, Ho Namkoong
wiley   +1 more source