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Pathogenesis of Chronic Rhinosinusitis

Annals of Otology, Rhinology & Laryngology, 2004
Chronic rhinosinusitis (CRS) is a multifactorial disease. Predisposing factors can be divided into environmental and non-host factors, such as pollution, viral infections, smoking, fungus, and bacteria; general host factors, including genetic factors and immune deficiency; and local host factors, including persistent focal inflammation within the ...
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Osteitis in Chronic Rhinosinusitis

Current Allergy and Asthma Reports, 2019
Osteitis is recognized as a common factor in recalcitrant chronic rhinosinusitis (CRS). There is evidence for the association of osteitis with revision surgeries and CRS severity, in terms of higher Lund-Mackay scores. This is a narrative review on the osteitis in CRS patients.Evidence to date is inconclusive with regard to the etiology and ...
Kornkiat, Snidvongs   +2 more
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Chronic Rhinosinusitis in Children

Pediatric Clinics of North America, 2013
Chronic rhinosinusitis (CRS) affects nearly 37 million people in the United States each year and accounts for approximately $6 billion in direct and indirect health care costs. Despite its prevalence and significant impact, little is known about its exact cause and pathophysiology, and significant controversy remains regarding appropriate treatment ...
Austin S, Rose   +3 more
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Phototherapy for chronic rhinosinusitis

Lasers in Surgery and Medicine, 2011
Abstract Objectives Near‐infrared laser illumination (NILI), with or without photo‐activated (PA) agents, has bactericidal and wound healing promoting effects. NILI may have a potential role managing chronic rhinosinusitis (CRS). Methods
Yosef P, Krespi, Victor, Kizhner
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Microbiology of chronic rhinosinusitis

European Journal of Clinical Microbiology & Infectious Diseases, 2016
Most sinus infections are viral and only a small percentage develop bacterial infection. Rhino-, influenza, and para-influenza viruses are the most frequent viral causes of sinusitis. The most common bacterial isolates from children and adult patients with community-acquired acute bacterial sinusitis are Streptococcus pneumoniae, Haemophilus influenzae,
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Pathogenesis of chronic rhinosinusitis

Current Allergy and Asthma Reports, 2006
Chronic rhinosinusitis (CRS) is a heterogenous disorder and represents a major public health problem. Although insights into the pathophysiology of CRS have largely expanded over the last two decades, the exact etiology and mechanism of persistence is still unrevealed.
Paul, Van Cauwenberge   +2 more
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Chronic Rhinosinusitis and Asthma

Otolaryngologic Clinics of North America, 2008
Based on considerations of the underlying epidemiology, pathophysiology, histopathology, clinical relationships and treatment outcomes, the links between rhinosinusitis and asthma become evident supporting the unified airway concept.
Stephanie A, Joe, Kunal, Thakkar
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Pediatric chronic rhinosinusitis

Current Opinion in Otolaryngology & Head & Neck Surgery, 2006
Pediatric acute and chronic rhinosinusitis are common pediatric ailments averaging six to eight occurrences a year with 0.5-5% of these progressing to acute sinusitis. A yet undefined number of children progress to chronic sinusitis. Significant resources are spent treating children for sinus infections that would otherwise clear on their own. Practice
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Chronic rhinosinusitis in Asia

Journal of Allergy and Clinical Immunology, 2017
Chronic rhinosinusitis (CRS), although possibly overdiagnosed, is associated with a high burden of disease and is often difficult to treat in those truly affected. Recent research has demonstrated that inflammatory signatures of CRS vary around the world, with less eosinophilic and more neutrophilic inflammation found in Asia compared with Europe and ...
Yuan, Zhang   +6 more
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Management of chronic rhinosinusitis

BMJ, 2012
#### Summary points Chronic rhinosinusitis (CRS) is a common medical condition presenting to the primary care physician. The 2012 update of the European Position Paper on Rhinosinusitis and Nasal Polyps (EP3OS) reported that it may affect between 5% and 15% of the population in Europe and the United States, although high quality epidemiological data ...
K. L. Ah-See   +3 more
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