Results 291 to 300 of about 2,745,887 (383)

Considerations of clinical trial design to evaluate intranasal corticosteroids in patients with chronic rhinosinusitis [PDF]

Brian J. Lipworth, Kirsten Stewart, Chris RuiWen Kuo, Rory Chan   +3 more
openalex   +1 more source

Dynamic Regulation of Collagens, Proteases, Their Inhibitors, and Cell Death in Experimental Asthma in Mice

Allergy, Volume 81, Issue 1, Page 170-184, January 2026.
This study investigates airway remodeling in acute and chronic experimental asthma models induced by house dust mite extract to elucidate inflammatory and structural changes. Two acute T2‐low models demonstrated pronounced airway inflammation characterized by goblet cell hyperplasia, collagen deposition, and significant upregulation of extracellular ...
Marlena Tynecka, Agnieszka Tarasik, Bartosz Hanczaruk, Adrian Janucik, Krystian Czolpinski, Alicja Walewska, Arkadiusz Zbikowski, Anna Zeller, Agnieszka Kulczynska‐Przybik, Magdalena Niemira, Joanna Reszec‐Gielazyn, Barbara Mroczko, Adam Kretowski, Cezmi A. Akdis, Milena Sokolowska, Marcin Moniuszko, Cagatay Karaaslan, Andrzej Eljaszewicz   +17 more
wiley   +1 more source

S100A4 Induces Neutrophilic Inflammation in Chronic Rhinosinusitis with Nasal Polyps via TLR4 Pathway. [PDF]

J Clin Immunol
Tu Y, Li C, Li T, Liu J, Meng L, Liu S, Li P, Wan Y, Chen A, Shi L, Wang DY.   +10 more
europepmc   +1 more source

Clinical efficacy and mechanism-of-action of recombinant IFNα-2b, and IFNα-2b in combination with γ-D-glutamyl-L-tryptophan, in chronic polypous rhinosinusitis with comorbid bronchial asthma

Е. В. Безрукова, E. A. Varyushina, М. А. Афлитонов, S. A. Artyushkin, А. С. Симбирцев   +4 more
openalex   +2 more sources

Defining the Role and Clinical Relevance of Periostin in Chronic Rhinosinusitis with or without Nasal Polyps: a Systematic Review and Meta-analysis. [PDF]

Curr Allergy Asthma Rep
Abdullah B, Mohamad S, Kamarudin IK, Din TADAT, Abdullah NA, Rahman WFWA, Mohmud R.   +6 more
europepmc   +1 more source

Prevalence and Associated Factors of Olfactory and Gustatory Loss in Patients With Nasal Septal Deviation

Clinical Otolaryngology, Volume 51, Issue 1, Page 101-110, January 2026.
ABSTRACT Objectives This study aimed to evaluate the olfactory and gustatory functions of patients with nasal septal deviation (NSD) and identify the factors associated with olfactory loss (OL) and gustatory loss (GL). Design and Setting Retrospective data analysis of cohort group. Participants Two‐hundred fourteen adult patients with NSD at a tertiary
Ja‐Yoon Kim, Hyung‐Ju Cho, Chang‐Hoon Kim, Min‐Seok Rha   +3 more
wiley   +1 more source

Primary Antibody Deficiency in Patients With Chronic Rhinosinusitis: A Call for Immunologic Evaluation Prior to Biologic Therapy

Clinical Otolaryngology, Volume 51, Issue 1, Page 144-152, January 2026.
ABSTRACT Objective Chronic rhinosinusitis (CRS) is prevalent and causes a great negative impact on quality of life. Primary antibody deficiency (PAD) is highly prevalent with CRS compared to the background population. There are efficient treatment options to consider when CRS is a symptom of PAD. The condition seems to be underdiagnosed.
Anita García Petersen, Kasra Zainali‐Gill, Carsten Schade Larsen, Christian Nielsen, Therese Ovesen   +4 more
wiley   +1 more source

Phenotypic Remodeling of γδ T Cells in Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyposis. [PDF]

Medicina (Kaunas)
Bogović V, Štefanić M, Milanković SG, Zubčić Ž, Mihalj H, Tokić S, Mihalj M.   +6 more
europepmc   +1 more source

The Major Role of Type 2 Inflammation in Asthma: From the Perspective of Immunological Mechanism

BioMed Research International, Volume 2026, Issue 1, 2026.
Asthma is a heterogeneous disease that affects individuals of diverse age groups globally and exhibits variable responses to different treatments. Type 2 inflammation contributes to the pathogenesis of asthma through the production of cytokines IL‐4, IL‐5, and IL‐13, thereby inducing characteristic features of asthma such as elevated eosinophil levels ...
Lanying Cheng, Lihong Sun, Baisakhi Banerjee   +2 more
wiley   +1 more source

Nasal Cytology Is Useful for Evaluating and Monitoring the Therapeutic Response to Biologics in Chronic Rhinosinusitis with Nasal Polyposis. [PDF]

Biomedicines
Piatti G, Battilocchi L, Cozzi A, Gaini LM, Aldè M, Pignataro L, Torretta S.   +6 more
europepmc   +1 more source