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Adult chronic rhinosinusitis

Nature Reviews Disease Primers, 2020
Chronic rhinosinusitis (CRS) occurs in >10% of the adult population in Europe and the USA and can be differentiated into CRS without nasal polyps and CRS with nasal polyps (CRSwNP). Both phenotypes are characterized by a high disease burden and an overlapping spectrum of symptoms, with facial pain and loss of smell being the most differentiating. Great
Bachert, Claus   +8 more
semanticscholar   +5 more sources

Chronic Rhinosinusitis

The Journal of Allergy and Clinical Immunology: In Practice, 2013
A 50-year-old woman with nonallergic rhinitis, asthma, and aspirin intolerance presented with worsening symptoms of nasal congestion, purulent drainage, and anosmia. Nasal polyps were visualized on anterior rhinoscopy, and there was evidence of chronic rhinosinusitis (CRS) on imaging studies during work-up for another medical condition.
Christopher J, Ocampo, Leslie C, Grammer
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Chronic Rhinosinusitis

DeckerMed Otolaryngology, 2021
Chronic sinusitis (CRS) is a long-standing mucosal inflammatory disease of the sinonasal tract that results in significant impairment in patient quality of life. The pathogenic determinants of disease include chronic mucosal inflammation, local microbial colonization, and mucociliary dysfunction. A thorough understanding of this tripartite model allows
Abdulaziz Abushaala, Hisham S Khalil
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A comparative analysis of endoscopic sinus surgery versus biologics for treatment of chronic rhinosinusitis with nasal polyposis

International Forum of Allergy and Rhinology, 2022
Comparative effectiveness research between endoscopic sinus surgery (ESS) and biologic therapy for severe chronic rhinosinusitis with nasal polyposis (CRSwNP) is a nascent field as new therapeutic modalities become clinically available.
A. Miglani   +4 more
semanticscholar   +1 more source

Benralizumab effect on severe chronic rhinosinusitis with nasal polyps (CRSwNP): A randomized double‐blind placebo‐controlled trial

Clinical and Experimental Allergy, 2021
Chronic rhinosinusitis with nasal polyps (CRSwNP) can be a severe and debilitating disease associated with significant morbidity, loss of smell, sinus pressure and asthma exacerbations.
J. Tversky, A. Lane, A. Azar
semanticscholar   +1 more source

Highlights in the advances of chronic rhinosinusitis

Allergy. European Journal of Allergy and Clinical Immunology, 2021
Chronic rhinosinusitis (CRS) is a complex upper airway inflammatory disease with a broad spectrum of clinical variants. As our understanding of the disease pathophysiology evolves, so too does our philosophy towards the approach and management of CRS ...
Xinni Xu   +3 more
semanticscholar   +1 more source

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