Results 51 to 60 of about 45,136 (281)

Early and Sustained Improvements in Sense of Smell With Tezepelumab Treatment in Patients With Chronic Rhinosinusitis With Nasal Polyps (WAYPOINT)

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Loss of smell is a principal symptom of chronic rhinosinusitis with nasal polyps (CRSwNP), affecting health‐related quality of life and posing a safety hazard. Methods WAYPOINT (NCT04851964), a phase 3, multicenter trial in adults with uncontrolled CRSwNP, randomized patients 1:1 to receive tezepelumab 210 mg or placebo ...
Joaquim Mullol, Joseph K. Han, Tanya M. Laidlaw, Claire Hopkins, Anju T. Peters, Oliver Pfaar, Martin Desrosiers, Stella E. Lee, Andrew P. Lane, Claudia Chen, Yun Chon, Sandhia S. Ponnarambil, Andrew Foster, Andrew W. Lindsley, Christopher S. Ambrose   +14 more
wiley   +1 more source

Impedance‐Controlled Multipoint Radiofrequency Ablation for Chronic Rhinitis: A Randomized Controlled Trial

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The purpose of this randomized controlled trial (RCT) was to demonstrate that posterior nasal nerve ablation treatment with the NEUROMARK System is superior to a sham control procedure in patients with chronic rhinitis. Methods In this prospective, multicenter, single‐blinded, superiority RCT, 132 participants were randomized 2:1 to
Masayoshi Takashima, Randall A. Ow, Richard D. Thrasher, Ellen M. O'Malley, William R. Blythe, Omar G. Ahmed   +5 more
wiley   +1 more source

A study of cell membranes in nasal epithelial cells from patients with chronic rhinosinusitis with nasal polyps by means of a fluorescent probe [PDF]

, 2009
Aim. To assess the state of membranes in nasal epithelial cells obtained from the patients with chronic rhinosinusitis with nasal polyps (CRSwNP) with the help of the fluorescent probe 2-(2ʹ-ОН-phenyl)-5-phenyl-1,3-oxazole. Methods. The state of membrane
Onishchenko, A. I., Tkachenko, A. S., Nakonechna, O. A., Korniyenko, Y. M., Ryshchenko, I. M., Tsygankov, A. V., Posokhov, Y. O.   +6 more
core   +2 more sources

Appropriate Medical Therapy Primarily Modifies Type 2 and Severity Biomarkers in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Appropriate medical therapy (AMT) is first‐line treatment for patients with chronic rhinosinusitis (CRS). We evaluated inflammatory structure, treatment‐induced changes, and biomarker‐outcome associations in AMT‐managed patients. Methods Fifty‐one CRS patients were evaluated before and after AMT which included a combination of oral ...
Asher C. Park, Brooke N. Gleason, Eli Stein, Saied Ghadersohi, Atsushi Kato, Stephanie Shintani‐Smith, David B. Conley, Kevin C. Welch, Robert C. Kern, Bruce K. Tan   +9 more
wiley   +1 more source

Impact of chronic rhinosinusitis on the audiological profile of patients attending Lagos State University Teaching Hospital

The Egyptian Journal of Otolaryngology
Background Chronic rhinosinusitis is a common disease in Otorhinolaryngologic practice worldwide and in Nigeria. Its adverse effect on the quality of life has been well documented, and these reports focus on the nasal symptoms. There have been reports of
Adeola Lucy Sanda, Vincent Abimbola Adekoya, Olubukola Abimbola Fasina, Adeyemi Aderoju Adesanya, Clement Chukwuemeka Nwawolo   +4 more
doaj   +1 more source

Changes of the airway reactivity in patients with rhinosinusitis

Acta Medica Martiniana, 2022
Rhinosinusitis is one of the most common conditions in primary and secondary care all over the world. Rhinosinusitis together with asthma and gastroesophageal reflux disease represent the most common causes of chronic cough.
Miroslava Lucanska, Andrej Hajtman, Renata Pecova   +2 more
doaj   +1 more source

The Value of Multiple Medication Trials Prior to Balloon Sinuplasty in the Management of Chronic Sinonasal Disease

International Archives of Otorhinolaryngology, 2023
Introduction In patients with chronic rhinosinusitis, conservative interventions with extended medical trials are often attempted prior to procedural treatment.
Anand G. Shah, Macaulay Ojeaga, Josephine Novak, Vincent Honrubia   +3 more
doaj   +1 more source

Fungal speciation using quantitative polymerase chain reaction (QPCR) in patients with and without chronic rhinosinusitis. [PDF]

, 2006
Objectives/hypothesisThe objectives of this study were to determine the mycology of the middle meatus using an endoscopically guided brush sampling technique and polymerase chain reaction laboratory processing of nasal mucous; to compare the mycology of ...
Goldberg, Andrew N, Murr, Andrew H, Vesper, Stephen   +2 more
core  

A case-control study of medical, psychological and socio-economic factors influencing the severity of chronic rhinosinusitis [PDF]

, 2016
BACKGROUND: Chronic rhinosinusitis (CRS) is a common and debilitating disorder. Little is known about the epidemiology of this disease. The aims of the study were to identify differences in socio-economic variables and quality of life between patients ...
Anari, Shahram, Clark, Allan, Coombes, Emma, Erskine, Sally, Farboud, Amir, Hopkins, Claire, Kara, Naveed, Philpott, Carl, Salam, Mahmoud, Sunkaraneni, Vishnu   +9 more
core   +1 more source

Dupilumab Beyond the Airway: Decreased Morbidity in a Real‐World Analysis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Post hoc analyses of clinical trials have characterized dupilumab's adverse effects, yet the real‐world impact in chronic rhinosinusitis with nasal polyps (CRSwNP) and asthma is not well described. This study aims to characterize the risks of lymphoma, cardiovascular events, eosinophilia, joint pain, inflammatory arthritis, and ...
Emma J. Anisman, Spencer Short, Emma Tam, Benjamin F. Bitner, Abdulghafoor Alani, Marc Rosen, Mindy Rabinowitz, Damaris Pena Evertz, Elina Toskala, Gurston G. Nyquist   +9 more
wiley   +1 more source