Results 61 to 70 of about 45,136 (281)

Herpes viruses and human papilloma virus in nasal polyposis and controls

Brazilian Journal of Otorhinolaryngology, 2015
INTRODUCTION: Chronic rhinosinusitis with nasal polyps is a multifactorial disease entity with an unclear pathogenesis. Contradictory data exist in the literature on the potential implication of viral elements in adult patients with chronic ...
Dimitrios Ioannidis, Vasileios A. Lachanas, Zoe Florou, John G. Bizakis, Efthymia Petinaki, Charalampos E. Skoulakis   +5 more
doaj   +1 more source

Effect of Budesonide Nasal Irrigation in Patients With Chronic Rhinosinusitis With Nasal Polyps Without Prior Sinus Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Study

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background The indication for nasal irrigation with corticosteroids after sinus surgery in patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) is well established, as surgery facilitates distribution throughout the sinonasal cavity.
Juliana Sant'Ana, Isabela Pontes, Caio Floriano, Renato Rios, Marlos Cortez, Marcel Miyake   +5 more
wiley   +1 more source

Profile of Rhinosinusitis Patients with Orbital Complications at the Ear, Nose, and Throat (ENT) Outpatient Unit, Dr. Soetomo General Academic Hospital, Surabaya, from January 2015 to April 2022

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Introduction: Rhinosinusitis is an inflammation of the mucosa of the nasal cavity and/or paranasal sinuses. The most common complication is orbital. The limited data available does not account for the high number of cases of rhinosinusitis.
Made Ayu Rheina Putri, Budi Sutikno, Yulia Primitasari, Puguh Setyo Nugroho   +3 more
doaj   +1 more source

Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis [PDF]

, 2014
CFTR is a dynamically regulated anion channel. Intracellular WNK1-SPAK activation causes CFTR to change permeability and conductance characteristics from a chloride-preferring to bicarbonate-preferring channel through unknown mechanisms.
Alkaade, Samer, Aloe, Amy, Amann, Stephen T., Anderson, Michelle A., Bahar, Ivet, Baillie, John, Banks, Peter A., Barmada, M. Michael, Brand, Randall E., Conwell, Darwin, Cote, Gregory, Gardner, Timothy B., Gelrud, Andres, General, Ignacio, Jung, Jinsei, Kienholz, Michelle L., LaRusch, Jessica, Lawrence, Christopher, Lee, Min Goo, Lewis, Michele D., North American Pancreatitis Study Group, Park, Hyun Woo, Romagnuolo, Joseph, Sandhu, Bimaljit, Slivka, Adam, Whitcomb, David C., Yadav, Dhiraj   +26 more
core   +4 more sources

Rationale of New Grading System: Central Compartment Atopic Disease

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Central compartment atopic disease (CCAD) has recently been recognized as a distinct phenotype within the spectrum of type 2–dominant chronic rhinosinusitis (CRS). Although international guidelines highlight polypoid changes in the central nasal cavity, standardized diagnostic and classification criteria are still lacking.
Ramón Moreno‐Luna, Carmen Palma‐Martínez, Serafin Sánchez‐Gómez, Isam Alobid, Daniel Martin‐Jimenez, José Miguel Villacampa‐Aubá, Christian Calvo‐Henríquez, Alfonso Del Cuvillo, Alfonso Santamaría‐Gadea, Jaime González‐García, Richard J. Harvey, John M. DelGaudio   +11 more
wiley   +1 more source

Cost Utility Analysis of Fluticasone Exhalation Delivery System Versus Budesonide Nasal Irrigation for Chronic Rhinosinusitis With Nasal Polyps

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is managed after sinus surgery with topical corticosteroids. Given limited distribution of nasal steroid sprays, patients have the option of either steroid nasal irrigation (SNI) or exhalation delivery system with fluticasone (EDS‐FLU).
Daniel Xiao, Martin J. Citardi, William C. Yao, Amber U. Luong   +3 more
wiley   +1 more source

Biologics for the treatment of chronic rhinosinusitis with nasal polyps : state of the art [PDF]

, 2019
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complex upper airway disease affecting up to 11% of the population of Western Europe. In these western countries, 85% of the CRSwNP disease reveals a type 2 inflammatory pattern. In the last 15 years,
Bachert, Claus, Ren, Lei, Zhang, Luo, Zhang, Nan   +3 more
core   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

Dosing Interval Extension of Dupilumab in CRSwNP: Five‐Year Real World Outcomes

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent, often Type 2‐mediated inflammatory disease that markedly impairs quality of life. While dupilumab provides rapid improvement, there is limited evidence on long‐term outcomes beyond 2 years, and the clinical impact of dosing‐interval extension remains unclear.
Nicholas J. Campion, Dioni‐Pinelopi Petsiou, Florian C. Fally, Karina Berbalk, Noah F. Melamed, Aldine Tu, Christina Morgenstern, Fana Alem Kidane, Mohammed Zghaebi, Linda Liu, Minghao Pan, Tina J. Bartosik, Victoria Stanek, Katarina Gangl, Julia Eckl‐Dorna, Sven Schneider   +15 more
wiley   +1 more source

Expression of Pendrin Periostin in Allergic Rhinitis Chronic Rhinosinusitis

Allergology International, 2012
Background: : Pendrin and periostin are newly identified mediators of the inflammatory process. The expression of these proteins in human sinonasal tissue and their roles in allergic rhinitis and chronic rhinosinusitis remain to be elucidated. This study
Akihiro Ishida, Nobuo Ohta, Yusuke Suzuki, Seiji Kakehata, Kimihiro Okubo, Hiroki Ikeda, Hiroshi Shiraishi, Kenji Izuhara   +7 more
doaj   +1 more source