Results 61 to 70 of about 32,996 (302)

The Application Value of Bronchoalveolar Lavage Fluid Metagenomic Next‐Generation Sequencing in Moderate‐to‐Severe Bronchiectasis

Journal of Clinical Laboratory Analysis, EarlyView.
This study analyzed the clinical data of 52 patients with moderate‐to‐severe bronchiectasis who were admitted to our hospital. It explored the diagnostic value of bronchoalveolar lavage fluid (BALF) metagenomic next‐generation sequencing (mNGS) in identifying infectious pathogens in patients with moderate‐to‐severe bronchiectasis, and clarified the ...
Jiachun Li, Qiuping Quan, Junshan Chen, Xiaoyun Jian, Weijie Zhan, Jingmin Wang, Rongbin Jiang   +6 more
wiley   +1 more source

Gentamicin Nasal Irrigation in Children with Chronic Rhinosinusitis: A Retrospective Cohort of 38 Patients

Siriraj Medical Journal, 2014
Background: Chronic rhinosinusitis is a common problem in patients with allergic rhinitis or antibody deficiency. Topical antibiotic therapy for chronic sinusitis has been shown to improve symptoms and quality of life in adults.
Suruthai Kurasirikul, Orathai Jirapongsananurak, Pakit Vichyanond, Nualanong Visitsunthorn   +3 more
doaj  

Eosinophilic chronic rhinosinusitis

Allergology International, 2019
Eosinophilic chronic rhinosinusitis (ECRS) is a subgroup of chronic rhinosinusitis with nasal polyps (CRSwNP), which is associated with severe eosinophilic infiltration and intractable. Its symptoms include dysosmia, nasal obstruction, and visous nasal discharge.
Shigeharu Fujieda, Yoshimasa Imoto, Yukinori Kato, Takahiro Ninomiya, Takahiro Tokunaga, Toshiki Tsutsumiuchi, Kanano Yoshida, Masanori Kidoguchi, Tetsuji Takabayashi   +8 more
openaire   +3 more sources

The validated French CFAbd‐Score reveals a lower burden of gastrointestinal symptoms in patients on Elexacaftor/Tezacaftor/Ivacaftor

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Multiorgan abdominal involvement is a hallmark of Cystic fibrosis (CF). The CFAbd‐Score© is the first CF‐specific gastrointestinal patient reported outcome‐measure (PROM) developed following FDA‐guidelines. The PROM has proved to sensitively differentiate people with CF (pwCF) from healthy controls (HC).
Isabelle Sermet‐Gaudelus, Pauline Sadrieh, Anne Sophie Bonnel, Raphael Enaud, Nathalie Wizla, Jeanne Languepin, Ambre Nangui, Audrey Deelawon, Johanna Rave, Samira Dabelow, Anton Barucha, Carlos Zagoya, Franziska Duckstein, Jochen Georg Mainz   +13 more
wiley   +1 more source

Immunopathology of chronic rhinosinusitis

Allergology International, 2015
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local inflammation of the upper airways and sinuses which persists for at least 12 weeks. CRS can be divided into two phenotypes dependent on the presence of nasal polyps (NPs); CRS with NPs (CRSwNP) and CRS without NPs (CRSsNP).
openaire   +3 more sources

Dupilumab as an effective therapy for eosinophilic esophagitis in pediatric patients weighing less than 15 kilograms

JPGN Reports, EarlyView.
Abstract Objectives Eosinophilic esophagitis (EoE) is a type 2 cytokine‐mediated chronic inflammatory condition leading to esophageal dysfunction. Dupilumab blocks IL‐4 and IL‐13 signaling, which are key inflammatory mediators in EoE and other allergic disorders.
Sindhura Kasturi, Tanaz Danialifar, Thirumazhisai Gunasekaran, Nick Shillingford, Paul Zamiara, Vrinda Bhardwaj, Melinda Braskett   +6 more
wiley   +1 more source

Intranasal glucocorticosteroids for the complex treatment of patients with chronic diseases of the nose and paranasal sinuses

Медицинский совет, 2020
Intriduction. Chronic rhinitis and rhinosinusitis noticeably deteriorate the patients’ quality of life and lead to the accompanying upper airway pathology development.
P. A. Kochetkov, V. A. Svistushkin, E. S. Shchennikova   +2 more
doaj   +1 more source

The Microbiome and Chronic Rhinosinusitis

Immunology and Allergy Clinics of North America, 2020
Chronic rhinosinusitis (CRS) is persistent inflammation and/or infection of the nasal cavity and paranasal sinuses. Recent advancements in culture-independent molecular techniques have enhanced understanding of interactions between sinus microbiota and upper airway microenvironment.
Do-Yeon, Cho, Ryan C, Hunter, Vijay R, Ramakrishnan   +2 more
openaire   +3 more sources

Alveolar Extracellular Vesicles May Protect Some Patients With Chronic Aspiration From Pneumonia

The Laryngoscope, EarlyView.
A subset of patients with chronic aspiration appear to be relatively protected against pneumonias. This prospective observational study examines the alveolar fluid of patients with chronic aspiration with and without pneumonia. We found relatively little difference in classical cytokine levels but a difference in both the level and protein composition ...
James T. Ross, Nina W. Zhao, Dino Petrov, Ching‐Wen Lin, Alyssa Bellini, Neona Lowe, Bryan Nguyen, Dustin Hadley, Randy P. Carney, Anamaria J. Robles, Rachael A. Callcut, Peter C. Belafsky   +11 more
wiley   +1 more source

Chronic rhinosinusitis and neuropeptides

Swiss Medical Weekly, 2003
The nose is an air conditioner and is involved in the protection of the lower airways against inhalation of exogenous particles and airborne irritants. The nasal mucosa is therefore densely innervated by sensory nerves containing several neuropeptides. In the airways, activation of sensory C and A? fibres leads to the release of multiple neuropeptides.
openaire   +3 more sources