Results 81 to 90 of about 32,996 (302)

Biologics for chronic rhinosinusitis

Cochrane Database of Systematic Reviews, 2019
This living systematic review is one of several Cochrane Reviews evaluating the medical management of patients with chronic rhinosinusitis. Chronic rhinosinusitis is common. It is characterised by inflammation of the nasal and sinus linings, nasal blockage, rhinorrhoea, facial pressure/pain and loss of sense of smell.
Chong, Lee-Yee, Piromchai, Patorn, Sharp, Steve, Snidvongs, Kornkiat, Philpott, Carl, Hopkins, Claire, Burton, Martin J.   +6 more
openaire   +6 more sources

Elexacaftor–Tezacaftor–Ivacaftor Reduces Revision Sinus Surgery in People With Cystic Fibrosis

The Laryngoscope, EarlyView.
Elexacaftor–tezacaftor–ivacaftor (ETI) was associated with a significant decrease in the frequency and rate of endoscopic sinus surgeries in patients with cystic fibrosis. These findings suggest an improvement in CF‐related chronic rhinosinusitis outcomes following ETI and may influence future CF treatment decisions.
Amy Lin, Makanko Komara, Isaac Kistler, Zheng Hong Tan, Meredith Lind, Kavitha Kotha, Tendy Chiang   +6 more
wiley   +1 more source

Genetic correlation between chronic sinusitis and autoimmune diseases

Frontiers in Allergy
ObjectiveThe association between autoimmune diseases and chronic rhinosinusitis in observational studies remains unclear. This study aimed to explore the genetic correlation between chronic rhinosinusitis and autoimmune diseases.MethodsWe employed ...
Enze Wang, Yingxuan Sun, He Zhao, Meng Wang, Zhiwei Cao   +4 more
doaj   +1 more source

Significant polyomic and functional upregulation of the PAPP‐A/IGFBP‐4/5/IGF‐1 axis in chronic rhinosinusitis with nasal polyps [PDF]

, 2020
Sarina K. Mueller, Angela L. Nocera, Alan D. Workman, Towia A. Libermann, Simon T. Dillon, Achim Stegmann, Jochen Wurm, Heinrich Iro, Olaf Wendler, Benjamin S. Bleier   +9 more
openalex   +1 more source

Diagnosing Eosinophilic Chronic Rhinosinusitis in Excised Tissue Using Optical Coherence Tomography

The Laryngoscope, EarlyView.
This study evaluated whether optical coherence tomography (OCT) can quantify eosinophils in excised sinonasal tissue and diagnose eosinophilic chronic rhinosinusitis with nasal polyps (ECRSwNP). Counts of globules resembling eosinophils on OCT images strongly correlated with eosinophils per HPF on histology, with a cutoff of 45 globules on OCT imaging ...
Ido Badash, Michael Serafino, Adrian Correa, John S. Oghalai, Bozena Wrobel, Brian E. Applegate, Kevin Hur   +6 more
wiley   +1 more source

Orbital Complications of Acute Rhinosinusitis in Adulthood: Predictors of Outcome and Management

The Laryngoscope, EarlyView.
In a multicenter cohort of 213 adults with orbital complications of acute rhinosinusitis, 68% required surgery and the modified Chandler classification was the strongest predictor of treatment modality. While abscess‐related and type II complications frequently necessitated surgical management, final ophthalmologic outcomes were uniformly favorable ...
Alessandro Vinciguerra, Vittorio Rampinelli, Mario Turri‐Zanoni, Marco Ferrari, Marco Valentini, Alberto Daniele Arosio, Federico Raimondi, Florian Chatelet, Stefano Taboni, Davide Mattavelli, Alberto Schreiber, Fabio Sovardi, Matteo Barucco, Lorena Di Girolami, Piergiorgio Gaudioso, Antonio Daloiso, Giulia Danè, Umberto Tanzini, Nicola Tessari, Jessica Zuppardo, Kays Burak Cakir, Yetkin Zeki Yilmaz, Yasar Unlu, Andrea Ronchi, Stefania Gallo, Francesca De Bernardi, Vasileios Chatzinakis, Argyro Leventi, Fabio Pagella, Benjamin Verillaud, Giuseppe Mercante, Apostolos Karligkiotis, Mario Bussi, Cesare Piazza, Alperen Vural, Paolo Castelnuovo, Piero Nicolai, Maurizio Bignami, Christos Georgalas, Iacopo Dallan, Philippe Herman, Paolo Battaglia   +41 more
wiley   +1 more source

Prevalence, location and tomographic severity of chronic rhinosinusitis in adult patients with common variable immunodeficiency

Revista Alergia México, 2015
Background: Common variable immunodeficiency (CVID) is one of the most common antibody deficiencies in adults. The prevalence of respiratory infections have been reported in 75% vs 2-16% in general population.
Gabriela Angulo-Pérez, Eulalio Vivar-Acevedo, Alejandro Vargas-Aguayo, Eunice Giselle López-Rocha   +3 more
doaj   +1 more source

Cannabis Use and Risk of Chronic Rhinosinusitis and Sinus Surgery. [PDF]

Laryngoscope Investig Otolaryngol
ABSTRACT Objective While cannabis' link to asthma is well‐studied, its impact on CRS is less clear. This study explores the association between cannabis use and rates of new‐onset chronic rhinosinusitis (CRS), chronic rhinosinusitis with nasal polyps (CRSwNP), and functional endoscopic sinus surgery (FESS) rates.
Lee AJ, Liu MW, Kaelber DC, Chaaban MR.
europepmc   +2 more sources

Is Verapamil Effective for Treating Patients With Chronic Rhinosinusitis With Nasal Polyps? A Systematic Review. [PDF]

Clin Otolaryngol
ABSTRACT Objective Identify and summarise the evidence on the efficacy of low‐dose verapamil use for adult patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP). Methods Two reviewers independently searched the data sources until the 28th of December 2023.
Yin F, Ali H, Abdelhalim A, Elhassan HA.
europepmc   +2 more sources

Patient perspectives about participation in a chronic rhinosinusitis trial during the COVID pandemic: a qualitative study. [PDF]

, 2021
Jane Vennik, Clare McDermott, Samantha Williams, Carl Philpott, Mike Thomas, Paul Little, Anne GM Schilder, Claire Hopkins   +7 more
openalex   +1 more source