Results 101 to 110 of about 8,283 (190)
The International Guideline for the Definition, Classification, Diagnosis and Management of Urticaria
Allergy, Volume 81, Issue 8, Page 2582-2632, August 2026.ABSTRACT
This update and revision of the international guideline for urticaria was developed in accordance with the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is an initiative of the Global Allergy and Asthma Excellence Network (GA2LEN) and its Urticaria and ...Torsten Zuberbier, Zainab AbdulHameed Ansari, Amir H. Abdul Latiff, M. M. Abuzakouk, Maria Socorro Agcaoili‐De Jesus, Rosana C. Agondi, Mona Al‐Ahmad, Abdullah A. Alangari, H. Alhameli, Cesar D. Alonso Bello, Saad Alshareef, Salem Al‐Tamemi, Sabine Altrichter, Humaid Al Wahshi, S. Aquilina, M. Araújo, Rand Arnaout, Riccardo Asero, Barbara Ballmer‐Weber, Christine Bangert, Andrea Bauer, Moshe Ben‐Shoshan, Jonathan A. Bernstein, Carsten Bindslev‐Jensen, Mojca Bizjak, Isabelle Boccon‐Gibod, Hanna Bonnekoh, Laurence Bouillet, Knut Brockow, Zenon Brzoza, M. Bulatović Ćalasan, Adeeb Bulkhi, Thomas Buttgereit, Anette Bygum, Teresa Caballero, Oscar Calderon, R. Campos, Mauro Cancian, Emily Carne, Mary Anne Castor, Inmaculada Cerecedo, T. Çetinarslan, Ivan Cherrez‐Ojeda, N. Chkhikvadze, Herberto J. Chong‐Neto, Karen Choo, George Christoff, Chia‐Yu Chu, K. Ciupka, Niall Conlon, Célia Costa, Timothy J Craig, Paulo Criado, Inna Danilycheva, Razvigor Darlenski, Erika De Arruda Chaves, Laurence de Montjoye, M.‐S. Doutre, Aurelie Du‐Thanh, Didier Ebo, S. Elkhalifa, S. Elmariah, Tariq El‐Shanawany, Luis F. Ensina, Ragip Ertaş, Roberta Fachini Jardim Criado, Marta Ferrer, Silvia Ferrucci, Jie Shen Fok, Daria Fomina, Luz Fonacier, Ghada Fouda, I. Francescantonio, Atsushi Fukunaga, César A. Galvan Calle, Elizabeth Garcia, Krisztian Gáspár, Aslı Gelincik, Songmei Geng, Kiran Godse, Margarida Gonçalo, Maia Gotua, C. Grattan, Martine Grosber, Guillermo Guidos Fogelbach, Mar Guilarte, R. Guillod, Eckard Hamelmann, Jason Hawkes, Koremasa Hayama, Ruben Heuer, Michihiro Hide, Wolfram Hoetzenecker, Naoko Inomata, Hye‐Ryun Kang, Allen P. Kaplan, Alexander Kapp, M. Karam, Alicja Kasperska‐Zajac, Constance H. Katelaris, Aharon Kessel, Maryam Khoshkhui, Brian Kim, Tamar Kinaciyan, Emek Kocatürk, Marta Kolacinska‐Flont, Pavel Kolkhir, George N. Konstantinou, Mitja Kosnik, Dorota Krasowska, Kanokvalai Kulthanan, Muthu S. Kumaran, Izabela Kuprys‐Lipinska, Moisés Labrador, Jose Ignacio Larco, Désirée Larenas‐Linnemann, Elena Latysheva, E. Lazaridou, Philip H. Li, H. Lima, Undine Lippert, Markus Magerl, Michael Makris, João Alves Marcelino, Angelo V. Marzano, Iris Medina, Raisa Meshkova, D. Micallef, Ramzy Mohammed Ali, Charlotte G. Mortz, Melba Munoz, Hanneke N. G. Oude Elberink, Alla Nakonechna, Iman Nasr, Alexander Nast, Elena Netchiporouk, Eustachio Nettis, Sandra Nieto, Isabel Ogueta Canales, T.‐L. Okas, Raquel L. Orfali, Esen Özkaya, Claudio Parisi, A. Pennitz, Ruby Pawankar, Manuel P. Pereira, Jonny Peter, Elena Petkova, P. D. Pigatto, Indrashis Podder, T. Popov, Grzegorz Porebski, Polina Pyatilova, German D. Ramon, Hector A. Ratti Sisa, Marysia Stella Recto, Krista Ress, Katie Ridge, Marc Riedl, Carla Ritchie, Nelson Rosario Filho, Isabel Rosmaninho, Michael Rudenko, Maia Rukhadze, Krzysztof Rutkowski, Vito Sabato, Umit M. Sahiner, Sarbjit Saini, F. Saleh Al Sabbagh, Andac Salman, Fulvio Salvo, Jorge Sanchez, A. Santucci, Sibylle Schliemann, Peter Schmid‐Grendelmeier, Bulent E. Sekerel, Faradiba Serpa, Farrukh Sheikh, J. Sheikh, H. Shendi, Frank Siebenhaar, M. Sonomjamts, Angele Soria, Bernardo Sousa Pinto, Maria Staevska, Petra Staubach, M. Stephan, Katarina Stevanovic, Luca Stingeni, Marcin Stobiecki, Özlem Su Küçük, Gordon Sussman, Andrea Szegedi, Shunsuke Takahagi, Akio Tanaka, Natasa Teovska Mitrevska, Simon Francis Thomsen, Elias Toubi, Fragkiski Tsatsou, Murat Turk, Zahava Vadasz, Anna Valerieva, Solange Valle, Martijn van Doorn, Beatriz Veleiro Perez, Carolina E. Vera Ayala, Christian Vestergaard, Rafael J. Vieira, C. W. Maruta, Bettina Wedi, Ricardo N. Werner, Evelyn Wen Yee Yap, Paraskevi Xepapadaki, Yi‐Kui Xiang, Young‐Min Ye, Patrick Yong, Gil Yosipovitch, Anna Zalewska‐Janowska, Christoph Zeyen, Zuotao Zhao, Martin Metz, Ana M. Giménez‐Arnau +221 morewiley +1 more sourceEndotypes of chronic spontaneous urticaria and angioedema
Journal of Allergy and Clinical ImmunologyThe current understanding of chronic spontaneous urticaria (CSU) suggests that a complex network of inflammatory pathways is involved in its pathogenesis. Recent development highlighted autoimmunity as one of the key pathogenic mechanisms of CSU. Two endotypes, type I autoallergic (associated with IgE antibodies against autoantigens) and type IIb ...Dennis, Wong, Susan, Waserman, Gordon L, Sussman +2 moreopenaire +2 more sourcesIron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
Allergy, Volume 81, Issue 8, Page 2675-2712, August 2026.ABSTRACT
Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni +19 morewiley +1 more sourceIncidence and Early‐Life Risk Factors for Food Allergy in a Spanish Birth Cohort
Acta Paediatrica, Volume 115, Issue 8, Page 1654-1662, August 2026.ABSTRACT Aim
The prevalence of food allergy has increased in recent decades. We aimed to determine the cumulative incidence of food allergy in early childhood and to identify associated risk factors. Methods
We conducted a prospective birth cohort study including 1006 newborns recruited over one year at a single hospital in Spain and followed until 4 ...Jorge García‐Ezquiaga, Patricia Torija‐Berzal, Sergio Quevedo‐Teruel, Teresa Bracamonte‐Bermejo, Patricia Alonso‐López, Luis Echeverría‐Zudaire, María Luz García‐García +6 morewiley +1 more sourceUpdate on the Treatment of Chronic Spontaneous Urticaria
DrugsChronic spontaneous urticaria (CSU) is a mast cell-mediated skin disease that presents with wheals, angioedema, or both for more than 6 weeks. Less than 10% of patients have complete control of their CSU (the main goal of CSU treatment) with second generation H1-antihistamines, the first-line treatment.Pavel Kolkhir, Jie Shen Fok, Emek Kocatürk, Philip H. Li, Tiia-Linda Okas, Joao Marcelino, Martin Metz +6 moreopenaire +2 more sourcesBeyond Histamine: Mast Cell‐Neuron Communication in Chronic Pruritic and Pain Disorders
Experimental Dermatology, Volume 35, Issue 8, August 2026.ABSTRACT
Chronic pruritic and cutaneous pain disorders are increasingly recognized as neuroimmune conditions driven by dynamic interactions between immune and sensory systems. While histamine has historically dominated models of mast cell‐mediated itch, accumulating evidence indicates that non‐histaminergic pathways are central to chronic disease.Tomer Kagan, Gil Yosipovitchwiley +1 more sourceAddiction and chronic skin diseases: A Pan‐European study on prevalence, associations and patient impact
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 8, Page 1392-1405, August 2026.This pan‐European study reveals high rates of addiction in patients with chronic skin diseases. Smoking, alcohol, drug use, gambling, and internet addiction were prevalent and associated with quality of life, demographics, and region. The findings support integrating addiction screening into dermatologic care to improve outcomes.Stefanie Ziehfreund, Magdalena Saak, Alisa Schaal, Roxana Mazilu, Emmanuel Mahé, Carla Hajj, Emma K. Johansson, Josefin Lysell, Gunnthorunn Sigurdardottir, Franz J. Legat, Catherina Koch, Astrid Schmieder, Caroline Glatzel, Brian Kirby, Emily Pender, Anna Zalewska‐Janowska, Katarzyna Tomaszewska, Giulia Ciccarese, Pia Lauriola, Michael J. Boffa, Stephanie Farrugia, Anna Caroline Pilz, Franziska Schauer, Magdalena Trzeciak, Weronika Zysk, Krisztián Gáspár, Andrea Szegedi, Giovanni Damiani, Andrea Carugno, Ilona Hartmane, Ingmars Mikazans, Skaidra Valiukeviciene, Livija Petrokaite, Jacek C. Szepietowski, Beata Jastrząb, Petra Staubach, Suzana Ljubojević Hadžavdić, Daška Štulhofer Buzina, Christian Posch, Jakob Jochmann, Antonia Wiala, Ludwig Scheffenbichler, Emanuele Trovato, Laura Calabrese, Gyula Laszlo Fekete, Pavel Chernyshov, Lidiia Kolodzinska, Julia Welzel, Karisa Thölken, Julia‐Tatjana Maul, Lara Valeska Maul, Damian Meyersburg, Stephanie Bowe, Cathal O. Connor, Razvigor Darlenski, Stephan Traidl, Christian Vestergaard, Elena Lucía Pinto‐Pulido, Maria Polina Konstantinou, Eszter Szlávicz, Kristine Heidemeyer, Nikhil Yawalkar, Hanka Agnes Caroline Lantzsch, Aleksandra Soplinska, Anna‐Theresa Seitz, Tiago Torres, Zenon Brzoza, Ana Sanader Vučemilović, Liana Manolache, Nina Magnolo, Emanuele Scala, Kilian Eyerich, Tilo Biedermann, Alexander Zink +73 morewiley +1 more sourceFamily quality‐of‐life burden in chronic spontaneous urticaria: A multicentre study
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 8, Page 1406-1419, August 2026.Poor control of chronic spontaneous urticaria (CSU) significantly worsens family members' quality of life, especially in emotional, physical, and social domains. Higher disease severity was linked to increased caregiving burden and household expenditures, highlighting the need for family‐centred CSU care and support across diverse global populations ...Beatrice Martinez Zugaib Abdalla, Roberta Fachini Jardim Criado, Kanokvalai Kulthanan, Emek Kocatürk, Ivan Cherrez‐Ojeda, Ana Maria Giménez‐Arnau, Marcus Maurer, Luis Felipe Ensina, Jonathan A. Bernstein, Michihiro Hide, Sergio Duarte Dortas Junior, Solange Oliveira Rodrigues Valle, Gabriela Dias, Paraskevi Xepapadak, Priyanshi Dangi, Indrashis Podder, Vesna Trajkova, Natasa Teovska Mitrevska, Iman Hamed Nasr, Bushra Al Hinai, Joanna Bartosińska, Dorota Krasowska, Paulina Szczepanik‐Kułak, Hilal Gungor, Deniz Ozceker, Kübra Çiçek, Esen Özkaya, Yasemin Erdem, Mücahit Ergün, Mustafa Tosun, Rabia Oztas Kara, Jie Li, Anastasia Allenova, Paulo Ricardo Criado +33 morewiley +1 more sourceMyeloid and Mast Cell Progenitors Are Elevated in Atopic Dermatitis
JID InnovationsChronic spontaneous urticaria and atopic dermatitis (AD) are chronic skin disorders characterized by itch. Although mast cells play an integral role in the pathogenesis of chronic spontaneous urticaria, their role in AD is unclear, having a contributory ...Katie Ridge, Barry Moran, Mark A. Little, Cliona O’Farrelly, Jean Dunne, Julianne Clowry, Clodagh Loftus, Conor M. Finlay, Alan D. Irvine, Niall Conlon +9 moredoaj +1 more sourceOX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 8, Page 1318-1331, August 2026.OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet +4 morewiley +1 more source
