Results 111 to 120 of about 10,054 (222)

Evaluating Basophil Histamine Content as a Biomarker for Omalizumab Responsiveness in Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, EarlyView.
Ditte Georgina Zhang, Katrine Baumann, Clive Grattan, Per Stahl Skov, Simon Francis Thomsen   +4 more
wiley   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Omalizumab in the Treatment of Urticaria

167176Omalizumab is a humanized mouse monoclonal IgG1 antibody directed against the third heavy chain domain of IgE. It has been approved for moderate to severe asthma since 2003, for adults and adolescents with chronic spontaneous urticaria unresponsive
Zuberbier, Torsten, Grattan, Ceh E.H., Maurer, Marcus, Dörr, Tamara   +3 more
core   +1 more source

Autologous Serum Therapy in Recalcitrant Chronic Spontaneous Urticaria: Experience from Three Dermatology Clinics in Malaysia

Indian Journal of Dermatology
Autohemotherapy is a commonly used treatment for recalcitrant chronic urticaria in some countries. Herein we report our experience using autologous serum therapy in eight patients with recalcitrant chronic spontaneous urticaria.
Ingrid Ting Pao Lin, Nurul Izyan Ghazali, Yan Teo, Siaw Ling Lai, Mohammed Faizal Bakhtiar, Min Moon Tang   +5 more
doaj   +1 more source

Disease modification in chronic spontaneous urticaria

Allergy
AbstractChronic spontaneous urticaria (CSU) is a debilitating, inflammatory skin condition characterized by infiltrating immune cells. Available treatments are limited to improving the signs and symptoms. There is an unmet need to develop therapies that target disease‐driving pathways upstream of mast cell activation to inhibit or delay the progression
Marcus, Maurer, Pavel, Kolkhir, Manuel P, Pereira, Frank, Siebenhaar, Ellen, Witte-Händel, Karl-Christian, Bergmann, Hanna, Bonnekoh, Thomas, Buttgereit, Joachim W, Fluhr, Stefan, Frischbutter, Eva Maria, Grekowitz, Leonie, Herzog, Lea Alice, Kiefer, Karoline, Krause, Markus, Magerl, Melba, Muñoz, Sophia, Neisinger, Nicole, Nojarov, Samantha, Prins, Polina, Pyatilova, Aisté, Ramanauskaité, Jörg, Scheffel, Dorothea, Terhorst-Molawi, Regina, Treudler, Karsten, Weller, Torsten, Zuberbier, Martin, Metz   +26 more
openaire   +2 more sources

A Meta‐Analysis of Anti‐Thyroid Peroxidase Antibody and Omalizumab Response in Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, EarlyView.
Ju Hyun Lee, Min Jung Geum, Do‐Young Kim, Young‐Mi Ah, Yun Mi Yu   +4 more
wiley   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Neurotrophins: Are They Meaningful in Chronic Spontaneous Urticaria?

, 2021
Plasma neurotrophin levels are elevated in patients with allergic and autoimmune diseases. The present study was designed to investigate the serum neurotrophin levels in 42 patients displaying chronic spontaneous urticaria, as well as 22 healthy control ...
Buyukozturk, Suna, Akkor, Aytug, Ozseker, Ferhan, Eroglu, Hacer, Genc, Sema, Dal, Murat, Gelincik, Aslı, Depboylu, Bilge, Colakoglu, Bahattin, Erden, Sacide, Giris, Murat   +10 more
core  

The role of antibiotics in preventing surgical complications in periodontology and implant dentistry

Periodontology 2000, EarlyView.
Abstract Antibiotics are commonly prescribed in periodontal and implant surgeries, either before, during or after surgery, to prevent postoperative infection and reduce early implant failure. However, the potential benefits may be undermined by the risks of resistance and sensitization, thus requiring a strict indication for prescription.
Zhaozhao Chen, Lan‐Lin Chiou, Javier Calatrava, Hom‐Lay Wang   +3 more
wiley   +1 more source

Clinical Findings, Treatment Recommendations, and Outcome in Dogs Following Ingestion of a Single Unintended Dose of Trilostane: 403 Cases (2008–2023)

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To characterize the clinical signs and outcomes in dogs following ingestion of a single, unintended dose of trilostane. The secondary objective was to describe treatment recommendations given for this population. Design Retrospective evaluation of cases of canine trilostane exposure from February 2008 to August 2023. Setting Private,
Lindsey Summers, Jenny Schuett, Laura Stern   +2 more
wiley   +1 more source