Results 71 to 80 of about 5,345,179 (257)
Assessing the psychophysiological pathways that link chronic stress with increased vulnerability for ill health [PDF]
This programme of work investigated the psychophysiological pathways that link chronic stress with increased vulnerability for ill health. Data from study one indicated that atypical patterns of cortisol secretion, widely implicated in the aetiologies of
Lovell, Brian
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Post-effects of chronic emotional stress in rats
, 2004 The post-effects on humoral immune response and the level of norepinephrine of rats were analyzed following chronic emotional stress induced by randomly giving empty water bottles to rats during watering periods per day for 4 weeks.
W. W. Wang, W. J. Lin
core +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Preventing Chronic Disease (PCD) [PDF]
This collection of articles in Preventing Chronic Disease (PCD) brings together scientists and practitioners from the breadth of public health and the social sciences to demonstrate how geospatial perspectives can contribute to understanding and ...
core +2 more sources
Chronic Stress, 2019 Background Although several studies have examined risk factors for suicidal ideation among veterans, little is known about risk and protective factors for suicidal ideation in high-risk veteran samples. Thus, this study examined a broad range of risk and
Elizabeth Straus +4 more
doaj +1 more source
, 2017 How stress influences brain repair is an issue of considerable importance, as patients recovering from stroke are known to experience high and often unremitting levels of stress post-event.
Lin Kooi Ong +9 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Chronic Stress, 2019 The mechanisms underlying the antidepressant effects of ketamine in treatment-resistant depression are only partially understood. Reactivation of neural plasticity in prefrontal cortex has been considered critical in mediating the effects of standard ...
Ginetta Collo +2 more
doaj +1 more source
, 2019 Prolonged or repeated exposure to stress increases risk for a variety of psychological disorders, many of which are marked by dysfunction of corticolimbic brain regions.
Wellman, Cara Lynn +2 more
core +1 more source