Results 31 to 40 of about 10,388 (184)

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Single versus double drainage in chronic subdural hematomas treated with burr-holes

Revista Cubana de Medicina Militar, 2023
Introduction: Chronic subdural hematoma is a frequent type of intracranial hemorrhage. Treatment for symptomatic cases is generally surgical. Burr-hole completion is the method of choice.
Ernesto Enrique Horta-Tamayo, Luis Cesar Acosta-Gonzalez, Diana Rosa Ortega-Raez, Lazaro Noel Parra-Vidal, Martha Suarez-Cruz   +4 more
doaj  

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo, Sarah Araji, Weimin Bi, Seema R. Lalani   +3 more
wiley   +1 more source

A guide to neuromodulation in drug‐resistant epilepsy

Epileptic Disorders, EarlyView.
Abstract Neuromodulation is approved for the treatment of drug‐resistant epilepsy. It has been increasingly utilized over the past two decades with the approval of deep brain stimulation (DBS) and responsive neurostimulation (RNS) in addition to vagus nerve stimulation (VNS)—particularly in patients who are not deemed to be good resective surgical ...
Prachi Parikh, Irena Dolezawa, Manu Hegde, Lukas Imbach, Brian N. Lundstrom, Francesca Pizzo, Vikram R. Rao, Jaysingh Singh, Derek Southwell, Satsuke Watanabe, Birgit Frauscher   +10 more
wiley   +1 more source

Intracranial electroencephalographic approaches in the intensive care unit: Safety, feasibility, and coverage

Epilepsia, EarlyView.
Abstract Objective Nonconvulsive epileptic activity is common after acute brain injury and contributes to neuronal injury and poor outcomes. Although intracranial electroencephalography (iEEG) improves detection compared with surface EEG (suEEG), it currently relies on focal recordings of epileptic dynamics.
Steven Smeijers, Mariella Segreti, Anaïs Van Hoylandt, Jeroen Gijs, Johannes van Loon, Lauranne Scheldeman, Bart Depreitere, Tom Theys   +7 more
wiley   +1 more source

High‐frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development

Epilepsia, EarlyView.
Abstract Objective The development of posttraumatic epilepsy after traumatic brain injury (TBI) is potentially identifiable by measuring biomarkers of epileptogenesis, namely pathological high‐frequency oscillations (pHFOs). pHFOs are promising candidates, but it remains uncertain whether they can be detected early after TBI in clinical settings.
Kseniia Kriukova, Lin Li, Richard J. Staba, Misque Boswell, Tuba Asifriyaz, Rachel Thomas, James J. Gugger, Mohamad Shamas, Ramon Diaz‐Arrastia, Manuel Buitrago Blanco, Jerome Engel, Paul M. Vespa, Dominique Duncan, on behalf of the EpiBios4Rx investigators, Denes Agoston, Alicia K. Au, Michael Bell, Ben Churn, Jan Claassen, Ramon Diaz‐Arrastia, Jerome Engel, Brandon Foreman, Aristea Galanopoulou, Emily Gilmore, Martin Hunn, Nathalie Jette, Andrew Morokoff, Solomon L. Moshé, Terence O'Brien, Joshua Laing, Piero Perucca, Kristine H. O'Phelan, Asla Pitkanen, Eric Rosenthal, Frederick Willyerd, Lara Zimmermann, Ben Ellingson, Buitrago Blanco, Daniel Correa, Dana Harrar, Thomas P. Bleck, Brian Appavu, Aaron Struck, Baxter Allen, Inna Keselman, Jeff Kennedy, Victor Ferastraoaru, Ji Yeoun Yoo, Arthur W. Toga   +48 more
wiley   +1 more source

CHRONIC SUBDURAL HEMATOMA

Annals of Surgery, 1927
In this country the interest in chronic subdural hemorrhage was aroused by the report of Putnam and Cushing 1 in 1925. Curiously enough, at that time these authors could report but six cases from the Peter Bent Brigham Hospital records, although a very large amount of neurosurgical material passed through this clinic.
openaire   +3 more sources

History of Chronic Subdural Hematoma [PDF]

Korean Journal of Neurotrauma, 2015
Trephination or trepanation is an intentional surgical procedure performed from the Stone Age. It looks like escaping a black evil from the head. This technique is still used for treatment of chronic subdural hematoma (SDH). Now, we know the origin, pathogenesis and natural history of this lesion.
openaire   +2 more sources

Trial of Dexamethasone for Chronic Subdural Hematoma [PDF]

New England Journal of Medicine, 2020
Chronic subdural hematoma is a common neurological disorder mainly affecting older people.1 It consists of a collection of blood and blood breakdown products in the intracranial subdural space that liquefies over time; the inciting event often is minor head trauma; subsequent inflammation may play a role in the pathogenesis.2 The time of onset of ...
Hutchinson, Peter J., Edlmann, Ellie, Bulters, Diederik, Zolnourian, Ardalan, Holton, Patrick, Suttner, Nigel, Agyemang, Kevin, Thomson, Simon, Anderson, Ian A., Al-Tamimi, Yahia, Henderson, Duncan, Whitfield, Peter, Gherle, Monica, Brennan, Paul M., Allison, Annabel, Thelin, Eric P., Tarantino, Silvia, Pantaleo, Beatrice, Caldwell, Karen, Davis-Wilkie, Carol, Mee, Harry, Warburton, Elizabeth A., Barton, Garry, Chari, Aswin, Marcus, Hani J., King, Andrew T., Belli, Antonio, Myint, Phyo K., Wilkinson, Ian, Santarius, Thomas, Turner, Carole, Bond, Simon, Kolias, Angelos G., British Neurosurgical Trainee Research Collaborative and Dex-CSDH Trial Collaborators   +33 more
openaire   +5 more sources

Rapid Spontaneous Resolution of Contralateral Acute Subdural Hemorrhage Caused by Overdrainage of Chronic Subdural Hemorrhage [PDF]

Journal of Neurocritical Care, 2018
Background Since the first report of a rapidly resolved subdural hemorrhage (SDH) in 1986, few additional case reports have been presented in the literature. Case Report An 82-year-old female patient presented with a SDH over the left convexity.
Minwook Yoo, Jung-Soo Kim
doaj   +1 more source