Results 91 to 100 of about 84,576 (334)

Riociguat and the right ventricle in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension

European Respiratory Review, 2022
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are progressive diseases that can lead to right heart failure and death.
R. Benza, D. Langleben, A. Hemnes, A. Vonk Noordegraaf, S. Rosenkranz, T. Thenappan, P. Hassoun, I. Preston, S. Ghio, R. Badagliacca, C. Vizza, I. Lang, C. Meier, E. Grünig   +13 more
semanticscholar   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Should We Change the Target of Therapy in Pulmonary Hypertension?

Life, 2023
Despite the evolution of drug therapy in pulmonary arterial hypertension and the more aggressive treatment approach according to the guidelines, patients continue to have unacceptable mortality rates.
Panagiotis Karyofyllis, Eftychia Demerouti, Pavlos Habibis, Styliani Apostolopoulou, Eleftheria-Garyfallia Tsetika, Dimitrios Tsiapras   +5 more
doaj   +1 more source

Haemodynamic consequences of acute pulmonary embolism predict risk of CTPA‐related acute kidney injury

ESC Heart Failure, EarlyView.
The graphical abstract summarizes that normotensive APE patients with elevated NT‐proBNP levels and higher BOVA scores are at increased risk of AKI and should be closely monitored for renal injury during hospitalization. Abstract Introduction Computed tomography pulmonary angiography (CTPA) is an important study in the diagnosis of acute pulmonary ...
Anna M. Imiela, Michał Machowski, Bartosz Karolak, Olaf Wasilewski, Małgorzata Landowska, Aleksandra Żuk‐Łapan, Aleksandra Piech, Tomasz Cader, Małgorzata Wiśniewska, Bogdan Stelmach, Piotr Pruszczyk   +10 more
wiley   +1 more source

EmPHasis‐10 Health‐Related Quality of Life and Exercise Capacity in Chronic Thromboembolic Pulmonary Hypertension After Balloon Angioplasty

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Whether pulmonary hemodynamic parameters and functional capacity are associated with quality of life in patients with chronic thromboembolic pulmonary hypertension remains unknown.
Hayato Sakamoto, Ayumi Goda, Kazuki Tobita, Kaori Takeuchi, Hanako Kikuchi, Takumi Inami, Yuichi Tamura, Takashi Kohno, Shin Yamada, Kyoko Soejima, Toru Satoh   +10 more
doaj   +1 more source

Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension. [PDF]

, 2010
BACKGROUND: Coagulation factor VIII (FVIII) deficiency leads to haemophilia A. Conversely, elevated plasma levels are a strong predictor of recurrent venous thromboemboli and pulmonary hypertension phenotypes in which in situ thromboses are implicated ...
Angus, G, Birdsey, GM, Elderfield, K, Govani, FS, Laffan, MA, Manning, RA, Mauri, FA, Mollet, IG, Okoli, GN, Shovlin, CL   +9 more
core   +1 more source

Advances in balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension

Pulmonary Circulation, 2021
Balloon pulmonary angioplasty (BPA) is an emerging treatment option for patients with chronic thromboembolic pulmonary hypertension (CTEPH) who have inoperable, segmental/subsegmental disease, or residual disease after pulmonary endarterectomy.
E. Mahmud, M. Patel, Lawrence Ang, D. Poch   +3 more
semanticscholar   +1 more source

Doppler echocardiographic assessment of left ventricular diastolic function in chronic hypoxic rats [PDF]

, 2009
Little information is available on the mechanism of diastolic left ventricular (LV) dysfunction in patients with chronic respiratory disease complicated by hypoxia.
Itoh, Atsushi, Sano, Shunji, Tomita, Hideshi   +2 more
core   +1 more source

Exercise‐induced out‐of‐proportion increase in afterload and impaired right ventricular contractile reserve in HFpEF

ESC Heart Failure, EarlyView.
Non‐cardiac dyspnoea (n = 34, NCD) and heart failure with preserved ejection fraction (n = 34, HFpEF) patients were classified according to right heart catheterisation. Cardiovascular magnetic resonance derived right ventricular (RV) haemodynamic indices for afterload (Ea), contractility (Ees) and RV/pulmonary artery coupling (Ea/Ees) were evaluated ...
Jan Sebastian Wolter, Alexander Schulz, Torben Lange, Steffen D. Kriechbaum, Shelby Kutty, Johannes T. Kowallick, Julia M. Treiber, Andreas Rolf, Samuel Sossalla, Gerd Hasenfuß, Andreas Schuster, Sören J. Backhaus   +11 more
wiley   +1 more source

Updated Clinical Classification of Pulmonary Hypertension [PDF]

, 2013
In 1998, a clinical classification of pulmonary hypertension (PH) was established, categorizing PH into groups which share similar pathological and hemodynamic characteristics and therapeutic approaches.
Simonneau, Gerald, Gatzoulis, Michael A., Adatia, Ian, Celermajer, David, Denton, Chris, Ghofrani, Ardeschir, Gomez Sanchez, Miguel Angel, Krishna Kumar, R., Landzberg, Michael, Machado, Roberto F., Olschewski, Horst, Robbins, Ivan M., Souza, Rogiero   +12 more
core   +4 more sources