Results 31 to 40 of about 1,537 (148)

Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis

Clinical Pharmacology &Therapeutics, EarlyView.
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic, Deanne Nixie R. Miao, Britt I. Drögemöller, Alain Dabdoub, Julia M. Abitbol   +4 more
wiley   +1 more source

Driving after vagus nerve stimulation therapy: Is it possible?

Epilepsia Open, EarlyView.
Abstract Driving is consistently reported as an important goal for people with epilepsy. We sought to determine the proportion of people with drug‐resistant epilepsy (DRE) who became medically fit to drive after treatment with vagus nerve stimulation (VNS).
Javier Peña‐Ceballos, Tenzin Choekyi, Niamh Colleran, Breege Staunton‐Grufferty, Nicola Dempsey, David Lewis‐Smith, Hany El Naggar, Kieron J. Sweeney, Donncha O'Brien, Patrick B. Moloney, Norman Delanty   +10 more
wiley   +1 more source

Integrating Traditional Medicine to Improve the Care of Persistent Physical Symptom

Health Care Science, EarlyView.
ABSTRACT Persistent physical symptom (PPS) is a common condition in sub‐healthy population and patients with chronic disease, and significantly influences the quality of life. Many PPS cannot be explained by any known disease, and thereby are attributed to socio‐psychological reasons and treated by psychological interventions, such as cognitive ...
Huai‐Yu Wang, Ji Wang, Qi Wang
wiley   +1 more source

Increased Resting-State Cerebellar-Cerebral Functional Connectivity Underlying Chronic Tinnitus

Frontiers in Aging Neuroscience, 2018
Purpose: Chronic subjective tinnitus may arise from aberrant functional coupling between the cerebellum and the cerebral cortex. To explore this hypothesis, we used resting-state functional magnetic resonance imaging (fMRI) to illuminate the functional ...
Yuan Feng, Yu-Chen Chen, Han Lv, Wenqing Xia, Cun-Nan Mao, Fan Bo, Huiyou Chen, Jin-Jing Xu, Xindao Yin   +8 more
doaj   +1 more source

Safe Sound: Highlighting Electronic Dance Music Attendees' Unique Hearing Protection Practices

The Laryngoscope, EarlyView.
Electronic dance music attendees (EDMAs) stand out as a group more likely to use hearing protection (HP) compared to non‐EDM attendees (non‐EDMAs), making them an interesting focus for understanding the adoption of healthier auditory habits. This study delved into the factors driving HP use among EDMAs, uncovering key influences such as personal ...
Oluwatobiloba Ayo‐Ajibola, Tyler Jung, Matthew E. Lin, Ryan Long, John Parsons, Janet S. Choi, Joni Doherty   +6 more
wiley   +1 more source

Aberrant spontaneous brain activity in chronic tinnitus patients revealed by resting-state functional MRI

NeuroImage: Clinical, 2014
Objective: The neural mechanisms that give rise to the phantom sound of tinnitus are poorly understood. This study aims to investigate whether aberrant spontaneous brain activity exists in chronic tinnitus patients using resting-state functional magnetic
Yu-Chen Chen, Jian Zhang, Xiao-Wei Li, Wenqing Xia, Xu Feng, Bo Gao, Sheng-Hong Ju, Jian Wang, Richard Salvi, Gao-Jun Teng   +9 more
doaj   +1 more source

Contemporary Clinical Management of Otosyphilis for Practicing Otolaryngologists—A Scoping Review

The Laryngoscope, EarlyView.
Otosyphilis has reemerged alongside increasing syphilis rates, highlighting the need for early recognition to prevent severe audiovestibular complications. A scoping review and retrospective case series indicate that most patients present with hearing loss, tinnitus, or vertigo and typically respond to penicillin‐based treatment.
Corinne A. Pittman, Hudson Liu, Sandeep Kowkuntla, Erica Choe, Matthew J. Copeland, Michael Hoa, Selena Briggs, H. Jeffrey Kim   +7 more
wiley   +1 more source

Surgical Management of a Cerebellopontine Angle Tumor After Sudden Onset Facial Paralysis

The Laryngoscope, EarlyView.
Patients with cerebellopontine angle tumors rarely experience acute facial weakness. In this report, we summarize a case where immediate tumor decompression after a patient presented with sudden ipsilateral flaccid facial palsy resulted in complete recovery of facial nerve function, followed by staged gross total tumor resection. Return of facial nerve
Leo L. T. Meller, Douglas M. Bennion, Pradeep Kannampalli, Marc S. Schwartz, Rick A. Friedman   +4 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

Med Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin, Keyin Zheng, Aimin Jiang, Xufeng Huang, Qi Wang, András Hajdu, Zhengrui Li, Jian Zhang, Peng Luo   +8 more
wiley   +1 more source

Cognitive mechanisms in chronic tinnitus: Psychological markers of a failure to switch attention

Frontiers in Psychology, 2016
The cognitive mechanisms underpinning chronic tinnitus (phantom auditory perceptions) are underexplored but may reflect a failure to switch attention away from a tinnitus sound.
Krysta Jannaya Trevis, Neil M McLachlan, Sarah J Wilson   +2 more
doaj   +1 more source