Results 71 to 80 of about 21,955 (239)

Validation of Screening Questions for Hyperacusis in Chronic Tinnitus [PDF]

BioMed Research International, 2015
Background.We investigated the validity of the two hyperacusis items of the TSCHQ (Tinnitus Sample Case History Questionnaire) from the TRI (Tinnitus Research Initiative) database by comparing them with the German hyperacusis questionnaire GÜF.Methods.We investigated the association of the GÜF with the TSCHQ screening questions for both the sum score ...
Schecklmann, Martin, Lehner, Astrid, Schlee, Winfried, Vielsmeier, Veronika, Landgrebe, Michael, Langguth, Berthold   +5 more
openaire   +3 more sources

Tobramycin pharmacokinetic and pharmacodynamic targets in people with cystic fibrosis

British Journal of Clinical Pharmacology, EarlyView.
Intravenous tobramycin is a first‐line treatment for Pseudomonas aeruginosa infection in people with cystic fibrosis (CF). Tobramycin exhibits concentration‐dependent activity; however, excess drug exposure can lead to nephrotoxicity and ototoxicity. While dosing typically targets serum peak (Cmax) and trough (Cmin) concentrations, the area under the ...
Kiera H. Harwood, Sarah Bannister, Stephen Duffull, April Martinez, Sarath Ranganathan, Shivanthan Shanthikumar, Amanda Gwee   +6 more
wiley   +1 more source

Revisiting Baclofen for the Treatment of Severe Chronic Tinnitus [PDF]

Frontiers in Neurology, 2012
Subjective tinnitus is a phantom sensation of sound, which has been estimated to occur in 25.3% of people in the USA, with 7.9% experiencing it frequently (Shargorodsky et al., 2010). Drugs are one of a number of potential treatment avenues for severe chronic tinnitus.
Smith, Paul F., Zheng, Yiwen, Darlington, Cynthia L.   +2 more
openaire   +3 more sources

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Korean survey data reveals an association of chronic laryngitis with tinnitus in men.

PLoS ONE, 2018
The association between chronic laryngitis and tinnitus is not a well-studied topic, unlike the association of these two conditions with many other disorders.
Myung Jin Ban, Won Shik Kim, Ki Nam Park, Jae Wook Kim, Seung Won Lee, Kyungdo Han, Jae Won Chang, Hyung Kwon Byeon, Yoon Woo Koh, Jae Hong Park   +9 more
doaj   +1 more source

Cognitive mechanisms in chronic tinnitus: Psychological markers of a failure to switch attention

Frontiers in Psychology, 2016
The cognitive mechanisms underpinning chronic tinnitus (phantom auditory perceptions) are underexplored but may reflect a failure to switch attention away from a tinnitus sound.
Krysta Jannaya Trevis, Neil M McLachlan, Sarah J Wilson   +2 more
doaj   +1 more source

Clinic, Diagnosis and Treatment of Chronic Tinnitus

, 2014
Introduction. Noise in the ears (NE, tinnitus) means pathological hearing impairments or sound phenomena that occur in the ear or in the head and is one of the most common symptoms of a variety of pathological conditions.
Kitsera Al.
core   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue, Yang Zhao, Huiying Sun, Hanlin Chen, Yong Zhao, Xin Ding, Wanru Zheng, Fei Ren, Yiwei Zhao, Jiajing Tong, Yu Chen, Zhiqiang Gao, Xu Tian, Siyi Cai, Guodong Feng   +14 more
wiley   +1 more source

Chronic Tinnitus is Associated with Aging but not Dementia

Hearing Research
Abstract Background Aging is related to deterioration of bodily and neural functions, leading to various disorders and symptoms, including the development of dementia, hearing loss, or tinnitus. Understanding how these phenomena are intertwined and how aging affects those is crucial for prevention ...
Lisa Reisinger, Nathan Weisz
openaire   +2 more sources

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

JEADV Clinical Practice, EarlyView.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro, Flaminia Antonelli, Dalma Malvaso, Federica Pellegrini, Elena Ippoliti, Niccolò Gori, Ketty Peris   +6 more
wiley   +1 more source