Results 141 to 150 of about 420,376 (263)

<i>In vivo</i> safety prediction of recombinant collagen using <i>in vitro</i> simulated degradation analysis, chronic toxicity and immunological evaluation. [PDF]

Regen Biomater
Huang C, Li J, Aou X, He H, Chu Y, Gao J, Le H, Wang X, Sun H, Wang H, Zhu Z, Fan Y, Zhang G, Fan X, Yuan T.   +14 more
europepmc   +1 more source

Chemical Composition and Chronic Toxicity of Disc-Cultured Antrodia cinnamomea Fruiting Bodies. [PDF]

Toxics, 2022
Liu SC, Wu TY, Hsu TH, Lai MN, Wu YC, Ng LT.   +5 more
europepmc   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

Edible Safety Evaluation of <i>Cinnamomum camphora</i> Seed Kernel Oil: Sub-Chronic Toxicity and Teratogenicity Assessments. [PDF]

Foods
Yan X, Peng T, Zeng Z, Wang P, Gao Y, Wen X, Xia J, Gong D, Yu P.   +8 more
europepmc   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Assessment of sub-chronic toxicity and anti-aging effects of a solid self-microemulsifying drug delivery system of <i>Kaempferia parviflora</i> extract in a D-galactose-induced rat model. [PDF]

Pharm Biol
Somintara S, Sakaew W, Tuntiyasawasdikul S, Tabboon P, Mekjaruskul C, Phanphak J, Pariwatthanakun C, Sripanidkulchai B, Rudtanatip T.   +8 more
europepmc   +1 more source

Assessment of Chronic Toxicity of an Ayurvedic Herbo-Metallic Formulation Rasaraj Rasa in Wistar Rats. [PDF]

J Pharmacopuncture, 2022
Waghmare CS, Bidve SR, Gudi RV, Nalawade ML, Chawda MB.   +4 more
europepmc   +1 more source

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Evaluation of Acute and Sub-Chronic Toxicity of Lactobacillus rhamnosus GG in Sprague-Dawley Rats. [PDF]

Adv Biomed Res
Vaishnavi VVK, Banik U, Sabesan GS, Adhikary AK, Parasuraman S.   +4 more
europepmc   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source