Results 61 to 70 of about 76,687 (267)

Potential blood biomarkers for chronic traumatic encephalopathy: The multi-omics landscape of an observational cohort

Frontiers in Aging Neuroscience, 2022
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with exposure to repetitive head impacts, which is susceptible in elderly people with declined mobility, athletes of full contact sports, military personnel and victims of ...
Xintong Ge, Xintong Ge, Xintong Ge, Mengtian Guo, Mengtian Guo, Meimei Li, Meimei Li, Shishuang Zhang, Shishuang Zhang, Junlian Qiang, Luoyun Zhu, Lu Cheng, Lu Cheng, Wenzhu Li, Wenzhu Li, Yan Wang, Yan Wang, Jinwen Yu, Jinwen Yu, Zhenyu Yin, Zhenyu Yin, Fanglian Chen, Wen Tong, Ping Lei, Ping Lei, Ping Lei   +25 more
doaj   +1 more source

Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]

, 2009
Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card, Cotran, Detwiler, Foster, Foster, Fraser, Goldmann, González, González, Hamir, Hamir, Hamir, Houston, Houston, Houston, Hunter, Jeffrey, McLennan, Nakaoke, Outram, Weller, Zakharov   +21 more
core   +1 more source

Frequency and Predictors of Traumatic Encephalopathy Syndrome in a Prospective Cohort of Retired Professional Athletes

Frontiers in Neurology, 2021
Traumatic encephalopathy syndrome (TES) is proposed to represent the long-term impact of repetitive head-injury exposure and the clinical manifestation of chronic traumatic encephalopathy (CTE).
Jeff Schaffert, Nyaz Didehbani, Nyaz Didehbani, Christian LoBue, Christian LoBue, John Hart, John Hart, John Hart, Heidi Rossetti, Laura Lacritz, Laura Lacritz, C. Munro Cullum, C. Munro Cullum, C. Munro Cullum   +13 more
doaj   +1 more source

Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy

bioRxiv, 2021
Abundant filamentous inclusions of tau are characteristic of more than 20 neurodegenerative diseases that are collectively termed tauopathies. Electron cryo-microscopy (cryo-EM) structures of tau amyloid filaments from human brain revealed that distinct ...
Sofia Lövestam, F. Koh, Bart van Knippenberg, A. Kotecha, A. Murzin, M. Goedert, S. Scheres   +6 more
semanticscholar   +1 more source

Advances in Understanding Chronic Traumatic Encephalopathy: A Systematic Review of Clinical and Pathological Evidence

Forensic Sciences
Background/Objectives: Traumatic brain injury is one of the leading causes of death and disability. When traumatic brain injury is repeated over time, it can lead to the development of Chronic Traumatic Encephalopathy, a chronic neurodegenerative disease
Francesco Orsini, Giovanni Pollice, Francesco Carpano, Luigi Cipolloni, Andrea Cioffi, Camilla Cecannecchia, Roberta Bibbò, Stefania De Simone   +7 more
doaj   +1 more source

Multiple acquired portosystemic shunts in a cat secondary to chronic diaphragmatic rupture [PDF]

, 2015
A cat with a chronic diaphragmatic rupture presented with neurological signs, including twitching and focal seizures. Blood ammonia level was markedly elevated and therefore neurological signs were thought to be related to hepatic encephalopathy ...
Birchard SJ, Boudrieau SJ, Cornell KK, Wilson GP   +3 more
core   +3 more sources

Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]

, 2014
BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A, Loo, Rachel R Ogorzalek, Shen, Sean, Wanner, Ina-Beate   +3 more
core   +1 more source

Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy

bioRxiv, 2023
Subacute sclerosing panencephalitis (SSPE) occurs in some individuals after measles infection, following a symptom-free period of several years. It resembles chronic traumatic encephalopathy (CTE), which happens after repetitive head impacts or exposure ...
Chao-xiu Qi, M. Hasegawa, Masaki Takao, M. Sakai, Mayasuki Sasaki, Masashi Mizutani, A. Akagi, Y. Iwasaki, Hiroaki Miyahara, Mari Yoshida, S. Scheres, M. Goedert   +11 more
semanticscholar   +1 more source

A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

Acta Neuropathologica Communications, 2020
Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau).
Michael A. Metrick, Natália do Carmo Ferreira, Eri Saijo, Allison Kraus, Kathy Newell, Gianluigi Zanusso, Michele Vendruscolo, Bernardino Ghetti, Byron Caughey   +8 more
doaj   +1 more source

Legal medicine implications of a multidisciplinary approach to managing Traumatic Encephalopathy Syndrome in Australia

Frontiers in Neurology, 2023
The medical profession has a fundamental obligation to accurately diagnose and effectively treat a range of diseases and conditions. In the case of Traumatic Encephalopathy Syndrome (TES), where there are no universally accepted clinical diagnostic ...
Peter S. Kim, Roy G. Beran, Roy G. Beran, Roy G. Beran, Roy G. Beran, Roy G. Beran   +5 more
doaj   +1 more source