Results 91 to 100 of about 49,191 (297)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

Histopathological and clinical evaluation of chronic spontaneous urticaria patients with neutrophilic and non-neutrophilic cutaneous infiltrate

Allergology International, 2018
Background: Chronic urticaria has an expressive prevalence in general population, especially in adults, and is defined by the presence of intermittent hives for six weeks or longer.
Cíntia Freitas Martins, Karina Lopes Morais, Pamela Figueroa, Natasha Favoretto Dias, Neusa Sakai Valente, Celina Wakisaba Maruta, Paulo Ricardo Criado   +6 more
doaj   +1 more source

Interleukin 1-β, Interleukin-1 Receptor Antagonist, and Interleukin 18 in Children with Acute Spontaneous Urticaria [PDF]

, 2013
Very little is known about the role of interleukin-1β (IL-1β) and interleukin-18 (IL-18) in urticaria. Material and Methods. Serum levels of IL-1β, IL-1 receptor antagonist (IL-1RA), and IL-18 were measured in 56 children with urticaria and in 41 healthy
A. Kasperska-Zając, B. Mazur, E. Machura, M. Barć-Czarnecka, M. Szczepańska   +4 more
core   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Chronic urticaria associated with malignancies: A review article

Chronic Diseases Journal, 2019
BACKGROUND: Chronic urticaria is a cutaneous disorder defined by the presence of hives and flare for over six weeks. Etiology of chronic urticaria is not clear in 80 to 90 percent of patients.
Javad Ghaffari
doaj   +1 more source

Treatment of estrogen-induced dermatitis with omalizumab [PDF]

, 2019
In 1945, Drs Bernhard Zondek and Yehuda Bromberg demonstrated intradermal treatment with estrone and estradiol benzoate induced urticarial lesions in some patients.1 Fifty years later, Shelley et al,2 who introduced the concept of progesterone dermatitis
Baker, William H., Bell, Maria C., Heskett, Jordan B., Mousdicas, Nico, Ocana, Jesus A., Turner, Matthew J.   +5 more
core   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

Impairment of Sexual Life in 3,485 Dermatological Outpatients From a Multicentre Study in 13 European Countries [PDF]

, 2016
Skin conditions may have a strong impact on patients' sexual life, and thus influence personal relationships. Sexual issues are difficult to discuss directly in clinical practice, and a mediated instrument may be useful to capture such information.
Abeni, D., Altunay, I.K., Balieva, F., Dalgard, F., Evers, A.W.M., Finlay, A.Y., Gieler, U., Halvorsen, J.A., Jemec, G.B., Kupfer, J., Lien, L., Linder, M.D., Marron, S.E., Misery, L., Romanov, D.V., Salek, S.S., Sampogna, F., Szabo, C., Szepietowski, J.C., Titeca, G., Tomas-Aragones, L.   +20 more
core   +11 more sources

Resource reallocation across successive systemic innovations: How Rolls‐Royce shaped the evolution of the turbojet, turboprop, and turbofan

Strategic Management Journal, EarlyView.
Abstract Research Summary Despite the importance of resource reallocation in shaping a variety of strategic outcomes, strategy scholars have paid only limited attention to the processes by which firms reallocate their resources across successive systemic innovations.
Gino Cattani, Mariano Mastrogiorgio, Giuseppe Carignani   +2 more
wiley   +1 more source

Chronic Urticaria in the Real-Life Clinical Practice Setting in Portugal: Baseline Results from the Non-Interventional Multicentre AWARE Study

Acta Médica Portuguesa, 2019
Introduction: There is a paucity of information regarding chronic urticaria patients’ care in a real-world setting. The objective of this study was to report and evaluate the baseline characteristics of Portuguese chronic urticaria patients refractory ...
Ana Célia Costa, Isabel Rosmaninho, Arminda Guilherme, José Ferreira, Joana Antunes, Ana Pina, Sara Prates, João Gaspar Marques, Filomena Azevedo, Ana Paula Cunha, Celeste Brito, António Massa, João Teles de Sousa, Glória Cunha Velho, Inês Raposo, Gabriela Marques Pinto, Virgínia Sousa, Ana Rodrigues Martins   +17 more
doaj   +1 more source