Results 141 to 150 of about 423,270 (353)

Automating Vascular Biology: An End‐to‐End Automated Workflow for High‐Throughput Blood Vessel‐on‐a‐Chip Production and Multi‐Site Validation

open access: yesAdvanced Healthcare Materials, EarlyView.
AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin   +14 more
wiley   +1 more source

Engineered ETS1‐Nanoconjugate Restores Immune Homeostasis through Dual Immune‐Vascular Modulation in Relapsing and Progressive Multiple Sclerosis

open access: yesAdvanced Healthcare Materials, EarlyView.
The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang   +13 more
wiley   +1 more source

Zinc‐Containing Bioactive Glass Programs Macrophage Polarization through Extracellular Traps Regulation for Enhanced Diabetic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun   +11 more
wiley   +1 more source

Przewlekła niewydolność żylna u kobiet

open access: yesMenopause Review, 2011
Chronic venous insufficiency (CVI) is one of the most common disease affecting Western societies.Risk factors for CVI include gender, advanced age, number of pregnancies, family history, obesity , history ofdeep-vein thrombosis, exogenous hormone use ...
Joanna Tkaczuk-Włach   +2 more
doaj  

LDI, A Lipid Droplet Inhibitor, Disrupts Lipid Accumulation and Modulates Hepatic Lipid Profiles in Fatty Liver

open access: yesAdvanced Materials, EarlyView.
The lipid droplet inhibitor (LDI), templated with large‐pore mesoporous silica and functionalized with PKCα C1A and lipase, targets lipid degradation in fatty liver. The LDI maintains stable association with lipid droplets, thereby suppressing their formation and expansion.
Seunghee Kim   +12 more
wiley   +1 more source

UNDERSTANDING OF CHRONIC VENOUS DISEASES AS A MULTIDISCIPLINARY PROBLEM: SHIFTING FROM A DISEASE-SPECIFIC, LINEAR VIEW TO A COMPREHENSIVE SYSTEM PERSPECTIVE

open access: yesПаёми Сино
Chronic venous diseases (CVD) are examined in this review from the perspective of the continuity of the venous system of the lower extremities and pelvis. The review emphasizes the most clinically significant manifestations of venous insufficiency in the
SH. OLIMI   +2 more
doaj   +1 more source

Delays in Arterio-Venous Fistula Formation Among Patients With Chronic Kidney Disease; A Comparative Analysis Between Patient  and Healthcare Related Factorstween Patient and Healthcare Related Factors

open access: yesPakistan Armed Forces Medical Journal
Objective: To evaluate the factors associated with delay in arterio-venous fistula formation among the patients with chronic kidney disease on hemodialysis. Study Design: Comparative cross-sectional study.
Muhammad Arslan Javaid   +6 more
doaj   +1 more source

The effect of intravenous vitamin C on the phosphorus level reduction in hemodialysis patients: A double blind randomized clinical trial [PDF]

open access: yes, 2012
Aim The majority of hemodialysis patients are hyperphosphate-mic. Hyperphosphatemia in these patients can lead to renal oste-odystrophy, vascular calcifcation, cardiovascular events, and is independently associated with mortality risk.
Aarabi, M.   +3 more
core  

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