The arterial-venous continuum: bridging atherosclerosis and chronic venous disease through endothelial dysfunction. [PDF]
Campello E +4 more
europepmc +1 more source
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
Chronic Venous Disease and In-Hospital Venous Thromboembolism in Critically Ill Patients: A Retrospective Cohort Study of the MIMIC-IV Database. [PDF]
Yıldırım AK, Ensarioğlu M.
europepmc +1 more source
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao +11 more
wiley +1 more source
Sleep quality after endovenous ablation with concomitant phlebectomy in patients with chronic venous disease: A prospective observational study in Vietnam. [PDF]
Huyen Trang HN +8 more
europepmc +1 more source
The burden of chronic venous diseases is unknown [PDF]
openaire +2 more sources
Managing Chronic Venous Disease: An Ongoing Challenge [PDF]
de Maeseneer, M.G.R. +1 more
openaire +4 more sources
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang +7 more
wiley +1 more source
Challenges Experienced by Patients With Chronic Venous Disease in Unresolved Postoperative Recovery After Iliac Vein Stenting: A Phenomenological Study. [PDF]
Zeng YY +6 more
europepmc +1 more source
Systematic Multi‐Level Analyses Decode the Arthritis‐Neurodegeneration Axis With In Vivo Validation
Arthritis and neurodegeneration are usually studied as separate disorders, but this study connects them through population evidence, genetic inference, transcriptomic mapping, and mouse models. It highlights RNF40 as a context‐dependent joint‐brain candidate, induced in inflammatory joints yet functionally linked to dopamine‐neuron vulnerability ...
Jinwen Wang +7 more
wiley +1 more source

