Results 181 to 190 of about 318,409 (361)
152 Differences in chronic venous disease and its associated risk factors amongst hispanics and non-hispanics from a diverse Population in south Florida [PDF]
Scott Stratman +3 more
openalex +1 more source
Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li +12 more
wiley +1 more source
Endovenous thermal ablation for healing venous ulcers and preventing recurrence. [PDF]
Carradice, D +4 more
core +1 more source
Sabotaged Integral HSC Heterogeneity Underlies Essential Thrombocythemia Development
Single‐cell RNA sequencing (scRNA‐seq) maps how distinct driver mutations remodel hematopoietic stem cell (HSC) programs across essential thrombocythemia (ET). Comparative analysis uncovers both shared and subtype‐specific molecular signatures, identifies a triple‐negative (TN)‐associated HSC population enriched with malignant traits, and reveals the ...
Jingyuan Tong +21 more
wiley +1 more source
Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma +11 more
wiley +1 more source
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang +18 more
wiley +1 more source
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge +21 more
wiley +1 more source
Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source

