Results 91 to 100 of about 128,522 (343)

A Mitochondria‐Targeted Nanozyme Platform for Multi‐Pathway Tumor Therapy via Ferroptosis and Cuproptosis Regulation

Advanced Science, EarlyView.
This work reports a mitochondria‐targeted nanozyme platform, MIL‐Cu1.8S‐TPP/FA, which induces potent cuproptosis via localized delivery of Cu1.8S nanodots to mitochondria. Surface‐anchoring these nanodots onto MIL‐88B metal‐organic frameworks enhances both passive and active tumor targeting.
Chenguang Liu, Lingxiao Guo, Yuying Cheng, Jingjie Gao, Hanling Pan, Jiayi Zhu, Danting Li, Liqing Jiao, Caiyun Fu   +8 more
wiley   +1 more source

Venoplasty and Venous Stenting in Patients with Chronic Venous Insufficiency in the Lower Extremities

Journal of Tehran University Heart Center, 2017
Background: Venoplasty and stenting is a minimally invasive therapy that can be used for patients with deep venous insufficiency in the lower extremities.
Majid Moeini, Mohammad Reza Zafarghandi, Morteza Shahbandari, Azadeh Sayarifard, Morteza Taghavi, Javad Salimi, Javad Salimi, Pezhman Farshidmehr, Mohammad Hasani, Mohammad Reza Tobaei   +9 more
doaj  

Acroangiodermatitis (Pseudo-Kaposi sarcoma)

Indian Dermatology Online Journal, 2014
Acroangiodermatitis or Pseudo-Kaposi sarcoma is a rare angioproliferative entity, related to chronic venous insufficiency or certain other vascular anomalies.
Satyendra Kumar Singh, Kajal Manchanda
doaj   +1 more source

The effects of short-term use of compression stockings on health related quality of life in patients with chronic venous insufficiency

Journal of Physical Therapy Science, 2016
[Purpose] This study was aimed to analyse the effects of short-term use of compression stockings (CS) on symptoms and QoL in patients with Chronic Venous Insufficiency (CVI). [Subjects and Methods] Based on the CEAP classification C2 and C3, 117 patients
Ö. Özdemir, S. Sevim, Elif Duygu, Alper Tuğral, Y. Bakar   +4 more
semanticscholar   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

The place of subfascial endoscopic perforator vein surgery (SEPS) in advanced chronic venous insufficiency treatment

Videosurgery and Other Miniinvasive Techniques, 2011
In spite of medical science development and initiation of new technologies in minimally invasive surgery, treatmentof advanced chronic venous insufficiency at the 5th and 6th degree of CEAP classification is still a great clinical challenge.In case of no
Wiesław Pesta, Waldemar Kurpiewski, Marek Kowalczyk, Rafał Szynkarczuk, Magdalena Łuba, Anna Żurada, Radosław Grabysa   +6 more
doaj  

Adhesiveness of Blood Platelets in Arteriosclerosis Obliterans, Thromboangiitis Obliterans, Acute Thrombophlebitis, Chronic Venous Insufficiency and Arteriosclerotic Heart Disease [PDF]

, 1951
Milton E. Eisen, Mary Catherine Tyson, SIDNEY MICHAEL, FRANCES BAUMANN   +3 more
openalex   +1 more source

Frequency of Peripheral Arterial Disease in Patients With Chronic Venous Insufficiency

Iranian Red Crescent Medical Journal, 2016
Background: It is estimated that about 15% (10% - 30% in most of the studies) of the total adult population has some aspects of the Chronic Venous Insufficiency (CVI). Frequency of the Peripheral Arterial Disease (PAD) in the adult population is 3% - 4%.
M. Matic, Aleksandra Matić, V. Djuran, Z. Gajinov, S. Prcic, Z. Golušin   +5 more
semanticscholar   +1 more source

Gut Metabolite Indole‐3‐Propionic Acid Regulates Macrophage Autophagy Through PPT1 Inhibiting Aging‐Related Myocardial Fibrosis

Advanced Science, EarlyView.
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu, Hongyan Wang, Haiyu Zhang, Jiahao Li, Hanqi Li, Qiuyu Chen, Dongyu Han, Jialiang Liu, Lin Lv, Jie Xiong, Keying Yuan, Xianpeng Wei, Siqi Sheng, Fukai Liu, Yuanqi Shi, Zengxiang Dong, Yue Li   +16 more
wiley   +1 more source

Chronic Venous Insufficiency and Dystrophic Subcutaneous Calcification

Acta Médica Portuguesa, 2019
N/A.
Sara Castelo Branco, Mylene Costa, Alexandre Vasconcelos   +2 more
doaj   +1 more source