Results 101 to 110 of about 62,320 (252)

Holistic Management of Chronic Venous Ulcers: Outcomes from an Integrative Acupuncture and Naturopathy Protocol

Journal of Acupuncture Research
A 65-year-old female patient with a chronic venous leg ulcer, the most severe form of chronic venous insufficiency, underwent a 39-day inpatient program combining acupuncture and naturopathy interventions.
R. Srimathi, M. Thiruchitrampalam, N. Mangaiarkarasi   +2 more
doaj   +1 more source

Novel mechanical thrombectomy device used to restore patency to chronically occluded deep venous bypasses

Journal of Vascular Surgery Cases and Innovative Techniques
Long-standing venous thrombosis can result in chronic venous occlusions, ultimately leading to chronic venous insufficiency and venous ulcerations, a condition known as post-thrombotic syndrome.
Georges Jreij, MD, Georg J. Furtmüller, MD, Eleanor Dunlap, CRNP, DNP, Khanjan Nagarsheth, MD, MBA   +3 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Non-thermal, minimally invasive methods for the treatment of chronic venous insufficiency of the lower limbs – analysis of efficacy and safety

Journal of Education, Health and Sport
Introduction Chronic venous insufficiency of the lower limbs (CVI) is a common disorder of the venous system, leading to significant clinical symptoms and reduced quality of life in patients.
Krzysztof Szada-Borzyszkowski, Klaudia Kozyra, Sylwia Kozieł-Kwit, Filip Skowierzak, Bartłomiej Lisik, Aleksandra Sado, Mariusz Wręczycki, Kacper Sawczuk, Aleksandra Simlat, Wiktoria Rogowska   +9 more
doaj   +1 more source

Multiscale Spatial Fusion Feature‐Driven Characterization of Gastric Cancer Invasive Margins: A Multicenter Cohort Study for Preoperative Accurate Differentiation Between T4a and T4b Subtypes

Advanced Science, EarlyView.
This study develops a multi‐dimensional vision Transformer‐based model, GAVR, to accurately distinguish gastric cancer T4a/b stages preoperatively. Validated across multi‐center cohorts, it achieves excellent performance and significantly improves radiologists’ diagnostic accuracy, offering a promising tool for clinical decision‐making.
Guoliang Zheng, Xiaomiao Chai, Peng Jin, Xin Xin, Yingjie Li, Chun Yang, Jia Wei, Zishuo Yan, Jingyu Zhang, Qianning Zhao, Yingchen Han, Ning Zhang, Fuze Li, Bo Qiao, Huan Wang, Huachuan Zheng, Yan Li, Xin Zhang, Yan Zhao, Wenjun Mao, Jing Zhang   +20 more
wiley   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

Advanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo, Wei Wu, Huan Peng, Dan He, Yuxi Guo, Boyue Zhao, Xiaodan Wang, Li Ma, Yuhang Qin, Yifang Zhai, Lixia Zhuo, Ying Zhang, Yijie Guo, Linlin Jing, Fangyao Chen, Erfei Zhang, Wei Wang, Xiancang Ma, Yan Li   +18 more
wiley   +1 more source

A Novel IDO1/NE Dual Inhibitor, IMM‐H018 Prevents the Primary and Secondary Sepsis and Ameliorates the Kidney Injury Through Inhibiting the Cytokine Storm and Microthrombosis, and Reversing Immunosuppression

Advanced Science, EarlyView.
IMM‐H018, a dual IDO1/NE inhibitor, demonstrates potent therapeutic efficacy in sepsis by simultaneously targeting excessive inflammation and immune dysfunction. It prevents both primary and secondary sepsis through anti‐inflammatory, immune‐restoring, and renoprotective mechanisms, reducing organ damage, improving immune homeostasis, preserving kidney
Yi Zhou, Xiaodi Zhao, Xiaochen Pan, Zhiling Ma, Huaqing Cui, Hui Wen, Peng Wang, Xiufeng Liao, Kejie Qin, Yuchen Wang, Li Sheng, Sen Zhang   +11 more
wiley   +1 more source

Impact and effectiveness of endovascular procedures in the treatment of chronic venous insufficiency: a literature review

MGM Journal of Medical Sciences
Chronic venous insufficiency (CVI) is a prevalent vascular disorder that significantly affects patients’ quality of life. Over the past few decades, endovascular procedures have gained popularity as less invasive and effective alternatives to ...
Omar Elsaka
doaj   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

NEW TRENDS IN SURGICAL MANAGEMENT OF CHRONIC VENOUS INSUFICIENCY OF LOWER LIMBS

Zdravniški Vestnik, 2002
Background. Chronic venous insufficiency is the disease of modern world. Indications for surgical treatment of varicose veins are reviewed. Elucidated are methods of extirpation of varicose veins, safenofemoral and safenopopliteal ligature.Conclusions ...
Vladimir Valentinuzzi
doaj